Houston Astros vs Los Angeles Angels Prediction, 7/29/2026 MLB Picks, Best Bets & Odds

Game: Houston Astros vs Los Angeles Angels

Date: Wednesday, July 29, 2026

Location: Angel Stadium in Anaheim, CA

TV: FanDuel Sports Network West

Odds/Point Spread: Houston (-144) Los Angeles (+120)

The Houston Astros (53-55) are en route to Angel Stadium on Wednesday where they will take on the Los Angeles Angels (42-65). The moneyline on this game has Houston at -144 while Los Angeles is sitting at +120. The over/under comes in at 8.5. The starting pitchers will be Hayden Wesneski and Grayson Rodriguez.

Houston owns a slugging percentage of .411 and have struck out 878 times, while being walked on 356 occasions. They have accumulated 472 RBI's as well as 874 hits on the year, while their team batting average is sitting at .241. The Astros have accounted for 159 doubles as a squad and have knocked 147 baseballs out of the park. They have racked up 495 runs and hold an on-base percentage of .316. As a unit, the Houston Astros are putting up 4.6 runs per contest, which has them sitting at 12th in the league.

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They have earned a strikeout to walk ratio of 2.03 and the pitching staff sits with a WHIP of 1.39. Astros pitchers have given up 148 long balls in addition to 540 total runs (26th in MLB). Houston has conceded 860 base hits (8.1 per 9 innings) as well as 502 earned runs. The Astros have compiled a team ERA of 4.72 so far this year (26th in baseball), and the staff has struck out 948 batters. They have walked 468 opposing players and their FIP is 4.82 as a squad on the season.

Astros pitchers have stepped onto the hill with runners on 98 times and also have had 103 appearances in high leverage situations. The bullpen have racked up 50 holds this season (21st in the league). The Astros bullpen have accumulated a save rate of 84.2% and stepped onto the hill in 88 save situations. They have accumulated 32 saves on the year and have missed out on 6 of their 38 save chances. The relievers have inherited 148 runners for the year with 27.7% of them earned a run for their team. The Astros have dispatched 343 relievers to the hill for the year.

The Houston Astros have amassed 2,869 putouts so far this season, as well as 772 assists and 45 errors. Their fielding percentage is at .988 which puts them in 8th in baseball, and they have turned 83 double plays. The Astros have turned 70.8% of baseballs in play into outs in their 8,607 innings on the diamond, which has them ranked 8th in baseball.

Wesneski has taken the ball for 222 frames and is sitting with 212 strikeouts so far in his career. His earned run average is 4.01 (99 ER's allowed) and his WHIP is 1.158. He has conceded 191 base hits (7.7 hits per 9 innings) and has 66 walks. Wesneski (10-16 career win-loss record) has a FIP of 3.95 while going up against 925 batters during his time in the major leagues.

The Los Angeles Angels have earned a team on-base percentage of .316 and a team batting average of .239 for the season. They have been rung up on 1,011 occasions (2nd in the league) and have accounted for 860 base hits. Los Angeles has tallied 116 home runs on the campaign as well as 441 runs batted in. The Angels hold a team slugging % of .387 and they earn 4.28 runs per outing (19th in baseball). They have put up 161 doubles, while taking a walk 349 times and putting up 458 runs.

The Angels are sitting with a team WHIP of 1.366 and are the owners of a FIP of 4.32 as a unit on the season. Their K/BB ratio comes in at 9.00 (943 strikeouts vs 451 walks). They are currently ranked 9th in baseball as a pitching staff in total hits surrendered with 836. They have given up 115 homers and they relinquish 5.02 runs per 9 innings (24th in MLB). The Los Angeles pitching staff have conceded 525 runs for the season and come in with a team ERA of 4.55 (476 earned runs yielded).

Los Angeles bullpen pitchers hold an inherited score rate of 38.7% out of 181 inherited runners. Their bullpen pitchers have stepped onto the mound 113 times in high leverage situations in addition to 112 occasions with runners on base. Sitting with 92 save situations, the Angels have 58 holds in addition to 19 blown saves. They rank 30th in baseball with a save rate of 40.6%, and they have dispatched 345 relievers onto the field on the year.

In 8,481 innings on the diamond, the Angels hold a defensive efficiency of 70.0% (13th in MLB). The Los Angeles Angels have gotten 67 double plays and have a fielding percentage of .983 (23rd in MLB). The Angels have recorded 891 assists, 64 errors and have accounted for 2,827 putouts during this campaign.

So far in his MLB career, Rodriguez has allowed 281 hits while totaling 289 strikeouts in 277 frames. He has given up a total of 146 earned runs while earning a WHIP of 1.364 and having a FIP of 4.7. His strikeout to walk ratio is 2.98 and he has faced 1,192 opposing hitters thus far in his career. Rodriguez (23-11 career mark) has a 4.74 earned run average while allowing 9.1 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Houston (-144)

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