Chicago White Sox vs Seattle Mariners Prediction, 5/19/2026 MLB Picks, Best Bets & Odds

Game: Chicago White Sox vs Seattle Mariners

Date: Tuesday, May 19, 2026

Location: T-Mobile Park in Seattle, WA

TV: MLB.TV

Odds/Point Spread: Chicago (+132) Seattle (-160)

The Chicago White Sox (23-22) are hitting the road to T-Mobile Park on Tuesday where they will compete against the Seattle Mariners (22-25). The odds on this game have the White Sox at +132 while the Mariners are coming in at -160. The total is set at 9. The expected starting pitchers will be Anthony Kay and Luis Castillo.

Chicago has a slugging % of .412 and have been called out on strikes 420 times, while drawing a walk on 176 occasions. They have amassed 201 RBI's and 357 hits so far this year, and their batting average is sitting at .236. The White Sox have earned 56 doubles as a team and have hit 66 baseballs out of the park. They have 211 runs scored while holding a team on-base percentage of .325. As a unit, the Chicago White Sox are putting up 4.6 runs per game, which puts them at 10th in the league.

Get all of our MLB Parlay Picks

They have a strikeout to walk ratio of 1.91 and their pitching staff has a collective WHIP of 1.38. White Sox pitchers have given up 49 home runs in addition to 218 runs in total (23rd in the league). Chicago has relinquished 372 base knocks (8.2 per 9 innings) as well as 198 earned runs. The White Sox have a team ERA of 4.35 so far this season (22nd in the league), and their staff has struck out 366 batters. Their pitching staff has walked 192 opposing players and their FIP is 4.45 as a team for the year.

The White Sox have sent 162 relievers to the hill on the campaign. The relief pitchers have inherited 81 runners this season and 32.1% of those players earned a run for their team. The relievers are sitting with 16 holds so far this season (26th in baseball). White Sox pitchers have come into the game with players on base 54 times in addition to having 47 appearances in high leverage situations. They have recorded 15 saves for the season and have blown 11 out of their 26 chances to get a save. The White Sox relievers have earned a save percentage of 57.7% and stepped onto the hill in 42 save situations.

The Chicago White Sox are sitting with 1,229 putouts this season, as well as 417 assists and 23 errors. Their fielding percentage sits at .986 which ranks 18th in pro baseball, and they have turned 34 double plays. The White Sox have turned 70.6% of balls hit into play into outs out of 3,687 innings, which ranks them 11th in professional baseball.

Kay (7-3 win-loss mark in his career) holds a FIP of 5.20 and he has gone up against 583 batters in the major leagues. He has allowed 134 base knocks (9.6 hits per nine innings) with 66 walks. His earned run average is 5.28 (74 ER's allowed) and his WHIP is 1.586. Kay has pitched in 126 innings and has accounted for 117 punch outs so far in his MLB career.

The Seattle Mariners have tallied an on-base percentage of .319 and a batting average of .228 this season. They have been called out on strikes on 433 instances (4th in the league) and have a total of 362 hits. Seattle has compiled 54 home runs so far this season as well as 193 RBIs. The Mariners hold a slugging percentage of .376 and they average 4.12 runs per game (22nd in MLB). They have recorded 62 doubles, while taking a walk 188 times as well as scoring 198 runs.

The Seattle pitching staff have surrendered 192 runs on the campaign while holding an ERA of 3.75 (178 earned runs surrendered). They have relinquished 50 home runs and they give up 4.05 runs per 9 innings (7th in the league). The Mariners are sitting with a team WHIP of 1.234 in addition to having a FIP of 3.76 as a team for the season. Their strikeout to walk ratio is 8.60 (407 strikeouts against 122 free passes). They come in at 24th in baseball as a staff in total hits relinquished with 405.

Seattle bullpen pitchers have an inherited score rate of 14.6% of 48 inherited runners. Their relief pitchers have stepped onto the mound 59 times in high leverage situations in addition to 37 occasions with runners on. Sitting with 43 save situations, the Mariners have recorded 24 holds and 7 blown saves. They are currently ranked 17th in baseball holding a save percentage of 63.2%, and they have dispatched 149 relievers to the hill on the year.

In their 3,846 innings on the field, the Mariners are sitting with a defensive efficiency of 69.0% (25th in baseball). The Seattle Mariners have turned 45 double plays and have a fielding percentage of .990 (3rd in the majors). The Mariners have accrued 404 assists, 17 errors and have accounted for 1,282 putouts for the season.

In his career, Castillo has allowed 1,261 hits while he has tallied 1,536 punch outs in 1,454 frames. Castillo (85-88 win-loss mark in his career) holds a 3.64 earned run average and has conceded 7.8 hits per 9 innings. He has allowed 588 earned runs while earning a WHIP of 1.190 and having a FIP of 3.6. He has a strikeout to walk ratio of 3.28 and he has faced 6,026 opposing hitters so far in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Chicago (+132)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here

Get MLB picks on every single game, or if you want our very best bets by the experts, sign up for your free $60 account with a guarantee.