Houston Astros vs Sacramento Athletics Prediction, 9/26/2026 MLB Picks, Best Bets & Odds

Game: Houston Astros vs Sacramento Athletics

Date: Saturday, September 26, 2026

Location: Sutter Health Park in West Sacramento, CA

TV: NBC Sports California

Odds/Point Spread: Houston (-145) Sacramento (+125)

The Houston Astros (79-80) are en route to Sutter Health Park on Saturday where they will take on the Sacramento Athletics (63-96). The moneyline on this contest has the Astros at -145 while the Athletics are at +125. The over/under comes in at 8.5. The expected starting pitchers are Hayden Wesneski and Jack Perkins.

The Astros have hit 232 two-baggers as a unit and have knocked 218 balls out of the park. Houston is slugging .414 and have been called out on strikes 1,313 times, while drawing a walk on 512 occasions. As a team, the Houston Astros are compiling 4.5 runs per game, which ranks them 15th in MLB. They have amassed 676 RBI's and 1,287 base knocks over the course of the season, while their team batting average comes in at .241. They have accounted for 707 runs scored and have an OBP of .313.

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They have earned a K/BB ratio of 2.17 and their pitching staff has earned a collective WHIP of 1.35. Astros pitchers have conceded 204 home runs and 758 runs (24th in baseball). Houston has conceded 1,257 base hits (8.0 per 9 innings) in addition to 706 earned runs. The Astros hold a team ERA of 4.50 so far this year (24th in the league), and the staff has rung up 1,389 batters. Their pitching staff has walked 641 opposing hitters and their FIP is 4.56 as a team for the season.

Astros relief pitchers have stepped onto the hill with runners on 151 times in addition to having 165 appearances in high leverage situations. The relievers have a total of 87 holds so far this season (13th in the league). The Astros bullpen have earned a save rate of 79.0% and have come into the game in 151 save situations. They have earned 49 saves on the season and have blown 13 of 62 chances to get a save. The relievers have inherited 227 runners so far this season with 25.6% of those players crossing home plate. The Astros have sent 519 relief pitchers to the hill so far this season.

The Astros have turned 70.8% of baseballs in play into outs in their 12,699 innings, ranking them 9th in MLB. The Houston Astros have earned a total of 4,233 putouts so far this season, in addition to 1,173 assists and 70 errors. Their fielding percentage is currently at .987 which has them sitting 8th in the majors, and have 126 double plays.

Wesneski (15-18 career record) has earned a FIP of 3.85 while he has gone up against 1,144 hitters during his time in the major leagues. He has allowed 234 hits (7.6 hits per nine innings) with 85 free passes. His earned run average is 3.91 (120 earned runs allowed) and his career WHIP is 1.156. Wesneski has taken the mound for 276 frames and has earned 253 K's so far in his career.

The Sacramento Athletics have compiled a team OBP of .318 and a batting average of .246 so far this season. They have been called out on strikes on 1,351 occasions (12th in the league) and have notched a total of 1,326 base knocks. Sacramento has accounted for 194 home runs on the year as well as 662 RBIs. The Athletics hold a team slugging % of .405 and they are recording 4.35 runs per outing (20th in baseball). They have hit 244 doubles, while walking 511 times as well as scoring 691 runs.

The Sacramento pitching staff have surrendered 910 runs on the season while having an ERA of 5.44 (848 earned runs given up). They have surrendered 239 dingers and they allow 5.84 runs per 9 innings (29th in baseball). The Athletics hold a team WHIP of 1.503 and have a FIP of 4.90 as a pitching staff for the season. Their K/BB ratio sits at 8.50 (1,326 strikeouts against 619 bases on balls). They are currently ranked 29th in MLB as a pitching staff in total hits conceded with 1,490.

They sit at 22nd in the league holding a save percentage of 57.6%, and they have dispatched 544 bullpen pitchers onto the field over the course of the season. Their relief pitchers have come in 148 times in high leverage situations and on 176 occasions with runners on base. Sitting with 152 save situations, the Athletics have amassed 83 holds in addition to 28 blown saves. Sacramento has had bullpen pitchers take the mound in 66 save opportunities and they have come away with 38 saves. Sacramento relievers hold an inherited score percentage of 36.7% of 267 inherited runners.

In 12,627 innings on the diamond, the Athletics hold a efficiency on defense of 67.6% (29th in pro baseball). The Sacramento Athletics have turned 120 double plays and have a fielding percentage of .986 (13th in the majors). The Athletics have recorded 1,206 assists, 75 errors and have notched a total of 4,209 putouts on the season.

Perkins (6-14 career win-loss mark) has earned a 5.49 ERA while surrendering 8.6 hits per nine innings. He has a strikeout to walk ratio of 2.55 and he has gone up against 680 opposing hitters so far in his MLB career. He has given up a total of 94 earned runs while holding a WHIP of 1.381 and a FIP of 5.4. So far in his career, Perkins has allowed 147 hits while he has totaled 168 strikeouts in 154 frames.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Houston (-145)

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