Cincinnati Reds vs Chicago White Sox Prediction, 8/11/2026 MLB Picks, Best Bets & Odds

Game: Cincinnati Reds vs Chicago White Sox

Date: Tuesday, August 11, 2026

Location: Rate Field in Chicago, IL

TV: Chicago Sports Network

Odds/Point Spread: Cincinnati (-145) Chicago (+125)

The Chicago White Sox (60-56) will try to beat the Cincinnati Reds (56-60) at Rate Field on Tuesday. The moneyline on this game has the Reds at -145 while the White Sox are sitting at +125. The total is 8. The starting pitchers are Nick Lodolo and Sean Burke.

Cincinnati has a slugging % of .399 and have struck out 1,104 times, while taking a walk on 424 occasions. They have compiled 458 runs batted in as well as 886 hits on the season, while their average at the plate is sitting at .229. The Reds have accrued 171 two-baggers as a unit and have smacked 154 balls out of the park. They have earned 481 runs and hold an on-base percentage of .310. As a squad, the Cincinnati Reds are compiling 4.2 runs/g, which is 22nd in the league.

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The Reds have a team ERA of 4.45 on the campaign (23rd in MLB), and the staff has struck out 929 batters. Reds pitchers have surrendered 145 home runs and 549 runs in total (21st in baseball). Their pitching staff has walked 488 batters and their FIP sits at 4.69 as a team for the year. Cincinnati has allowed 958 hits (8.4 per 9 innings) as well as 510 earned runs. They have earned a strikeout to walk ratio of 1.90 and the pitching staff holds a collective WHIP of 1.40.

Reds pitchers have entered the game with runners on 127 times in addition to having 143 appearances in high leverage situations. The bullpen have recorded 66 holds over the course of the season (11th in MLB). The Reds relief pitchers have earned a save rate of 61.7% and have entered the game in 116 save situations. They have recorded 29 saves so far this season and have blown 18 of 47 chances to save the game. The bullpen pitchers have inherited 181 base runners this year with 27.6% of them crossing home plate. The Reds have sent 410 relief pitchers to the mound on the campaign.

The Cincinnati Reds have amassed 3,093 putouts over the course of the season, as well as 945 assists and 62 errors. Their fielding percentage sits at .985 which has them sitting 18th in professional baseball, and have a total of 81 double plays. The Reds have transformed 70.6% of baseballs in play into outs out of their 9,279 innings on the diamond, ranking them 11th in pro baseball.

Lodolo has taken the mound for 471 frames and has earned 506 punch outs in his MLB career. Lodolo (27-24 win-loss record in his career) holds a FIP of 4.08 while he has gone up against 2,021 opposing batters during his time in the major leagues. His ERA is 4.14 (217 ER's allowed) and he has a WHIP of 1.247. He has given up 444 base hits (8.5 hits per 9 innings) and has had 144 free passes.

Chicago has tallied 151 long balls so far this year to go along with 526 RBIs. They have 176 doubles, while walking 392 times as well as putting up 552 runs. The Chicago White Sox have tallied an OBP of .316 and a batting average of .237 this season. The White Sox hold a slugging % of .404 and they average 4.76 runs per contest (8th in the league). They have struck out on 1,057 occasions (6th in baseball) and have notched a total of 924 base knocks.

The White Sox are sitting with a team WHIP of 1.306 in addition to having a FIP of 4.21 as a pitching staff on the campaign. Their strikeout to walk ratio comes in at 8.50 (979 strikeouts against 419 walks). They sit at 11th in baseball as a staff in total hits relinquished with 932. They have yielded 127 dingers and they concede 4.50 runs per 9 innings (17th in the league). The Chicago pitching staff have relinquished 517 runs this year and come in with a team ERA of 4.13 (474 earned runs given up).

They are ranked 24th in MLB holding a save rate of 56.9%, and they have sent 391 relief pitchers to the hill so far this year. Their relief pitchers have come in 118 times in high leverage situations and on 128 occasions with base runners. Sitting with 95 save situations, the White Sox have amassed 44 holds and 22 blown saves. Chicago has had relievers enter the contest in 51 save chances and they have tallied 29 saves. Chicago relievers hold an inherited score rate of 31.9% of 185 inherited runners.

The Chicago White Sox have turned 83 double plays and have earned a fielding percentage of .984 (19th in professional baseball). The White Sox have 957 assists, 64 errors and are sitting with 3,103 putouts for the year. In their 9,309 innings on the diamond, the White Sox are sitting with a efficiency on defense of 70.2% (12th in the majors).

Thus far in his career, Burke has allowed 248 base knocks while earning 299 K's in 281 innings pitched. He has given up a total of 110 earned runs while earning a WHIP of 1.269 and a FIP of 3.5. He has a K/BB ratio of 2.74 and he has gone up against 1,197 batters so far in his MLB career. Burke (13-17 career record) has a 3.52 ERA and has surrendered 7.9 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Chicago (+125)

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