Houston Astros vs Chicago White Sox Prediction, 7/26/2026 MLB Picks, Best Bets & Odds

Game: Houston Astros vs Chicago White Sox

Date: Sunday, July 26, 2026

Location: Rate Field in Chicago, IL

TV: Chicago Sports Network

Odds/Point Spread: Houston (-182) Chicago (+150)

The Houston Astros (51-54) are traveling to Rate Field on Sunday where they will compete against the Chicago White Sox (54-48). The line on this contest has the Astros at -182 while the White Sox are sitting at +150. The over/under is set at 8. The pitchers taking the mound are Ronel Blanco and Erick Fedde.

The Astros have hit 158 two-baggers as a squad and have smacked 143 balls out of the park. Houston owns a slugging percentage of .414 and have been called out on strikes 850 times, while drawing a walk on 345 occasions. As a unit, the Houston Astros are knocking in 4.6 runs per game, which ranks them 12th in baseball. They have earned 461 RBI's and 856 hits on the season, and their batting average comes in at .243. They have earned a total of 482 runs scored and have an on-base percentage of .316.

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The Astros have compiled a team earned run average of 4.71 on the campaign (26th in baseball), and the staff has rung up 923 batters. Astros pitchers have allowed 142 home runs and also 523 runs (25th in baseball). Their pitching staff has walked 457 players from the other team and their FIP comes in at 4.79 as a unit so far this year. Houston has allowed 837 base hits (8.1 per 9 innings) in addition to 487 earned runs. They have a strikeout to walk ratio of 2.02 and the pitching staff sits with a WHIP of 1.39.

The Astros relief pitchers have a save percentage of 83.3% and stepped onto the hill in 85 save situations. They have accumulated 30 saves on the year and have blown 6 of their 36 save chances. The relief pitchers have inherited 140 base runners on the year and 28.6% of them ended up scoring. Astros pitchers have stepped onto the hill with players on base 93 times in addition to having 101 appearances in high leverage situations. The Astros have sent 334 relief pitchers to the mound so far this season. The relief pitchers have earned 49 holds on the year (20th in the league).

The Houston Astros have amassed 2,791 putouts on the campaign, in addition to 753 assists and 43 errors. Their fielding percentage is holding steady at .988 which ranks 7th in MLB, and have a total of 82 double plays. The Astros have converted 70.7% of balls hit into play into outs out of 8,373 innings on the field, which has them sitting 10th in baseball.

Blanco has taken the ball for 278 innings and has earned 281 strikeouts in his career. His earned run average is 3.53 (109 earned runs allowed) and he has a career WHIP of 1.197. He has conceded 210 base hits (6.8 hits per nine innings) and has had 123 walks. Blanco (18-11 career win-loss mark) sits with a FIP of 3.47 while going up against 1,152 hitters in the major leagues.

The Chicago White Sox hold an OBP of .318 in addition to a batting average of .240 this season. They have been rung up on 914 occasions (7th in MLB) and have earned a total of 817 base hits. Chicago has recorded 131 home runs this year to go along with 468 RBIs. The White Sox have a SLG% of .408 and they are recording 4.78 runs per game (7th in the league). They have tallied 160 doubles, while taking a walk 346 times as well as putting up 488 runs.

The White Sox are sitting with a team WHIP of 1.315 in addition to having a FIP of 4.23 as a team for the season. They currently have a K/BB ratio of 8.60 (862 strikeouts against 379 bases on balls). They have a ranking of 8th in baseball as a staff in total hits relinquished with 808. They have allowed 110 long balls and they allow 4.47 runs per 9 innings (11th in MLB). The Chicago pitching staff have relinquished 448 runs so far this year while holding an ERA of 4.13 (414 earned runs yielded).

They rank 21st in MLB with a save rate of 58.3%, and they have dispatched 343 relievers to the hill on the season. Their relievers have taken the field 101 times in high leverage situations and also on 109 occasions with base runners. Sitting with 86 save situations, the White Sox have tallied 38 holds and 20 blown saves. Chicago has called on relief pitchers to step onto the mound in 48 save opportunities and they have earned 28 saves. Chicago relief pitchers have an inherited score percentage of 32.3% out of 164 inherited runners.

The Chicago White Sox have turned 73 double plays and have earned a fielding percentage of .986 (14th in the majors). The White Sox have recorded 844 assists, 51 errors and have earned 2,709 putouts for the season. In their 8,127 innings on the field, the White Sox have accumulated a defensive efficiency of 70.4% (12th in MLB).

Fedde (39-61 career win-loss record) holds a 4.86 ERA while allowing 9.3 hits per nine innings. He has a K/BB ratio of 1.90 and he has faced 3,766 opposing batters in his MLB career. He has allowed 467 ER's while earning a WHIP of 1.436 and a FIP of 4.8. In his pro baseball career, Fedde has given up 897 hits while he has accumulated 655 strikeouts in 865 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Chicago (+150)

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