Houston Astros vs Cleveland Guardians Prediction, 4/20/2026 MLB Picks, Best Bets & Odds

Game: Houston Astros vs Cleveland Guardians

Date: Monday, April 20, 2026

Location: Progressive Field in Cleveland, OH

TV: MLB.TV

Odds/Point Spread: Houston (+125) Cleveland (-150)

The Cleveland Guardians (12-10) are hosting the Houston Astros (8-14) at Progressive Field on Monday. The moneyline on this contest has the Astros at +125 and the Guardians are priced at -150. The over/under is 9. The pitchers who are expected to start are Colton Gordon and Slade Cecconi.

The Astros have accumulated 52 two-baggers as a squad and have knocked 26 baseballs out of the stadium. Houston is slugging .431 and have been called out on strikes 176 times, while being walked on 101 occasions. As a team, the Houston Astros are putting up 5.3 runs per contest, which is 5th in baseball. They have tallied 107 RBI's and 191 hits so far this season, while their team batting average comes in at .257. They have 116 runs while holding a team OBP of .352.

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The Astros have a team ERA of 6.19 this season (30th in the league), and they have struck out 209 hitters. Astros pitchers have yielded 34 home runs and 133 runs (29th in the league). Their pitching staff has walked 120 opposing batters and their FIP comes in at 5.41 as a unit so far this season. Houston has allowed 195 base knocks (9.2 per 9 innings) as well as 131 earned runs. They have a K/BB ratio of 1.74 and their pitching staff has a team WHIP of 1.66.

The Astros have sent 70 relief pitchers to the mound this year. The relievers have inherited 49 runners so far this year and 30.6% of those runners crossing the plate. The bullpen have a total of 8 holds for the season (27th in baseball). Astros bullpen pitchers have come into the game with runners on base 29 times as well as having 15 appearances in high leverage situations. They have recorded 5 saves for the year and have blown 0 of 5 chances to get a save. The Astros relief pitchers have recorded a save rate of 100.0% and stepped onto the hill in 13 save situations.

The Astros have turned 66.6% of balls hit into play into outs in their 1,713 innings on the field, which has them ranked 29th in the majors. The Detroit Tigers have 571 putouts on the year, in addition to 157 assists and 8 errors. Their fielding rate is currently at .989 which has them ranked 8th in the majors, and have 22 double plays.

Gordon (6-4 career win-loss record) has earned a FIP of 5.58 while he has gone up against 410 hitters in the major leagues. He has surrendered 115 base hits (11.2 hits per 9 innings) with 20 free passes. His ERA is 5.67 (58 ER's allowed) and he has a career WHIP of 1.466. Gordon has pitched in 92 innings and has tallied 82 punch outs so far in his pro baseball career.

Cleveland has hit 23 long balls this year to go along with 82 RBIs. They have recorded 40 doubles, while taking a walk 82 times and scoring 87 runs. The Cleveland Guardians have recorded a team on-base percentage of .311 in addition to a team batting average of .225 so far this season. The Guardians have a slugging percentage of .378 and they tally 3.95 runs per outing (21st in the league). They have been called out on strikes on 168 occasions (22nd in baseball) and have a total of 160 base hits.

The Cleveland pitching staff have relinquished 91 runs for the year while having an ERA of 3.96 (85 earned runs surrendered). They have given up 27 long balls and they surrender 4.24 runs per 9 innings (12th in MLB). The Guardians have a WHIP of 1.258 and are the owners of a FIP of 4.07 as a staff so far this year. They currently have a strikeout to walk ratio of 10.10 (217 strikeouts vs 81 free passes). They are currently ranked 13th in the league as a pitching staff in total hits allowed with 162.

With 24 save situations, the Guardians have accumulated 14 holds and also 3 blown saves. Cleveland has had relievers step onto the mound in 10 save chances and they have tallied 7 saves. Cleveland relievers hold an inherited score rate of 37.1% out of their 35 inherited runners. Their bullpen pitchers have taken the field 25 times in high leverage situations and also on 21 occasions with runners on base. They are currently ranked 10th in the league holding a save rate of 70.0%, and they have dispatched 69 relief pitchers to the hill for the year.

The Cleveland Guardians have gotten 18 double plays and have a fielding percentage of .991 (4th in MLB). The Guardians have recorded 157 assists, 7 errors and have 580 putouts on the campaign. In their 1,740 innings played, the Guardians have a defensive efficiency of 70.9% (12th in MLB).

Cecconi (9-17 record in his career) holds a 5.08 earned run average while allowing 9.2 hits per nine innings. His strikeout to walk ratio is 3.35 and he has gone up against 1,082 opposing hitters during his pro baseball career. He has allowed 144 earned runs while earning a WHIP of 1.270 and having a FIP of 5.0. So far in his MLB career, Cecconi has surrendered 261 base knocks while he has earned 211 K's in 255 frames.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Cleveland (-150)

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