Detroit Tigers vs Chicago Cubs Prediction, 7/22/2026 MLB Picks, Best Bets & Odds

Game: Detroit Tigers vs Chicago Cubs

Date: Wednesday, July 22, 2026

Location: Wrigley Field in Chicago, IL

TV: Marquee

Odds/Point Spread: Detroit (+110) Chicago (-130)

Wrigley Field is where the Chicago Cubs (56-44) will go up against the Detroit Tigers (47-53) on Wednesday. The odds on this game have the Tigers at +110 while the Cubs are priced at -130. The over/under comes in at 8. The pitchers taking the mound are Keider Montero and Colin Rea.

As a team, the Detroit Tigers are recording 4.3 runs per game, which is 20th in MLB. They have earned 426 runs while holding a team OBP of .313. The Tigers have accumulated 146 two-baggers as a unit and have knocked 122 balls out of the park. They have accrued 406 RBI's and 783 base knocks so far this year, while their batting average is sitting at .235. Detroit has a slugging % of .400 and have struck out 875 times, while drawing a walk on 354 occasions.

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They have earned a strikeout to walk ratio of 2.82 and the pitching staff holds a WHIP of 1.22. Tigers pitchers have relinquished 98 home runs in addition to 393 runs (7th in baseball). Detroit has conceded 775 base hits (7.9 per 9 innings) and also 352 earned runs. The Tigers are sitting with a team ERA of 3.59 for the year (6th in MLB), and they have struck out 839 batters. They have walked 298 opposing batters and their FIP is 3.80 as a squad on the season.

The Tigers have dispatched 307 relievers to the mound on the season. The relievers have inherited 167 runners over the course of the season with 26.9% of those runners crossing home plate. The bullpen have a total of 43 holds so far this season (24th in baseball). Tigers pitchers have come into the game with opponents on base 109 times as well as having 79 appearances in high leverage situations. They have recorded 19 saves so far this season and have blown 21 out of their 40 save opportunities. The Tigers relief pitchers have a save percentage of 47.5% and have come into the game in 85 save situations.

The Detroit Tigers have 2,648 putouts thus far, in addition to 868 assists and 45 errors. Their fielding rate sits at .987 which has them ranked 8th in professional baseball, and they have turned 69 double plays. The Tigers have transformed 70.9% of balls hit into play into outs out of their 7,944 innings on the diamond, which has them ranked 8th in pro baseball.

Montero has thrown 289 innings and is sitting with 219 punch outs in his career. Montero (17-14 career win-loss mark) is the owner of a FIP of 4.05 and he has gone up against 1,200 batters in the majors. His earned run average is 4.11 (132 ER's allowed) and he has a WHIP of 1.231. He has given up 272 hits (8.5 hits per nine innings) and has 84 walks.

The Cubs have a team slugging percentage of .413 and they average 5.08 runs per outing (5th in the league). They have 161 doubles, while taking a walk 436 times as well as scoring 508 runs. Chicago has accumulated 126 HRs on the campaign as well as 474 RBIs. They have been rung up on 847 occasions (13th in MLB) and have tallied 838 base hits. The Chicago Cubs hold a team on-base percentage of .337 and a batting average of .245 this season.

The Cubs have a team WHIP of 1.276 and have a FIP of 4.77 as a team for the season. They are sitting at 19th in baseball as a pitching staff in total hits allowed with 829. The Chicago pitching staff have surrendered 448 runs on the season and come in with a team ERA of 4.29 (424 earned runs given up). They currently have a K/BB ratio of 7.90 (780 strikeouts vs 307 walks). They have allowed 154 homers and they surrender 4.53 runs per 9 innings (14th in MLB).

With 79 save situations, the Cubs have accumulated 36 holds in addition to 17 blown saves. Chicago has had bullpen pitchers enter the game in 37 save chances and they have come away with 20 saves. Chicago relief pitchers have an inherited score percentage of 31.8% of 151 inherited runners. Their relief pitchers have come in 99 times in high leverage situations and on 103 occasions with runners on base. They rank 26th in baseball with a save rate of 54.1%, and they have sent 331 relief pitchers to the hill on the year.

In 8,013 innings on the field, the Cubs have earned a defensive efficiency of 71.7% (3rd in the majors). The Chicago Cubs have gotten 77 double plays and have notched a fielding percentage of .989 (4th in the majors). The Cubs have 926 assists, 40 errors and have a total of 2,671 putouts on the campaign.

Thus far in his career, Rea has given up 693 hits while accumulating 569 strikeouts in 706 innings pitched. He has surrendered 350 earned runs while holding a WHIP of 1.291 and having a FIP of 4.4. He has a K/BB ratio of 2.60 and he has gone up against 3,007 hitters thus far in his career. Rea (44-33 career mark) has earned a 4.46 ERA while giving up 8.8 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Detroit (+110)

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