Cincinnati Reds vs St. Louis Cardinals Prediction, 7/25/2026 MLB Picks, Best Bets & Odds

Game: Cincinnati Reds vs St. Louis Cardinals

Date: Saturday, July 25, 2026

Location: Busch Stadium in St. Louis, MO

TV: Cardinals.TV

Odds/Point Spread: Cincinnati (-160) St. Louis (+132)

The Cincinnati Reds (47-54) are en route to Busch Stadium on Saturday where they will attempt to beat the St. Louis Cardinals (52-50). The moneyline on this game has Cincinnati at -160 while St. Louis is sitting at +132. The total is 8. The pitchers taking the mound are Hunter Greene and Andre Pallante.

The Reds have recorded 153 doubles as a unit and have hit 134 balls out of the park. Cincinnati has a slugging rate of .400 and have been called out on strikes 937 times, while taking a walk on 365 occasions. As a squad, the Cincinnati Reds are earning 4.2 runs per game, which has them at 23rd in the league. They have accumulated 404 RBI's as well as 777 hits this season, while their team batting average is at .230. They have 423 runs while having a team on-base percentage of .309.

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The Reds are sitting with a team earned run average of 4.56 so far this year (24th in baseball), and their staff has rung up 815 batters. Reds pitchers have conceded 136 long balls and also 486 runs (22nd in the league). Their pitching staff has walked 437 opposing players and their FIP is 4.88 as a unit so far this season. Cincinnati has allowed 848 hits (8.5 per 9 innings) and also 455 earned runs. They have earned a strikeout to walk ratio of 1.86 and the pitching staff has a collective WHIP of 1.43.

The Reds have dispatched 358 relief pitchers to the hill this year. The relief pitchers have inherited 158 runners this year with 27.2% of them ended up scoring. The relievers have racked up 56 holds on the year (13th in the league). Reds relief pitchers have entered the game with runners on base 113 times as well as having 118 appearances in high leverage situations. They have accumulated 23 saves so far this season and have blown 17 of their 40 save chances. The Reds bullpen have a save percentage of 57.5% and have entered the game in 97 save situations.

The Cincinnati Reds have earned 2,694 putouts so far this season, in addition to 823 assists and 53 errors. Their fielding rate sits at .985 which has them sitting 18th in the majors, and have a total of 71 double plays. The Reds have transformed 70.4% of balls hit into play into outs in their 8,082 innings, which ranks them 12th in professional baseball.

Greene has taken the ball for 511 innings and is sitting with 643 strikeouts in his MLB career. His ERA is 3.73 (212 ER's allowed) and he has a WHIP of 1.142. He has given up 400 hits (7.0 hits per 9 innings) with 184 free passes. Greene (27-30 mark in his career) has a FIP of 3.68 while facing 2,128 hitters in the major leagues.

The St. Louis Cardinals have a team on-base percentage of .317 in addition to a team batting average of .241 on the campaign. They have been called out on strikes on 788 occasions (27th in the league) and have 823 base hits. St. Louis has a total of 110 home runs for the year and 442 RBIs. The Cardinals hold a team slugging percentage of .384 and they are scoring 4.45 runs per contest (16th in the league). They have recorded 136 two-baggers, while walking 327 times and putting up 454 runs.

The St. Louis pitching staff have conceded 458 runs on the season while holding an ERA of 4.18 (422 earned runs conceded). They have surrendered 101 homers and they relinquish 4.53 runs per 9 innings (14th in MLB). The Cardinals hold a team WHIP of 1.339 and are the owners of a FIP of 4.16 as a unit on the campaign. Their K/BB ratio sits at 7.60 (770 strikeouts vs 343 bases on balls). They rank 22nd in the league as a pitching staff in total hits surrendered with 874.

St. Louis bullpen pitchers have an inherited score rate of 35.6% out of 163 inherited runners. Their relievers have come in 121 times in high leverage situations in addition to 111 occasions with runners on base. Sitting with 121 save situations, the Cardinals have accumulated 69 holds and 18 blown saves. They rank 16th in the league holding a save percentage of 63.3%, and they have sent 345 relievers to the hill so far this season.

The St. Louis Cardinals have gotten 93 double plays and have accounted for a fielding rate of .988 (8th in MLB). The Cardinals have 952 assists, 46 errors and have amassed 2,728 putouts for the year. Out of their 8,184 innings on the diamond, the Cardinals hold a defensive efficiency of 69.5% (20th in MLB).

In his MLB career, Pallante has conceded 574 base knocks while earning 396 punch outs in 565 frames. He has allowed 268 earned runs while holding a WHIP of 1.389 and having a FIP of 4.2. His K/BB ratio is 1.88 and he has gone up against 2,428 opposing hitters thus far in his career. Pallante (34-35 career record) has a 4.27 earned run average while conceding 9.1 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take St. Louis (+132)

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