Boston Red Sox vs Toronto Blue Jays Prediction, 4/29/2026 MLB Picks, Best Bets & Odds

Game: Boston Red Sox vs Toronto Blue Jays

Date: Wednesday, April 29, 2026

Location: Rogers Centre in Toronto, ON

TV: Sportsnet

Odds/Point Spread: Boston (-144) Toronto (+120)

Rogers Centre is where the Toronto Blue Jays (12-16) will attempt to defeat the Boston Red Sox (12-17) on Wednesday. The odds on this game have the Red Sox at -144 and the Blue Jays open at +120. The betting total is set at 9. The expected starting pitchers will be Brayan Bello and Eric Lauer.

As a unit, the Boston Red Sox are recording 4.2 runs per game, which puts them at 19th in baseball. They have accounted for 122 runs scored while holding a team OBP of .314. The Red Sox have accounted for 51 two-baggers as a unit and have knocked 20 balls out of the stadium. They have earned 117 runs batted in as well as 227 base knocks on the season, and their average at the plate is sitting at .234. Boston has a slugging rate of .356 and have been called out on strikes 243 times, while drawing a walk on 99 occasions.

Get all of our MLB Picks

They have a K/BB ratio of 2.48 and the pitching staff has a collective WHIP of 1.30. Red Sox pitchers have conceded 39 home runs in addition to 128 runs in total (15th in the league). Boston has allowed 237 base hits (8.4 per 9 innings) as well as 120 earned runs. The Red Sox have a team earned run average of 4.23 on the season (17th in baseball), and their staff has rung up 236 hitters. They have walked 95 opposing batters and their FIP sits at 4.52 as a team over the course of the season.

Red Sox relief pitchers have gone to the mound with runners on base 24 times in addition to having 26 appearances in high leverage situations. The relievers have a total of 14 holds on the campaign (21st in MLB). The Red Sox bullpen have earned a save percentage of 55.6% and have come into the game in 23 save situations. They have tallied 5 saves on the season and have not converted 4 of their 9 save chances. The relief pitchers have inherited 38 runners on the campaign and 31.6% of those players ended up crossing the plate. The Red Sox have dispatched 88 relief pitchers to the mound on the season.

The Red Sox have turned 70.5% of baseballs in play into outs out of 2,298 innings on the diamond, ranking them 15th in baseball. The Boston Red Sox have a tally of 766 putouts at this point in the season, as well as 268 assists and 16 errors. Their fielding percentage is at .985 which ranks 16th in pro baseball, and have earned 20 double plays.

Bello (40-39 win-loss record in his career) sits with a FIP of 4.22 and he has gone up against 2,453 opposing hitters during his time in the majors. He has allowed 581 base knocks (9.3 hits per nine innings) with 208 free passes. His ERA is 4.28 (269 ER's allowed) and his career WHIP is 1.396. Bello has taken the hill for 565 frames and has totaled 479 K's in his pro baseball career.

The Blue Jays have a team slugging % of .379 and they average 3.93 runs per contest (27th in the league). They have hit 52 doubles, while taking a walk 77 times and putting up 110 runs. Toronto has a total of 23 long balls for the season as well as 108 RBIs. They have been rung up on 198 instances (30th in the league) and have accounted for 236 hits. The Toronto Blue Jays have a team on-base percentage of .308 and a team batting average of .249 on the campaign.

The Blue Jays have a team WHIP of 1.328 in addition to having a FIP of 3.89 as a pitching staff for the year. Their K/BB ratio sits at 9.80 (273 strikeouts against 97 walks). They rank 19th in MLB as a pitching staff in total hits conceded with 234. They have given up 32 homers and they give up 4.98 runs per 9 innings (22nd in baseball). The Toronto pitching staff have conceded 138 runs so far this season and come in with a team ERA of 4.48 (124 earned runs surrendered).

They are currently ranked 26th in baseball with a save percentage of 46.2%, and they have dispatched 108 relievers to the hill this year. Their bullpen pitchers have taken the field 38 times in high leverage situations in addition to 35 occasions with base runners. With 35 save situations, the Blue Jays have earned 20 holds and 7 blown saves. Toronto has had bullpen pitchers step onto the mound in 13 save chances and they have come away with 6 saves. Toronto relief pitchers have an inherited score percentage of 28.3% out of 46 inherited base runners.

Out of their 2,247 innings on the diamond, the Blue Jays are sitting with a defensive efficiency of 67.5% (28th in MLB). The Toronto Blue Jays have turned 21 double plays and have a fielding rate of .980 (27th in professional baseball). The Blue Jays have accrued 232 assists, 20 errors and have accounted for 749 putouts this year.

So far in his career, Lauer has conceded 698 base knocks while accumulating 688 strikeouts in 723 innings pitched. He has allowed a total of 339 earned runs while earning a WHIP of 1.336 and a FIP of 4.2. He has a strikeout to walk ratio of 2.57 and he has faced 3,106 hitters so far in his pro baseball career. Lauer (46-42 career win-loss mark) is the owner of a 4.22 ERA while allowing 8.7 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Boston (-144)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here

Get MLB picks on every single game, or if you want our very best bets by the experts, sign up for your free $60 account with a guarantee.