Cincinnati Reds vs St. Louis Cardinals Prediction, 7/24/2026 MLB Picks, Best Bets & Odds
Game: Cincinnati Reds vs St. Louis Cardinals
Date: Friday, July 24, 2026
Location: Busch Stadium in St. Louis, MO
TV: Cardinals.TV
Odds/Point Spread: Cincinnati (-196) St. Louis (+162)
The Cincinnati Reds (47-54) are traveling to Busch Stadium on Friday where they will try to beat the St. Louis Cardinals (52-49). The odds on this game have Cincinnati at -196 and St. Louis is priced at +162. The total is 9. The pitchers taking the mound are Rhett Lowder and Dustin May.

The Reds have recorded 153 doubles as a team and have hit 134 baseballs out of the park. Cincinnati has a slugging percentage of .400 and have been called out on strikes 937 times, while drawing a walk on 365 occasions. As a team, the Cincinnati Reds are scoring 4.2 runs per outing, which ranks them 23rd in the league. They have compiled 404 RBI's and 777 base knocks so far this season, and their batting average is sitting at .230. They have accounted for 423 runs while holding a team on-base percentage of .309.
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They have accrued a K/BB ratio of 1.86 and their pitching staff has a collective WHIP of 1.43. Reds pitchers have surrendered 136 home runs and 486 runs (22nd in the league). Cincinnati has allowed 848 base knocks (8.5 per 9 innings) in addition to 455 earned runs. The Reds are sitting with a team earned run average of 4.56 so far this season (24th in the league), and their staff has struck out 815 hitters. Their pitching staff has walked 437 batters and their FIP comes in at 4.88 as a unit for the season.
The Reds have dispatched 358 relief pitchers to the mound this season. The bullpen pitchers have inherited 158 base runners over the course of the season with 27.2% of them earned a run for their team. The relievers have tallied 56 holds over the course of the season (13th in the league). Reds relief pitchers have gone to the mound with runners on 113 times in addition to having 118 appearances in high leverage situations. They have earned 23 saves this season and have blown 17 of their 40 save opportunities. The Reds bullpen have a save percentage of 57.5% and have entered the game in 97 save situations.
The Cincinnati Reds have accounted for 2,694 putouts this year, as well as 823 assists and 53 errors. Their fielding percentage is holding steady at .985 which has them ranked 17th in professional baseball, and they have turned 71 double plays. The Reds have turned 70.4% of balls hit into play into outs out of their 8,082 innings, which has them sitting 12th in professional baseball.
Lowder has taken the ball for 102 innings and has 83 K's during his MLB career. His ERA is 4.40 (50 ER's allowed) and he has a WHIP of 1.536. He has allowed 108 base hits (9.5 hits per nine innings) with 49 walks. Lowder (5-9 career record) has earned a FIP of 4.34 and he has gone up against 463 opposing batters in the majors.
St. Louis has recorded 110 HRs this season to go along with 436 runs batted in. They have recorded 133 doubles, while taking a walk 325 times and racking up 448 runs. The St. Louis Cardinals have an on-base percentage of .316 and a team batting average of .240 this year. The Cardinals have a slugging percentage of .384 and they average 4.44 runs per game (17th in the league). They have struck out on 786 occasions (27th in MLB) and have earned a total of 810 hits.
The St. Louis pitching staff have surrendered 448 runs on the year while holding a team ERA of 4.12 (412 earned runs relinquished). They have surrendered 100 homers and they surrender 4.48 runs per 9 innings (12th in the league). The Cardinals are sitting with a team WHIP of 1.329 and have a FIP of 4.15 as a squad on the campaign. Their K/BB ratio is 7.60 (764 strikeouts against 338 walks). They are sitting at 22nd in the league as a staff in total hits given up with 858.
Sitting with 121 save situations, the Cardinals have tallied 69 holds in addition to 18 blown saves. St. Louis has called on relievers to step onto the mound in 49 save opportunities and they have tallied 31 saves. St. Louis relief pitchers have an inherited score percentage of 35.2% of 162 inherited runners. Their bullpen pitchers have stepped onto the hill 121 times in high leverage situations and also on 110 occasions with runners on base. They are ranked 16th in MLB holding a save percentage of 63.3%, and they have dispatched 342 relievers to the mound this year.
The St. Louis Cardinals have gotten 91 double plays and own a fielding percentage of .988 (8th in MLB). The Cardinals have recorded 943 assists, 46 errors and have earned 2,701 putouts on the season. Out of their 8,103 innings on the field, the Cardinals have accumulated a defensive efficiency of 69.7% (18th in professional baseball).
May (24-27 career record) is the owner of a 4.07 earned run average while allowing 8.0 hits per nine innings. He has a strikeout to walk ratio of 2.70 and he has faced 1,770 opposing batters in his career. He has surrendered a total of 191 ER's while holding a WHIP of 1.227 and a FIP of 4.0. Thus far in his career, May has given up 373 base hits while he has tallied 392 K's in 422 innings pitched.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take St. Louis (+162)
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Additional Resources:
St. Louis Cardinals - Twitter
Cincinnati Reds - Twitter
