Chicago White Sox vs San Francisco Giants Prediction, 5/24/2026 MLB Picks, Best Bets & Odds

Game: Chicago White Sox vs San Francisco Giants

Date: Sunday, May 24, 2026

Location: Oracle Park in San Francisco, CA

TV: NBC Bay Area

Odds/Point Spread: Chicago (+110) San Francisco (-132)

The San Francisco Giants (20-30) will play the Chicago White Sox (25-24) at Oracle Park on Sunday. The odds on this game have Chicago at +110 while San Francisco is priced at -132. The over/under is 8. The pitchers taking the mound are Noah Schultz and Robbie Ray.

Chicago has a slugging rate of .405 and have struck out 456 times, while being walked on 186 occasions. They have 207 runs batted in and 378 hits so far this season, and their team batting average is sitting at .235. The White Sox have accumulated 58 doubles as a unit and have knocked 68 balls out of the stadium. They have notched a total of 218 runs scored while having a team OBP of .323. As a unit, the Chicago White Sox are putting up 4.5 runs per game, which has them at 13th in the league.

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They have a strikeout to walk ratio of 1.97 and their pitching staff has a collective WHIP of 1.36. White Sox pitchers have allowed 53 home runs and 230 runs (21st in the league). Chicago has surrendered 388 base knocks (8.0 per 9 innings) and 210 earned runs. The White Sox have compiled a team earned run average of 4.35 on the year (23rd in the league), and their staff has struck out 395 batters. Their pitching staff has walked 201 players from the other team and their FIP comes in at 4.48 as a squad over the course of the season.

The White Sox relievers have recorded a save percentage of 59.3% and have entered the game in 43 save situations. They have 16 saves on the campaign and have not converted 11 out of their 27 save opportunities. The bullpen pitchers have inherited 86 base runners on the season and 31.4% of those players crossing the plate. White Sox relief pitchers have come into the game with runners on base 57 times in addition to having 49 appearances in high leverage situations. The White Sox have dispatched 171 relief pitchers to the mound on the campaign. The relievers have earned 16 holds this season (28th in baseball).

The White Sox have converted 70.9% of balls hit into play into outs out of their 3,912 innings, which ranks them 11th in the majors. The Chicago White Sox have earned a total of 1,304 putouts this season, as well as 432 assists and 24 errors. Their fielding rate is holding steady at .986 which ranks 17th in baseball, and have accumulated 35 double plays.

Schultz has taken the ball for 34 frames and has accumulated 32 strikeouts during his pro baseball career. His earned run average is 5.00 (19 ER's allowed) and he has a WHIP of 1.316. He has conceded 24 hits (6.3 hits per nine innings) and has had 21 free passes. Schultz (2-3 record in his career) has a FIP of 4.93 while he has faced 148 batters in the majors.

The San Francisco Giants are sitting with a team OBP of .291 and a team batting average of .244 this season. They have struck out on 391 occasions (25th in MLB) and have earned a total of 417 hits. San Francisco has recorded 41 HRs this year and 167 runs batted in. The Giants have a slugging percentage of .378 and they are scoring 3.46 runs per outing (30th in the league). They have recorded 90 two-baggers, while walking 105 times and scoring 173 runs.

The Giants are sitting with a team WHIP of 1.344 with a FIP of 4.20 as a unit for the year. They are currently ranked 19th in MLB as a staff in total hits given up with 407. The San Francisco pitching staff have given up 225 runs over the course of the season while having an ERA of 4.15 (204 earned runs given up). They currently have a strikeout to walk ratio of 7.90 (390 strikeouts against 187 bases on balls). They have given up 51 home runs and they give up 4.58 runs per 9 innings (18th in the league).

San Francisco bullpen pitchers have an inherited score percentage of 29.9% out of their 77 inherited base runners. Their relievers have stepped onto the mound 33 times in high leverage situations in addition to 52 occasions with base runners. With 43 save situations, the Giants have earned 28 holds and also 6 blown saves. They rank 18th in the league with a save percentage of 60.0%, and they have dispatched 161 bullpen pitchers to the mound this year.

The San Francisco Giants have gotten 55 double plays and hold a fielding percentage of .984 (24th in pro baseball). The Giants have recorded 500 assists, 29 errors and are sitting with 1,326 putouts so far this season. In 3,978 innings on the field, the Giants hold a defensive efficiency of 69.7% (20th in professional baseball).

Ray (91-87 record in his career) holds a 3.95 ERA while surrendering 7.8 hits per 9 innings. He has a strikeout to walk ratio of 2.83 and he has faced 6,326 hitters so far in his MLB career. He has given up 657 earned runs while holding a WHIP of 1.291 and having a FIP of 3.9. During his career, Ray has allowed 1,300 base knocks while he has earned 1,784 punch outs in 1,495 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Chicago (+110)

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