Houston Astros vs Tampa Bay Rays Prediction, 9/13/2026 MLB Picks, Best Bets & Odds

Game: Houston Astros vs Tampa Bay Rays

Date: Sunday, September 13, 2026

Location: Tropicana Field in St. Petersburg, FL

TV: MLB.TV

Odds/Point Spread: Houston (+132) Tampa Bay (-160)

The Tampa Bay Rays (87-59) will go up against the Houston Astros (75-72) at Tropicana Field on Sunday. The moneyline on this game has Houston at +132 and Tampa Bay is opening at -160. The over/under is set at 9. The starting pitchers are Hayden Wesneski and Freddy Peralta.

As a squad, the Houston Astros are knocking in 4.5 runs per game, which has them at 14th in baseball. They have accounted for 662 runs scored while holding a team on-base percentage of .315. The Astros have accrued 219 two-baggers as a squad and have hit 193 balls out of the stadium. They have compiled 631 RBI's and 1,191 base knocks this year, and their team batting average is .241. Houston has a slugging percentage of .410 and have been rung up 1,206 times, while being walked on 481 occasions.

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They have a strikeout to walk ratio of 2.17 and their pitching staff has earned a collective WHIP of 1.35. Astros pitchers have relinquished 186 long balls in addition to 702 total runs (24th in baseball). Houston has allowed 1,164 base hits (8.0 per 9 innings) and also 656 earned runs. The Astros hold a team ERA of 4.52 over the course of the season (24th in baseball), and they have struck out 1,291 batters. Their pitching staff has walked 596 batters and their FIP is 4.54 as a team so far this season.

The Astros relievers have compiled a save rate of 81.0% and have come into the game in 139 save situations. They have compiled 47 saves over the course of the season and have blown 11 out of their 58 save opportunities. The relief pitchers have inherited 202 base runners on the season with 26.7% of them crossing home plate. Astros pitchers have entered the contest with players on base 135 times in addition to having 154 appearances in high leverage situations. The Astros have sent 477 relievers to the mound so far this season. The bullpen have racked up 79 holds over the course of the season (17th in the league).

The Houston Astros have notched a total of 3,916 putouts at this point in the season, in addition to 1,080 assists and 66 errors. Their fielding percentage sits at .987 which puts them in 11th in baseball, and they have turned 117 double plays. The Astros have turned 70.6% of balls hit into play into outs out of their 11,748 innings, which has them ranked 11th in MLB.

Wesneski (15-17 career mark) is the owner of a FIP of 3.85 while going up against 1,105 hitters during his time in the majors. He has allowed 224 base knocks (7.5 hits per nine innings) and has 80 free passes. His earned run average is 3.91 (116 earned runs allowed) and he has a career WHIP of 1.138. Wesneski has taken the hill for 267 innings and has accumulated 248 punch outs during his career.

The Rays hold a slugging percentage of .404 and they earn 4.53 runs per outing (12th in MLB). They have 201 two-baggers, while taking a walk 466 times and putting up 662 runs. Tampa Bay has knocked in 155 home runs this year to go along with 630 runs batted in. They have struck out on 1,017 instances (30th in the league) and have earned a total of 1,280 hits. The Tampa Bay Rays hold a team OBP of .329 as well as a batting average of .260 on the season.

The Rays have a team WHIP of 1.146 in addition to having a FIP of 4.07 as a squad on the season. They are currently ranked 5th in the league as a staff in total hits surrendered with 1,127. The Tampa Bay pitching staff have conceded 606 runs this season while holding an ERA of 3.81 (551 earned runs relinquished). They currently have a strikeout to walk ratio of 8.10 (1,177 strikeouts vs 366 walks). They have relinquished 182 dingers and they allow 4.19 runs per 9 innings (7th in the league).

Tampa Bay relief pitchers have an inherited score rate of 33.7% out of 178 inherited base runners. Their relief pitchers have taken the field 145 times in high leverage situations in addition to 124 occasions with runners on. With 181 save situations, the Rays have accrued 107 holds in addition to 18 blown saves. They rank 4th in the league with a save rate of 75.3%, and they have dispatched 465 relief pitchers onto the field this season.

The Tampa Bay Rays have gotten 92 double plays and have a fielding percentage of .983 (24th in the majors). The Rays have accrued 1,159 assists, 87 errors and have amassed 3,909 putouts this year. In 11,727 innings on the diamond, the Rays have earned a defensive efficiency of 72.1% (1st in MLB).

In his pro baseball career, Peralta has surrendered 727 base knocks while earning 1,182 punch outs in 970 innings. He has conceded a total of 390 ER's while holding a WHIP of 1.128 and being the owner of a FIP of 3.6. His strikeout to walk ratio is 3.22 and he has faced 4,008 batters so far in his career. Peralta (73-44 career record) holds a 3.62 earned run average and has given up 6.7 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Houston (+132)

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