Boston Red Sox vs St. Louis Cardinals Prediction, 4/10/2026 MLB Picks, Best Bets & Odds

Game: Boston Red Sox vs St. Louis Cardinals

Date: Friday, April 10, 2026

Location: Busch Stadium in St. Louis, MO

TV: Cardinals.TV

Odds/Point Spread: Boston (+150) St. Louis (-182)

The St. Louis Cardinals (7-5) welcome the Boston Red Sox (4-8) at Busch Stadium on Friday. The odds on this game have Boston at +150 while St. Louis is priced at -182. The total has been set at 8.5. The starting pitchers are Connelly Early and Dustin May.

Boston has a slugging percentage of .356 and have been called out on strikes 114 times, while drawing a walk on 44 occasions. They have compiled 43 runs batted in in addition to 89 hits over the course of the season, while their average at the plate sits at .226. The Red Sox have accumulated 20 two-baggers as a team and have hit 9 baseballs out of the stadium. They have notched a total of 44 runs while holding a team on-base percentage of .310. As a team, the Boston Red Sox are scoring 3.7 runs per game, which is 22nd in baseball.

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The Red Sox have compiled a team ERA of 4.19 on the season (20th in baseball), and their staff has rung up 102 hitters. Red Sox pitchers have given up 13 long balls and 55 total runs (18th in the league). They have walked 46 hitters and their FIP sits at 4.28 as a squad over the course of the season. Boston has surrendered 96 base hits (8.2 per 9 innings) as well as 49 earned runs. Their strikeout to walk ratio sits at 2.22 and their pitching staff holds a collective WHIP of 1.35.

The Red Sox have sent 39 relievers to the mound for the season. The bullpen pitchers have inherited 16 runners on the season with 37.5% of those runners crossing home plate. The bullpen have earned 7 holds this year (13th in MLB). Red Sox relief pitchers have gone to the mound with players on base 11 times as well as having 14 appearances in high leverage situations. They have recorded 3 saves so far this season and have blown 2 out of their 5 save chances. The Red Sox relievers have earned a save percentage of 60.0% and stepped onto the hill in 12 save situations.

The Red Sox have transformed 68.8% of balls hit into play into outs out of 948 innings, which ranks them 18th in pro baseball. The Baltimore Orioles have accumulated 316 putouts at this point in the season, as well as 110 assists and 12 errors. Their fielding rate is currently at .973 which puts them in 29th in MLB, and have accumulated 9 double plays.

Early has taken the ball for 28 innings and has tallied 39 strikeouts in his career. His ERA is 2.55 (8 earned runs allowed) and his career WHIP is 1.241. He has conceded 25 base knocks (8.0 hits per 9 innings) with 10 walks. Early (1-2 career mark) is the owner of a FIP of 2.51 while he has gone up against 119 batters in the major leagues.

The Cardinals have a team SLG% of .361 and they are earning 4.92 runs per contest (7th in MLB). They have notched 15 two-baggers, while walking 53 times and putting up 59 runs. St. Louis has 13 home runs on the season as well as 58 runs batted in. They have been called out on strikes on 99 occasions (24th in baseball) and have 90 base knocks. The St. Louis Cardinals have accumulated a team on-base percentage of .324 and a batting average of .226 for the year.

The St. Louis pitching staff have given up 62 runs for the season while having an ERA of 4.95 (60 earned runs conceded). They have surrendered 13 long balls and they yield 5.12 runs per 9 innings (24th in MLB). The Cardinals have a team WHIP of 1.523 in addition to having a FIP of 4.95 as a staff so far this season. Their K/BB ratio is 6.10 (74 strikeouts against 53 bases on balls). They come in at 28th in the league as a pitching staff in total hits given up with 113.

They are ranked 18th in baseball holding a save percentage of 66.7%, and they have dispatched 47 relievers onto the diamond this season. Their relievers have stepped onto the hill 18 times in high leverage situations and on 17 occasions with base runners. Sitting with 18 save situations, the Cardinals have 11 holds in addition to 2 blown saves. St. Louis has had bullpen pitchers enter the game in 6 save chances and they have tallied 4 saves. St. Louis bullpen pitchers have an inherited score rate of 42.3% of 26 inherited base runners.

The St. Louis Cardinals have gotten 9 double plays and have earned a fielding percentage of .987 (13th in MLB). The Cardinals have racked up 121 assists, 6 errors and have a total of 327 putouts over the course of the season. In 981 innings on the field, the Cardinals are sitting with a efficiency on defense of 69.7% (15th in the majors).

During his MLB career, May has surrendered 293 base hits while accumulating 304 strikeouts in 331 frames. He has surrendered a total of 152 earned runs while holding a WHIP of 1.235 and having a FIP of 4.1. He has a strikeout to walk ratio of 2.62 and he has gone up against 1,396 opposing batters thus far in his career. May (19-22 career mark) is the owner of a 4.13 ERA while allowing 8.0 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take St. Louis (-182)

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