Houston Astros vs Seattle Mariners Prediction, 4/10/2026 MLB Picks, Best Bets & Odds

Game: Houston Astros vs Seattle Mariners

Date: Friday, April 10, 2026

Location: T-Mobile Park in Seattle, WA

TV: MLB.TV

Odds/Point Spread: Houston (-122) Seattle (+102)

The Houston Astros (6-7) are hitting the road to T-Mobile Park on Friday where they will take on the Seattle Mariners (4-9). The odds on this game have Houston at -122 and Seattle is sitting at +102. The over/under is 8. The expected starting pitchers will be Tatsuya Imai and Emerson Hancock.

As a unit, the Houston Astros are compiling 6.1 runs per game, which has them sitting at 2nd in MLB. They have notched a total of 79 runs scored while holding a team OBP of .371. The Astros have tallied 34 doubles as a squad and have hit 16 baseballs out of the stadium. They have accounted for 73 runs batted in and 122 hits this season, and their team batting average comes in at .271. Houston has a slugging rate of .453 and have been called out on strikes 101 times, while being walked on 67 occasions.

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They have accumulated a K/BB ratio of 1.84 and their pitching staff has a team WHIP of 1.63. Astros pitchers have yielded 20 home runs and 78 total runs (29th in MLB). Houston has allowed 114 hits (9.1 per 9 innings) in addition to 76 earned runs. The Astros have a team ERA of 6.05 over the course of the season (29th in the league), and their staff has struck out 129 hitters. They have walked 70 opposing hitters and their FIP is 5.22 as a unit for the year.

The Astros bullpen have recorded a save percentage of 100.0% and have come into the game in 6 save situations. They have tallied 3 saves this year and have blown 0 of 3 chances to save the game. The bullpen pitchers have inherited 28 base runners on the year and 39.3% of those runners ended up crossing the plate. Astros pitchers have entered the game with runners on 17 times as well as having 7 appearances in high leverage situations. The Astros have dispatched 40 relief pitchers to the mound this season. The bullpen have 3 holds on the year (28th in baseball).

The Astros have converted 66.3% of balls hit into play into outs out of 1,017 innings, which ranks them 28th in the majors. The Detroit Tigers have accounted for 339 putouts this season, in addition to 95 assists and 4 errors. Their fielding percentage sits at .991 which ranks 7th in professional baseball, and they have turned 17 double plays.

Imai (1-0 career win-loss record) has earned a FIP of 4.38 while he has gone up against 37 batters in the majors. He has given up 6 base hits (6.7 hits per nine innings) and has had 7 walks. His ERA is 4.44 (4 ER's allowed) and he has a career WHIP of 1.605. Imai has taken the ball for 8 innings and has racked up 13 K's so far in his career.

The Mariners have a team slugging % of .301 and they score 3.08 runs per game (30th in MLB). They have recorded 13 two-baggers, while walking 49 times as well as scoring 40 runs. Seattle has compiled 11 home runs for the year as well as 39 RBIs. They have been rung up on 133 instances (2nd in the league) and have notched a total of 78 hits. The Seattle Mariners have accumulated a team on-base percentage of .280 and a batting average of .184 so far this season.

The Seattle pitching staff have allowed 42 runs for the year while holding a team ERA of 2.63 (34 earned runs allowed). They have surrendered 8 homers and they allow 3.25 runs per 9 innings (3rd in MLB). The Mariners hold a team WHIP of 0.955 in addition to having a FIP of 2.86 as a team this season. Their K/BB ratio sits at 9.20 (119 strikeouts against 26 bases on balls). They come in at 7th in baseball as a staff in total hits conceded with 85.

Sitting with 5 save situations, the Mariners have compiled 1 hold in addition to 2 blown saves. Seattle has called on relievers to enter the contest in 4 save chances and they have come away with 2 saves. Seattle relief pitchers have an inherited score percentage of 27.3% out of their 11 inherited runners. Their relievers have come in 15 times in high leverage situations in addition to 11 occasions with runners on. They are ranked 25th in the league with a save rate of 50.0%, and they have sent 36 bullpen pitchers to the hill on the season.

In their 1,050 innings on the field, the Mariners hold a efficiency on defense of 71.8% (7th in MLB). The Seattle Mariners have turned 15 double plays and own a fielding percentage of .983 (17th in baseball). The Mariners have racked up 114 assists, 8 errors and have earned 350 putouts during this campaign.

Hancock (9-10 win-loss record in his career) has a 4.54 earned run average while giving up 9.0 hits per 9 innings. He has a K/BB ratio of 2.28 and he has faced 743 opposing hitters in his pro baseball career. He has given up a total of 88 ER's while earning a WHIP of 1.307 and having a FIP of 4.5. So far in his career, Hancock has allowed 174 hits while he has tallied 123 punch outs in 174 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Seattle (+102)

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