Cleveland Guardians vs Toronto Blue Jays Prediction, 4/25/2026 MLB Picks, Best Bets & Odds
Game: Cleveland Guardians vs Toronto Blue Jays
Date: Saturday, April 25, 2026
Location: Rogers Centre in Toronto, ON
TV: Sportsnet
Odds/Point Spread: Cleveland (+162) Toronto (-196)
The Toronto Blue Jays (10-14) welcome the Cleveland Guardians (14-12) at Rogers Centre on Saturday. The moneyline on this game has Cleveland at +162 and Toronto is sitting at -196. The over/under is set at 8.5. The pitchers taking the mound are Joey Cantillo and Kevin Gausman.

The Guardians have tallied 43 two-baggers as a squad and have knocked 26 balls out of the park. Cleveland has a slugging percentage of .374 and have struck out 203 times, while being walked on 104 occasions. As a squad, the Cleveland Guardians are putting up 4.0 runs per game, which has them at 22nd in the league. They have 100 RBI's in addition to 192 base knocks over the course of the season, and their average at the plate is sitting at .228. They have tallied 105 runs and hold an on-base percentage of .318.
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The Guardians are sitting with a team ERA of 4.00 this season (16th in baseball), and the staff has rung up 244 batters. Guardians pitchers have conceded 32 home runs and 111 runs (14th in the league). Their pitching staff has walked 94 opposing hitters and their FIP comes in at 4.21 as a team this year. Cleveland has allowed 196 base knocks (7.7 per 9 innings) in addition to 102 earned runs. Their K/BB ratio is 2.60 and the pitching staff holds a WHIP of 1.27.
The Guardians relief pitchers have accumulated a save percentage of 70.0% and have come into the game in 26 save situations. They have 7 saves on the campaign and have blown 3 of their 10 save chances. The bullpen pitchers have inherited 39 runners on the season with 38.5% of those players crossing the plate. Guardians relief pitchers have come into the game with runners on 23 times as well as having 28 appearances in high leverage situations. The Guardians have dispatched 84 relievers to the hill on the year. The relievers have a total of 16 holds so far this year (10th in the league).
The Cleveland Guardians have notched a total of 688 putouts this season, in addition to 195 assists and 11 errors. Their fielding rate is currently at .988 which is 10th in the majors, and have 22 double plays. The Guardians have converted 70.8% of balls in play into outs in their 2,064 innings on the field, which has them sitting 9th in baseball.
Cantillo has pitched in 159 innings and has 182 strikeouts in his career. His ERA is 3.62 (64 earned runs allowed) and his career WHIP is 1.276. He has allowed 134 base knocks (7.6 hits per 9 innings) with 69 walks. Cantillo (8-7 win-loss mark in his career) has a FIP of 3.57 while he has gone up against 667 batters in the majors.
The Blue Jays have a team slugging % of .379 and they average 3.96 runs per game (23rd in the league). They have put up 42 doubles, while walking 70 times as well as racking up 95 runs. Toronto has compiled 19 home runs on the campaign to go along with 93 runs batted in. They have been rung up on 165 occasions (30th in the league) and have earned 210 hits. The Toronto Blue Jays have an on-base percentage of .317 in addition to a team batting average of .256 so far this season.
The Toronto pitching staff have given up 120 runs for the season while holding a team ERA of 4.47 (106 earned runs relinquished). They have given up 27 homers and they allow 5.07 runs per 9 innings (24th in the league). The Blue Jays hold a team WHIP of 1.318 and have a FIP of 3.83 as a staff this season. They have earned a strikeout to walk ratio of 10.10 (240 strikeouts vs 83 walks). They come in at 15th in MLB as a staff in total hits given up with 198.
Sitting with 29 save situations, the Blue Jays have 16 holds in addition to 7 blown saves. Toronto has called on bullpen pitchers to step onto the hill in 11 save chances and they have converted 4 saves. Toronto relievers have an inherited score rate of 30.2% of 43 inherited runners. Their relievers have stepped onto the mound 36 times in high leverage situations and on 32 occasions with runners on. They are currently ranked 29th in baseball with a save percentage of 36.4%, and they have sent 93 bullpen pitchers to the mound on the campaign.
In their 1,923 innings played, the Blue Jays have a defensive efficiency of 67.3% (28th in pro baseball). The Toronto Blue Jays have turned 18 double plays and have earned a fielding percentage of .979 (27th in pro baseball). The Blue Jays have 195 assists, 18 errors and have notched a total of 641 putouts so far this year.
Gausman (113-114 career record) is the owner of a 3.80 earned run average and has allowed 8.6 hits per nine innings. His K/BB ratio is 3.68 and he has gone up against 8,099 hitters during his career. He has surrendered 818 ER's while holding a WHIP of 1.236 and a FIP of 3.7. During his pro baseball career, Gausman has surrendered 1,856 hits while accumulating 1,989 strikeouts in 1,939 frames.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Toronto (-196)
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Additional Resources:
Toronto Blue Jays - Twitter
Cleveland Guardians - Twitter
