Houston Astros vs San Diego Padres Prediction, 8/7/2026 MLB Picks, Best Bets & Odds

Game: Houston Astros vs San Diego Padres

Date: Friday, August 7, 2026

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Houston (+132) San Diego (-160)

The San Diego Padres (59-56) are welcoming the Houston Astros (59-57) at Petco Park on Friday. The moneyline on this game has the Astros at +132 and the Padres are at -160. The total comes in at 9. The expected starting pitchers will be Ronel Blanco and Robbie Ray.

The Astros have tallied 175 two-baggers as a unit and have hit 157 baseballs out of the park. Houston is slugging .416 and have struck out 950 times, while taking a walk on 393 occasions. As a unit, the Houston Astros are notching 4.7 runs per outing, which is 9th in MLB. They have tallied 514 runs batted in and 965 base knocks on the campaign, while their batting average is .246. They have tallied 540 runs while holding a team on-base percentage of .322.

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The Astros have a team earned run average of 4.60 so far this year (25th in MLB), and their staff has struck out 1,020 batters. Astros pitchers have surrendered 155 home runs and 565 total runs (25th in baseball). Their pitching staff has walked 484 opposing hitters and their FIP sits at 4.69 as a squad over the course of the season. Houston has conceded 914 hits (8.0 per 9 innings) and also 526 earned runs. Their strikeout to walk ratio is 2.11 and their pitching staff has earned a collective WHIP of 1.36.

Astros relief pitchers have stepped onto the hill with players on base 106 times as well as having 114 appearances in high leverage situations. The relievers have 54 holds so far this season (21st in the league). The Astros relievers have earned a save rate of 83.7% and stepped onto the hill in 98 save situations. They have earned 36 saves this season and have missed out on 7 of their 43 save opportunities. The relievers have inherited 157 base runners on the season with 26.8% of those runners ended up scoring. The Astros have dispatched 370 relief pitchers to the hill for the season.

The Astros have turned 71.0% of balls in play into outs out of 9,264 innings on the diamond, which has them sitting 7th in pro baseball. The Houston Astros are sitting with 3,088 putouts this season, in addition to 846 assists and 49 errors. Their fielding percentage is holding steady at .988 which has them sitting 8th in MLB, and they have turned 91 double plays.

Blanco (18-12 career win-loss mark) has earned a FIP of 3.60 and he has faced 1,195 batters in the major leagues. He has conceded 219 hits (6.8 hits per nine innings) and has 128 free passes. His earned run average is 3.65 (117 earned runs allowed) and he has a WHIP of 1.204. Blanco has taken the mound for 288 innings and has accumulated 289 punch outs so far in his pro baseball career.

The San Diego Padres have accounted for an on-base percentage of .312 in addition to a batting average of .235 on the season. They have been called out on strikes on 945 occasions (18th in baseball) and have notched a total of 891 hits. San Diego has 122 home runs on the season as well as 471 RBIs. The Padres have a SLG% of .382 and they tally 4.23 runs per contest (21st in the league). They have 171 doubles, while taking a walk 391 times as well as racking up 486 runs.

The Padres are sitting with a team WHIP of 1.330 and have a FIP of 4.23 as a squad this season. They rank 18th in baseball as a pitching staff in total hits relinquished with 949. The San Diego pitching staff have given up 503 runs so far this season and come in with a team ERA of 4.21 (474 earned runs yielded). Their strikeout to walk ratio is 8.30 (932 strikeouts vs 400 walks). They have yielded 129 long balls and they concede 4.46 runs per 9 innings (14th in baseball).

They rank 10th in the league with a save percentage of 69.4%, and they have sent 391 bullpen pitchers onto the diamond this year. Their bullpen pitchers have taken the field 132 times in high leverage situations and on 116 occasions with runners on base. Sitting with 121 save situations, the Padres have 69 holds in addition to 15 blown saves. San Diego has had relievers enter the contest in 49 save opportunities and they have walked away with 34 saves. San Diego relievers have an inherited score rate of 32.5% out of their 197 inherited runners.

The San Diego Padres have turned 94 double plays and hold a fielding percentage of .989 (4th in professional baseball). The Padres have recorded 1,011 assists, 46 errors and have a tally of 3,042 putouts for the season. In 9,126 innings on the field, the Padres have earned a defensive efficiency of 69.9% (14th in MLB).

During his pro baseball career, Ray has allowed 1,351 hits while totaling 1,841 strikeouts in 1,563 innings pitched. Ray (98-87 career win-loss record) has a 3.87 earned run average while allowing 7.8 hits per 9 innings. He has allowed 673 earned runs while holding a WHIP of 1.290 and having a FIP of 3.8. His strikeout to walk ratio is 2.77 and he has gone up against 6,609 batters during his career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Houston (+132)

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