Boston Red Sox vs Detroit Tigers Prediction, 5/6/2026 MLB Picks, Best Bets & Odds
Game: Boston Red Sox vs Detroit Tigers
Date: Wednesday, May 6, 2026
Location: Comerica Park in Detroit, MI
TV: Detroit SportsNet
Odds/Point Spread: Boston (-122) Detroit (+102)
The Detroit Tigers (18-18) will take on the Boston Red Sox (14-21) at Comerica Park on Wednesday. The odds on this game have Boston at -122 and Detroit is priced at +102. The over/under is 8.5. The expected starting pitchers are Jake Bennett and Jack Flaherty.

The Red Sox have recorded 58 two-baggers as a unit and have hit 24 baseballs out of the stadium. Boston owns a slugging percentage of .355 and have struck out 291 times, while drawing a walk on 117 occasions. As a team, the Boston Red Sox are compiling 3.9 runs per contest, which ranks them 26th in the league. They have amassed 130 runs batted in as well as 279 base knocks on the year, while their average at the plate is sitting at .237. They have a total of 135 runs scored and hold an on-base percentage of .316.
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They have earned a strikeout to walk ratio of 2.41 and their pitching staff has earned a collective WHIP of 1.31. Red Sox pitchers have allowed 44 home runs and also 153 total runs (15th in MLB). Boston has allowed 289 base hits (8.4 per 9 innings) in addition to 142 earned runs. The Red Sox have compiled a team earned run average of 4.14 so far this season (16th in the league), and they have rung up 279 hitters. They have walked 116 batters and their FIP is 4.47 as a squad on the season.
Red Sox pitchers have entered the game with opponents on base 32 times in addition to having 31 appearances in high leverage situations. The bullpen have recorded 18 holds on the year (19th in MLB). The Red Sox relievers have accumulated a save rate of 63.6% and stepped onto the hill in 29 save situations. They have 7 saves on the year and have blown 4 of 11 chances to get a save. The bullpen pitchers have inherited 47 base runners so far this year and 31.9% of those players crossing home plate. The Red Sox have sent 108 relief pitchers to the hill this year.
The Boston Red Sox have earned a total of 925 putouts this year, in addition to 321 assists and 18 errors. Their fielding rate is at .986 which has them ranked 17th in MLB, and have a total of 27 double plays. The Red Sox have converted 70.2% of baseballs in play into outs in their 2,775 innings, which has them ranked 14th in MLB.
Bennett has taken the mound for 5 innings and has racked up 3 K's thus far in his career. Bennett (1-0 career mark) has a FIP of 1.77 and he has gone up against 20 batters during his time in the majors. His ERA is 1.80 (1 earned runs allowed) and his WHIP is 1.400. He has allowed 5 base knocks (9.0 hits per 9 innings) and has 2 walks.
Detroit has a total of 35 HRs on the campaign as well as 154 runs batted in. They have 66 two-baggers, while taking a walk 135 times as well as putting up 162 runs. The Detroit Tigers have an OBP of .328 in addition to a team batting average of .247 on the season. The Tigers hold a team slugging percentage of .400 and they tally 4.50 runs per game (12th in MLB). They have been called out on strikes on 298 occasions (12th in MLB) and have recorded 296 base hits.
The Tigers have a WHIP of 1.318 and have a FIP of 3.77 as a pitching staff on the season. They are currently ranked 16th in baseball as a staff in total hits surrendered with 285. The Detroit pitching staff have conceded 145 runs on the season while having an ERA of 3.85 (133 earned runs conceded). They currently have a K/BB ratio of 8.60 (297 strikeouts vs 125 walks). They have allowed 29 homers and they surrender 4.19 runs per 9 innings (9th in baseball).
Detroit relievers have an inherited score rate of 37.9% out of 66 inherited runners. Their bullpen pitchers have come in 28 times in high leverage situations and on 41 occasions with runners on. With 30 save situations, the Tigers have tallied 15 holds in addition to 6 blown saves. They are ranked 22nd in MLB holding a save rate of 57.1%, and they have dispatched 106 bullpen pitchers onto the diamond so far this season.
In 2,802 innings played, the Tigers are sitting with a defensive efficiency of 69.1% (23rd in the majors). The Detroit Tigers have gotten 31 double plays and have accounted for a fielding rate of .985 (23rd in MLB). The Tigers have recorded 302 assists, 19 errors and have a total of 934 putouts during this campaign.
Flaherty (63-58 career win-loss record) has earned a 3.86 ERA while surrendering 7.6 hits per nine innings. His strikeout to walk ratio is 3.09 and he has faced 4,261 hitters in his career. He has conceded 437 ER's while earning a WHIP of 1.216 and being the owner of a FIP of 3.8. So far in his career, Flaherty has surrendered 863 hits while he has earned 1,162 punch outs in 1,019 frames.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Detroit (+102)
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Additional Resources:
Detroit Tigers - Twitter
Boston Red Sox - Twitter
