Cleveland Guardians vs Baltimore Orioles Prediction, 9/7/2026 MLB Picks, Best Bets & Odds

Game: Cleveland Guardians vs Baltimore Orioles

Date: Monday, September 7, 2026

Location: Oriole Park at Camden Yards in Baltimore, MD

TV: MASN

Odds/Point Spread: Cleveland (+120) Baltimore (-144)

Oriole Park at Camden Yards is the location where the Baltimore Orioles (69-74) will go up against the Cleveland Guardians (72-71) on Monday. The odds on this game have the Guardians at +120 while the Orioles are priced at -144. The over/under comes in at 8. The pitchers taking the mound will be Joey Cantillo and Trevor Rogers.

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The Guardians have compiled 217 two-baggers as a squad and have knocked 133 balls out of the stadium. Cleveland owns a slugging percentage of .371 and have been called out on strikes 1,146 times, while being walked on 509 occasions. As a unit, the Cleveland Guardians are notching 4.0 runs per game, which puts them at 29th in the league. They have earned 554 runs batted in in addition to 1,123 base knocks so far this year, and their team batting average comes in at .236. They have notched a total of 577 runs and have an OBP of .314.

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Their strikeout to walk ratio sits at 2.85 and their pitching staff has earned a collective WHIP of 1.27. Guardians pitchers have surrendered 159 home runs in addition to 592 runs (8th in the league). Cleveland has conceded 1,138 base knocks (8.1 per 9 innings) and also 531 earned runs. The Guardians have compiled a team earned run average of 3.76 over the course of the season (7th in MLB), and the staff has rung up 1,338 batters. They have walked 469 opposing players and their FIP is 3.86 as a team over the course of the season.

The Guardians relievers have recorded a save rate of 74.1% and stepped onto the hill in 157 save situations. They have compiled 40 saves this year and have blown 14 of 54 chances to save the game. The bullpen pitchers have inherited 228 runners this year with 26.8% of those players crossing home plate. Guardians bullpen pitchers have gone to the mound with players on base 145 times as well as having 154 appearances in high leverage situations. The Guardians have sent 488 relievers to the mound over the course of the season. The bullpen have tallied 101 holds so far this year (2nd in the league).

The Cleveland Guardians have earned a total of 3,812 putouts on the year, in addition to 1,121 assists and 76 errors. Their fielding percentage sits at .985 which puts them in 18th in pro baseball, and they have turned 94 double plays. The Guardians have turned 69.3% of baseballs in play into outs out of their 11,436 innings on the diamond, which has them sitting at 22nd in pro baseball.

Cantillo has taken the mound for 275 innings and has accumulated 303 K's so far in his career. His ERA is 3.76 (115 ER's allowed) and his career WHIP is 1.377. He has given up 250 base hits (8.2 hits per nine innings) and has had 129 free passes. Cantillo (16-15 career win-loss mark) sits with a FIP of 3.70 and he has gone up against 1,181 opposing hitters during his time in the majors.

Baltimore has compiled 172 home runs over the course of the season as well as 617 RBIs. They have hit 208 two-baggers, while taking a walk 531 times and earning 640 runs. The Baltimore Orioles have accumulated an on-base percentage of .316 and a team batting average of .234 over the course of the season. The Orioles hold a team SLG% of .394 and they average 4.48 runs per contest (15th in MLB). They have struck out on 1,315 occasions (4th in baseball) and have tallied 1,116 hits.

The Baltimore pitching staff have surrendered 667 runs for the season while holding a team ERA of 4.16 (589 earned runs given up). They have conceded 152 homers and they concede 4.71 runs per 9 innings (22nd in baseball). The Orioles hold a team WHIP of 1.343 and are the owners of a FIP of 4.05 as a squad for the year. They have earned a strikeout to walk ratio of 8.10 (1,151 strikeouts vs 473 free passes). They are sitting at 26th in baseball as a staff in total hits allowed with 1,238.

Baltimore relief pitchers have an inherited score percentage of 27.7% of 188 inherited base runners. Their relief pitchers have come in 157 times in high leverage situations in addition to 141 occasions with base runners. Sitting with 141 save situations, the Orioles have earned 78 holds in addition to 21 blown saves. They are ranked 14th in the league with a save percentage of 65.0%, and they have dispatched 475 relief pitchers onto the field this season.

The Baltimore Orioles have gotten 107 double plays and own a fielding percentage of .983 (23rd in professional baseball). The Orioles have recorded 1,218 assists, 86 errors and have notched a total of 3,823 putouts on the season. In their 11,469 innings played, the Orioles have a efficiency on defense of 68.7% (27th in MLB).

Rogers (33-46 win-loss mark in his career) has earned a 3.93 earned run average and has conceded 8.4 hits per nine innings. He has a K/BB ratio of 2.81 and he has faced 2,824 batters so far in his pro baseball career. He has given up 290 earned runs while holding a WHIP of 1.286 and a FIP of 3.9. So far in his pro baseball career, Rogers has surrendered 622 base knocks while he has totaled 653 K's in 664 frames.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Cleveland (+120)

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