Cleveland Guardians vs Cincinnati Reds Prediction, 7/28/2026 MLB Picks, Best Bets & Odds

Game: Cleveland Guardians vs Cincinnati Reds

Date: Tuesday, July 28, 2026

Location: Great American Ball Park in Cincinnati, OH

TV: Reds.TV

Odds/Point Spread: Cleveland (-145) Cincinnati (+125)

The Cincinnati Reds (49-55) will compete against the Cleveland Guardians (54-53) at Great American Ball Park on Tuesday. The moneyline on this contest has Cleveland at -145 and Cincinnati is opening at +125. The over/under comes in at 9. The pitchers taking the mound are Gavin Williams and Brady Singer.

The Guardians have hit 162 doubles as a squad and have knocked 104 balls out of the stadium. Cleveland has a slugging percentage of .371 and have struck out 895 times, while being walked on 381 occasions. As a team, the Cleveland Guardians are notching 3.9 runs per contest, which has them sitting at 29th in the league. They have tallied 402 RBI's and 813 hits on the campaign, while their team batting average comes in at .230. They have accumulated 420 runs while holding a team OBP of .309.

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The Guardians have compiled a team earned run average of 3.75 this year (8th in the league), and the staff has rung up 975 hitters. Guardians pitchers have surrendered 119 long balls and 438 total runs (9th in baseball). Their pitching staff has walked 349 opposing hitters and their FIP comes in at 3.89 as a team so far this year. Cleveland has given up 853 base hits (8.1 per 9 innings) and 395 earned runs. They have earned a K/BB ratio of 2.79 and their pitching staff has earned a collective WHIP of 1.27.

Guardians bullpen pitchers have come into the game with opponents on base 106 times in addition to having 130 appearances in high leverage situations. The bullpen have tallied 86 holds this year (1st in MLB). The Guardians relievers have recorded a save percentage of 76.7% and have come into the game in 130 save situations. They have compiled 33 saves on the campaign and have blown 10 of their 43 save opportunities. The relief pitchers have inherited 162 base runners on the season with 25.3% of those players ended up scoring. The Guardians have sent 359 relievers to the mound on the campaign.

The Guardians have turned 69.5% of balls hit into play into outs out of 8,538 innings on the field, which ranks them 20th in professional baseball. The Cleveland Guardians have a tally of 2,846 putouts over the course of the season, in addition to 847 assists and 57 errors. Their fielding percentage is at .985 which ranks 18th in MLB, and have a total of 73 double plays.

Williams has taken the mound for 451 frames and has tallied 489 K's in his MLB career. Williams (28-25 career mark) has a FIP of 3.56 while he has faced 1,889 batters during his time in the majors. His earned run average is 3.61 (181 ER's allowed) and his WHIP is 1.239. He has conceded 370 hits (7.4 hits per nine innings) and has 189 walks.

The Reds hold a slugging percentage of .397 and they are scoring 4.15 runs per outing (25th in MLB). They have put up 154 two-baggers, while taking a walk 374 times as well as recording 432 runs. Cincinnati has knocked in 137 home runs for the season as well as 413 RBIs. They have been rung up on 973 instances (4th in MLB) and have a total of 801 hits. The Cincinnati Reds have an on-base percentage of .308 in addition to a batting average of .230 so far this season.

The Reds have a WHIP of 1.421 in addition to having a FIP of 4.83 as a staff for the year. They are currently ranked 17th in the league as a staff in total hits conceded with 867. The Cincinnati pitching staff have given up 498 runs so far this year while having a team ERA of 4.52 (465 earned runs relinquished). Their K/BB ratio is 8.20 (838 strikeouts against 447 walks). They have surrendered 137 long balls and they relinquish 4.85 runs per 9 innings (22nd in baseball).

Cincinnati relievers have an inherited score percentage of 26.8% out of 164 inherited base runners. Their relief pitchers have come in 125 times in high leverage situations and on 117 occasions with runners on base. With 101 save situations, the Reds have accumulated 58 holds in addition to 17 blown saves. They sit at 20th in baseball with a save percentage of 59.5%, and they have sent 369 relief pitchers to the mound this season.

In 8,325 innings played, the Reds have earned a efficiency on defense of 70.5% (11th in professional baseball). The Cincinnati Reds have turned 75 double plays and own a fielding percentage of .985 (19th in the majors). The Reds have recorded 847 assists, 56 errors and have accounted for 2,775 putouts so far this season.

So far in his pro baseball career, Singer has given up 956 hits while earning 896 strikeouts in 958 innings pitched. Singer (55-65 career record) holds a 4.26 earned run average while allowing 9.0 hits per 9 innings. He has allowed 454 ER's while earning a WHIP of 1.317 and being the owner of a FIP of 4.2. He has a K/BB ratio of 2.93 and he has gone up against 4,104 opposing batters in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Cincinnati (+125)

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