Colorado Rockies vs Chicago White Sox Prediction, 9/25/2026 MLB Picks, Best Bets & Odds

Game: Colorado Rockies vs Chicago White Sox

Date: Friday, September 25, 2026

Location: Rate Field in Chicago, IL

TV: Chicago Sports Network

Odds/Point Spread: Colorado (+110) Chicago (-132)

Rate Field is the location where the Chicago White Sox (81-76) will take on the Colorado Rockies (57-100) on Friday. The odds on this game have Colorado at +110 while Chicago is at -132. The over/under is 8. The pitchers taking the mound will be Tomoyuki Sugano and Sean Burke.

The Rockies have tallied 274 doubles as a unit and have hit 171 baseballs out of the stadium. Colorado owns a slugging percentage of .415 and have been rung up 1,368 times, while being walked on 490 occasions. As a squad, the Colorado Rockies are recording 4.6 runs per outing, which has them at 7th in baseball. They have accounted for 698 RBI's in addition to 1,354 hits for the season, while their batting average is sitting at .253. They have earned 729 runs scored and have an OBP of .323.

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The Rockies have compiled a team ERA of 5.58 for the year (30th in MLB), and they have struck out 1,075 hitters. Rockies pitchers have allowed 216 home runs and 911 total runs (30th in baseball). They have walked 521 players from the other team and their FIP is 4.84 as a squad on the year. Colorado has given up 1,583 base hits (10.3 per 9 innings) and also 855 earned runs. They have a strikeout to walk ratio of 2.06 and the pitching staff sits with a WHIP of 1.53.

The Rockies have dispatched 486 relief pitchers to the hill this season. The bullpen pitchers have inherited 240 base runners for the year and 32.1% of them earned a run for their team. The relievers have racked up 60 holds on the year (29th in the league). Rockies relief pitchers have gone to the mound with opponents on base 156 times in addition to having 149 appearances in high leverage situations. They have recorded 33 saves so far this year and have missed out on 25 of their 58 chances to get a save. The Rockies relief pitchers have earned a save rate of 56.9% and have come into the game in 122 save situations.

The Rockies have turned 66.8% of balls hit into play into outs in their 12,408 innings on the diamond, which has them ranked 30th in professional baseball. The Colorado Rockies have accounted for 4,136 putouts thus far, as well as 1,312 assists and 96 errors. Their fielding percentage is holding at .983 which has them ranked 27th in the majors, and have 125 double plays.

Sugano (22-21 career mark) has a FIP of 4.93 while he has faced 1,306 opposing hitters in the major leagues. He has surrendered 334 hits (9.9 hits per nine innings) and has 72 free passes. His earned run average is 5.00 (169 ER's allowed) and his WHIP is 1.335. Sugano has taken the hill for 304 innings and has 197 punch outs so far in his pro baseball career.

The White Sox have a team slugging % of .404 and they are recording 4.76 runs per contest (6th in MLB). They have 245 doubles, while taking a walk 577 times as well as notching 747 runs. Chicago has knocked in 203 long balls for the season as well as 712 runs batted in. They have been rung up on 1,454 instances (5th in the league) and have accounted for 1,235 base hits. The Chicago White Sox are sitting with an OBP of .320 in addition to a team batting average of .235 for the season.

The White Sox have a WHIP of 1.316 and are the owners of a FIP of 4.27 as a squad this season. They have earned a K/BB ratio of 8.30 (1,292 strikeouts vs 561 walks). They rank 16th in the league as a staff in total hits allowed with 1,277. They have allowed 174 home runs and they allow 4.53 runs per 9 innings (14th in the league). The Chicago pitching staff have relinquished 702 runs this year while having an ERA of 4.15 (644 earned runs conceded).

Sitting with 133 save situations, the White Sox have accrued 60 holds in addition to 30 blown saves. Chicago has called on relievers to take the mound in 70 save opportunities and they have tallied 40 saves. Chicago relief pitchers have an inherited score rate of 30.4% out of 260 inherited base runners. Their relievers have taken the field 154 times in high leverage situations and also on 176 occasions with base runners. They are ranked 23rd in baseball with a save rate of 57.1%, and they have sent 523 relievers onto the field for the year.

In their 12,570 innings on the field, the White Sox have a efficiency on defense of 70.2% (12th in the majors). The Chicago White Sox have turned 109 double plays and have a fielding rate of .986 (16th in MLB). The White Sox have accrued 1,278 assists, 80 errors and have amassed 4,190 putouts this season.

In his MLB career, Burke has conceded 283 hits and he has 333 K's in 320 innings pitched. Burke (16-18 career win-loss mark) holds a 3.63 ERA and has given up 8.0 hits per nine innings. He has allowed 129 earned runs while earning a WHIP of 1.293 and having a FIP of 3.6. He has a K/BB ratio of 2.54 and he has faced 1,367 opposing batters in his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Colorado (+110)

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