Chicago White Sox vs Arizona Diamondbacks Prediction, 4/23/2026 MLB Picks, Best Bets & Odds

Game: Chicago White Sox vs Arizona Diamondbacks

Date: Thursday, April 23, 2026

Location: Chase Field in Phoenix, AZ

TV: DBACKS.TV

Odds/Point Spread: Chicago (+106) Arizona (-128)

The Chicago White Sox (9-14) are en route to Chase Field on Thursday where they will take on the Arizona Diamondbacks (13-10). The line on this contest has the White Sox at +106 and the Diamondbacks are priced at -128. The total is set at 9. The expected starting pitchers are Davis Martin and Michael Soroka.

Chicago has a slugging rate of .376 and have been rung up 216 times, while drawing a walk on 91 occasions. They have tallied 84 RBI's and 165 hits so far this year, while their team batting average is sitting at .218. The White Sox have recorded 28 two-baggers as a team and have knocked 28 balls out of the stadium. They are sitting with 93 runs and hold an on-base percentage of .312. As a team, the Chicago White Sox are scoring 4.0 runs/g, which is 21st in MLB.

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They have accumulated a K/BB ratio of 1.59 and the pitching staff holds a collective WHIP of 1.46. White Sox pitchers have conceded 23 home runs in addition to 118 total runs (25th in MLB). Chicago has yielded 185 hits (8.2 per 9 innings) and 109 earned runs. The White Sox have a team ERA of 4.84 for the year (26th in the league), and the staff has rung up 175 hitters. Their pitching staff has walked 110 opposing hitters and their FIP comes in at 4.65 as a squad for the year.

The White Sox relievers have accumulated a save rate of 42.9% and have entered the game in 24 save situations. They have earned 6 saves this year and have not converted 8 out of their 14 save opportunities. The relief pitchers have inherited 50 runners so far this season with 34.0% of those runners ended up crossing the plate. White Sox relief pitchers have entered the contest with opponents on base 30 times and also have had 26 appearances in high leverage situations. The White Sox have dispatched 86 relievers to the mound this year. The relief pitchers have a total of 10 holds on the year (22nd in baseball).

The Chicago Cubs have a tally of 608 putouts for the season, in addition to 199 assists and 14 errors. Their fielding rate is holding steady at .983 which has them ranked 24th in the majors, and they have turned 16 double plays. The White Sox have turned 70.4% of baseballs in play into outs in their 1,824 innings on the diamond, which ranks them 16th in baseball.

Martin has taken the mound for 281 innings and has 218 K's in his MLB career. His ERA is 4.13 (129 ER's allowed) and he has a career WHIP of 1.295. He has allowed 268 base knocks (8.6 hits per nine innings) with 96 free passes. Martin (13-22 career record) sits with a FIP of 4.07 while going up against 1,184 batters in the major leagues.

The Diamondbacks have a team SLG% of .401 and they tally 4.52 runs per contest (13th in MLB). They have put up 48 doubles, while getting a free base 58 times and earning 104 runs. Arizona has accumulated 20 HRs for the year and 99 runs batted in. They have been rung up on 180 occasions (26th in the league) and have a total of 184 base knocks. The Arizona Diamondbacks have compiled an on-base percentage of .297 as well as a batting average of .242 for the year.

The Diamondbacks have a team WHIP of 1.298 and are the owners of a FIP of 4.42 as a squad on the campaign. They sit at 22nd in the league as a pitching staff in total hits allowed with 194. The Arizona pitching staff have relinquished 113 runs over the course of the season and come in with a team ERA of 4.32 (98 earned runs yielded). Their strikeout to walk ratio sits at 7.50 (170 strikeouts against 71 bases on balls). They have conceded 28 homers and they allow 4.98 runs per 9 innings (24th in MLB).

Arizona bullpen pitchers hold an inherited score rate of 25.0% of 32 inherited base runners. Their relief pitchers have stepped onto the hill 39 times in high leverage situations in addition to 24 occasions with runners on. With 37 save situations, the Diamondbacks have earned 22 holds and also 5 blown saves. They are ranked 14th in the league with a save percentage of 64.3%, and they have sent 81 relief pitchers to the hill so far this season.

Out of their 1,839 innings on the field, the Diamondbacks have earned a defensive efficiency of 70.9% (10th in professional baseball). The Arizona Diamondbacks have turned 15 double plays and hold a fielding percentage of .987 (13th in MLB). The Diamondbacks have 202 assists, 11 errors and have a tally of 613 putouts for the season.

So far in his career, Soroka has surrendered 386 base hits while he has accumulated 407 strikeouts in 437 frames. He has allowed 185 ER's while earning a WHIP of 1.216 and having a FIP of 3.7. He has a K/BB ratio of 2.79 and he has faced 1,835 hitters in his pro baseball career. Soroka (24-26 career win-loss mark) is the owner of a 3.81 earned run average while conceding 7.9 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Chicago (+106)

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