Cincinnati Reds vs Minnesota Twins Prediction, 4/17/2026 MLB Picks, Best Bets & Odds
Game: Cincinnati Reds vs Minnesota Twins
Date: Friday, April 17, 2026
Location: Target Field in Minneapolis, MN
TV: Twins.TV
Odds/Point Spread: Cincinnati (-130) Minnesota (+110)
The Minnesota Twins (11-8) will try to beat the Cincinnati Reds (11-7) at Target Field on Friday. The odds on this game have the Reds at -130 and the Twins are sitting at +110. The over/under has been set at 8. The men taking the mound are Brandon Williamson and Joe Ryan.

As a squad, the Cincinnati Reds are putting up 3.6 runs per game, which puts them at 26th in the league. They have a total of 64 runs while holding a team OBP of .304. The Reds have earned 17 two-baggers as a unit and have hit 21 balls out of the stadium. They have accumulated 56 RBI's as well as 122 base knocks so far this season, while their average at the plate sits at .207. Cincinnati owns a slugging percentage of .346 and have struck out 164 times, while taking a walk on 80 occasions.
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Their K/BB ratio is 1.73 and their pitching staff has a team WHIP of 1.36. Reds pitchers have surrendered 17 home runs and 74 runs in total (10th in baseball). Cincinnati has allowed 141 base hits (7.8 per 9 innings) in addition to 69 earned runs. The Reds have an earned run average of 3.81 so far this year (10th in baseball), and the staff has rung up 140 batters. Their pitching staff has walked 81 hitters and their FIP comes in at 4.41 as a team for the year.
The Reds have dispatched 67 relief pitchers to the hill this season. The relievers have inherited 31 base runners over the course of the season with 22.6% of those players ended up crossing the plate. The relief pitchers have 17 holds so far this season (2nd in the league). Reds bullpen pitchers have stepped onto the hill with runners on 22 times as well as having 26 appearances in high leverage situations. They have recorded 7 saves this season and have missed out on 2 of 9 save opportunities. The Reds bullpen have a save percentage of 77.8% and have stepped onto the mound in 27 save situations.
The Chicago White Sox have a tally of 489 putouts so far this season, in addition to 159 assists and 8 errors. Their fielding percentage is holding steady at .988 which has them ranked 10th in professional baseball, and have earned 18 double plays. The Reds have transformed 71.6% of baseballs in play into outs out of 1,467 innings on the field, which ranks them 8th in pro baseball.
Williamson has taken the mound for 146 innings and has tallied 120 strikeouts during his pro baseball career. His ERA is 4.49 (73 ER's allowed) and he has a WHIP of 1.272. He has allowed 133 base knocks (8.2 hits per nine innings) and has had 53 walks. Williamson (6-6 career mark) holds a FIP of 4.43 while he has gone up against 617 batters during his time in the majors.
The Twins have a team slugging % of .399 and they are recording 5.42 runs per contest (5th in the league). They have put up 23 two-baggers, while getting a free base 82 times and scoring 103 runs. Minnesota has tallied 26 long balls for the season to go along with 98 RBIs. They have been called out on strikes on 172 occasions (6th in the league) and have totaled 143 hits. The Minnesota Twins have earned a team OBP of .333 in addition to a batting average of .232 this season.
The Twins have a team WHIP of 1.407 with a FIP of 3.83 as a pitching staff this year. They come in at 28th in the league as a pitching staff in total hits relinquished with 167. The Minnesota pitching staff have yielded 86 runs for the season while holding a team ERA of 4.26 (79 earned runs allowed). Their strikeout to walk ratio is 8.30 (154 strikeouts vs 68 free passes). They have given up 13 long balls and they relinquish 4.63 runs per 9 innings (17th in the league).
With 20 save situations, the Twins have accrued 14 holds and also 1 blown save. Minnesota has called on relief pitchers to step onto the hill in 6 save opportunities and they have earned 5 saves. Minnesota relievers have an inherited score percentage of 23.1% out of their 26 inherited base runners. Their bullpen pitchers have come in 15 times in high leverage situations in addition to 18 occasions with runners on base. They rank 4th in MLB with a save percentage of 83.3%, and they have dispatched 63 bullpen pitchers to the mound for the season.
In their 1,503 innings on the diamond, the Twins have accumulated a defensive efficiency of 67.0% (28th in baseball). The Minnesota Twins have gotten 16 double plays and have accounted for a fielding rate of .985 (18th in pro baseball). The Twins have recorded 140 assists, 10 errors and are sitting with 501 putouts so far this year.
In his pro baseball career, Ryan has surrendered 549 base hits while he has accumulated 741 strikeouts in 662 innings pitched. Ryan (48-37 career win-loss mark) has earned a 3.79 ERA while conceding 7.5 hits per nine innings. He has allowed 279 ER's while holding a WHIP of 1.062 and a FIP of 3.7. He has a strikeout to walk ratio of 4.81 and he has gone up against 2,688 batters during his career.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Minnesota (+110)
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Additional Resources:
Minnesota Twins - Twitter
Cincinnati Reds - Twitter
