Cincinnati Reds vs Toronto Blue Jays Prediction, 9/26/2026 MLB Picks, Best Bets & Odds

Game: Cincinnati Reds vs Toronto Blue Jays

Date: Saturday, September 26, 2026

Location: Rogers Centre in Toronto, ON

TV: Sportsnet

Odds/Point Spread: Cincinnati (+132) Toronto (-160)

Rogers Centre is where the Toronto Blue Jays (77-82) will take on the Cincinnati Reds (74-85) on Saturday. The line on this matchup has Cincinnati at +132 and Toronto is priced at -160. The total has been set at 8. The pitchers taking the mound will be Rhett Lowder and Trey Yesavage.

As a team, the Cincinnati Reds are recording 4.1 runs per game, which has them sitting at 26th in baseball. They have racked up 655 runs while having a team on-base percentage of .305. The Reds have accumulated 215 doubles as a squad and have knocked 211 balls out of the park. They have compiled 625 RBI's in addition to 1,206 hits on the year, and their team batting average is sitting at .228. Cincinnati has a slugging % of .395 and have been rung up 1,514 times, while drawing a walk on 549 occasions.

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They have a K/BB ratio of 1.94 and the pitching staff has a team WHIP of 1.45. Reds pitchers have conceded 212 home runs in addition to 814 runs in total (28th in the league). Cincinnati has conceded 1,381 base hits (8.8 per 9 innings) in addition to 759 earned runs. The Reds hold a team earned run average of 4.85 on the campaign (28th in baseball), and their staff has rung up 1,273 batters. Their pitching staff has walked 657 hitters and their FIP sits at 4.82 as a team on the year.

The Reds relievers have accumulated a save percentage of 65.6% and have come into the game in 156 save situations. They have accumulated 42 saves for the year and have not converted 22 of their 64 chances to save the game. The bullpen pitchers have inherited 241 runners for the year and 27.0% of those runners crossing home plate. Reds relief pitchers have gone to the mound with opponents on base 162 times and also have had 187 appearances in high leverage situations. The Reds have sent 565 relief pitchers to the mound on the year. The relievers have tallied 88 holds this year (12th in MLB).

The Cincinnati Reds have earned 4,225 putouts this season, in addition to 1,274 assists and 88 errors. Their fielding percentage is at .984 which is 20th in the majors, and have accumulated 112 double plays. The Reds have transformed 69.5% of baseballs in play into outs out of 12,675 innings on the field, ranking them 19th in MLB.

Lowder has taken the hill for 157 innings and is sitting with 123 strikeouts so far in his MLB career. Lowder (8-14 win-loss record in his career) is the owner of a FIP of 5.02 and he has faced 709 batters in the major leagues. His ERA is 5.09 (89 earned runs allowed) and he has a WHIP of 1.507. He has surrendered 169 hits (9.7 hits per 9 innings) and has had 68 free passes.

The Blue Jays have a SLG% of .382 and they are scoring 4.00 runs per game (30th in the league). They have hit 251 doubles, while walking 448 times as well as recording 636 runs. Toronto has accumulated 150 HRs on the year as well as 604 RBIs. They have been rung up on 1,129 occasions (29th in baseball) and have notched a total of 1,327 base knocks. The Toronto Blue Jays have a team OBP of .310 in addition to a team batting average of .248 on the campaign.

The Blue Jays hold a team WHIP of 1.295 and are the owners of a FIP of 4.00 as a squad on the campaign. They rank 7th in MLB as a staff in total hits given up with 1,239. The Toronto pitching staff have given up 683 runs on the season while having an ERA of 3.92 (613 earned runs relinquished). Their K/BB ratio is 8.80 (1,380 strikeouts against 586 walks). They have allowed 165 home runs and they allow 4.36 runs per 9 innings (11th in the league).

They sit at 3rd in MLB with a save percentage of 75.0%, and they have sent 595 relief pitchers to the hill this season. Their bullpen pitchers have stepped onto the mound 190 times in high leverage situations and also on 169 occasions with base runners. Sitting with 177 save situations, the Blue Jays have compiled 104 holds in addition to 17 blown saves. Toronto has had relief pitchers enter the contest in 68 save opportunities and they have earned 51 saves. Toronto relievers have an inherited score rate of 25.9% out of their 247 inherited runners.

The Toronto Blue Jays have gotten 107 double plays and own a fielding percentage of .983 (26th in MLB). The Blue Jays have accrued 1,334 assists, 97 errors and have a tally of 4,227 putouts for the season. In their 12,681 innings played, the Blue Jays hold a efficiency on defense of 70.2% (12th in professional baseball).

Yesavage (6-5 win-loss mark in his career) has a 3.63 ERA while giving up 6.2 hits per 9 innings. He has a K/BB ratio of 2.08 and he has faced 455 opposing hitters during his MLB career. He has given up 44 ER's while holding a WHIP of 1.172 and a FIP of 3.6. In his pro baseball career, Yesavage has given up 75 hits and he has 110 strikeouts in 109 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Cincinnati (+132)

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