Chicago White Sox vs Cleveland Guardians Prediction, 9/14/2026 MLB Picks, Best Bets & Odds

Game: Chicago White Sox vs Cleveland Guardians

Date: Monday, September 14, 2026

Location: Progressive Field in Cleveland, OH

TV: MLB.TV

Odds/Point Spread: Chicago (+162) Cleveland (-196)

Progressive Field is the location where the Cleveland Guardians (75-74) will try to beat the Chicago White Sox (76-72) on Monday. The odds on this game have the White Sox at +162 and the Guardians are coming in at -196. The total comes in at 9. The pitchers taking the mound will be Davis Martin and Gavin Williams.

The White Sox have accrued 233 doubles as a team and have smacked 193 baseballs out of the park. Chicago has a slugging rate of .404 and have been rung up 1,357 times, while drawing a walk on 535 occasions. As a unit, the Chicago White Sox are recording 4.7 runs per outing, which puts them at 7th in MLB. They have accounted for 662 RBI's and 1,167 base knocks on the year, while their average at the plate sits at .235. They have racked up 694 runs while holding a team OBP of .319.

Get all of our MLB Betting Picks

They have earned a strikeout to walk ratio of 2.31 and their pitching staff has a collective WHIP of 1.31. White Sox pitchers have surrendered 165 home runs in addition to 658 runs (15th in baseball). Chicago has given up 1,202 hits (8.2 per 9 innings) in addition to 609 earned runs. The White Sox are sitting with a team earned run average of 4.16 for the year (14th in baseball), and their staff has struck out 1,224 hitters. They have walked 529 opposing players and their FIP sits at 4.27 as a unit this season.

The White Sox have sent 492 relief pitchers to the hill so far this season. The relief pitchers have inherited 237 base runners this year with 30.4% of those players earned a run for their team. The relief pitchers have 55 holds so far this season (29th in the league). White Sox relief pitchers have come into the game with opponents on base 162 times and also have had 145 appearances in high leverage situations. They have tallied 38 saves on the campaign and have blown 26 of 64 save chances. The White Sox relief pitchers have compiled a save rate of 59.4% and have stepped onto the mound in 122 save situations.

The White Sox have converted 70.3% of balls in play into outs out of 11,862 innings on the field, which has them sitting at 12th in professional baseball. The Chicago White Sox have 3,954 putouts on the year, as well as 1,201 assists and 75 errors. Their fielding percentage is currently at .986 which has them sitting 15th in MLB, and they have turned 103 double plays.

Martin (19-28 win-loss record in his career) is the owner of a FIP of 4.17 while he has faced 1,662 opposing batters in the majors. He has surrendered 385 hits (8.9 hits per 9 innings) and has 132 free passes. His earned run average is 4.23 (184 ER's allowed) and his career WHIP is 1.322. Martin has taken the hill for 391 frames and has earned 314 K's in his pro baseball career.

The Cleveland Guardians are sitting with an OBP of .314 in addition to a team batting average of .236 this season. They have struck out on 1,193 occasions (22nd in the league) and have earned 1,172 hits. Cleveland has knocked in 139 home runs on the season as well as 581 RBIs. The Guardians have a slugging percentage of .371 and they are recording 4.07 runs per game (27th in the league). They have put up 227 two-baggers, while walking 526 times and scoring 606 runs.

The Cleveland pitching staff have allowed 620 runs this year while holding an ERA of 3.80 (558 earned runs given up). They have allowed 164 dingers and they surrender 4.22 runs per 9 innings (9th in baseball). The Guardians have a WHIP of 1.263 with a FIP of 3.86 as a squad so far this season. Their K/BB ratio sits at 9.60 (1,404 strikeouts against 490 free passes). They rank 12th in baseball as a pitching staff in total hits conceded with 1,180.

With 161 save situations, the Guardians have amassed 103 holds and 15 blown saves. Cleveland has had relievers enter the contest in 56 save chances and they have converted 41 saves. Cleveland bullpen pitchers have an inherited score percentage of 27.2% out of 239 inherited runners. Their relief pitchers have come in 160 times in high leverage situations and also on 151 occasions with base runners. They rank 5th in baseball holding a save rate of 73.2%, and they have dispatched 509 relievers onto the field on the campaign.

The Cleveland Guardians have turned 97 double plays and have a fielding percentage of .985 (18th in pro baseball). The Guardians have 1,152 assists, 78 errors and have notched a total of 3,968 putouts so far this season. In their 11,904 innings on the diamond, the Guardians have earned a defensive efficiency of 69.3% (21st in MLB).

Williams (31-27 record in his career) has earned a 3.62 earned run average while allowing 7.3 hits per 9 innings. His K/BB ratio is 2.74 and he has gone up against 2,062 hitters during his pro baseball career. He has surrendered a total of 199 earned runs while holding a WHIP of 1.224 and being the owner of a FIP of 3.6. Thus far in his career, Williams has allowed 400 base hits while he has earned 561 strikeouts in 494 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Cleveland (-196)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here

Get MLB picks on every single game, or if you want our very best bets by the experts, sign up for your free $60 account with a guarantee.