Los Angeles Dodgers vs Houston Astros Prediction, 5/4/2026 MLB Picks, Best Bets & Odds

Game: Los Angeles Dodgers vs Houston Astros

Date: Monday, May 4, 2026

Location: Daikin Park in Houston, TX

TV: Space City Home Network

Odds/Point Spread: Los Angeles (-160) Houston (+132)

The Houston Astros (13-21) will try to beat the Los Angeles Dodgers (20-13) at Daikin Park on Monday. The line on this contest has Los Angeles at -160 and Houston is priced at +132. The over/under has been set at 9. The starting pitchers will be Yoshinobu Yamamoto and Colton Gordon.

The Dodgers have hit 53 two-baggers as a squad and have hit 45 balls out of the park. Los Angeles is slugging .442 and have been called out on strikes 263 times, while drawing a walk on 130 occasions. As a team, the Los Angeles Dodgers are compiling 5.2 runs per game, which has them at 6th in the league. They have 163 RBI's in addition to 301 base knocks on the year, and their average at the plate is sitting at .271. They have earned 171 runs scored while holding a team on-base percentage of .349.

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The Dodgers have compiled a team earned run average of 3.29 on the year (3rd in the league), and the staff has struck out 293 batters. Dodgers pitchers have surrendered 30 home runs and 111 total runs (1st in the league). Their pitching staff has walked 101 hitters and their FIP sits at 3.66 as a team on the season. Los Angeles has relinquished 228 base knocks (7.1 per 9 innings) as well as 106 earned runs. Their strikeout to walk ratio is 2.90 and their pitching staff has earned a collective WHIP of 1.13.

The Dodgers have dispatched 99 relief pitchers to the hill on the year. The relief pitchers have inherited 33 runners on the campaign with 24.2% of those runners crossing the plate. The bullpen have racked up 16 holds on the season (21st in MLB). Dodgers bullpen pitchers have entered the game with opponents on base 19 times and also have had 30 appearances in high leverage situations. They have recorded 7 saves on the season and have missed out on 5 of their 12 save opportunities. The Dodgers relief pitchers have earned a save rate of 58.3% and stepped onto the hill in 28 save situations.

The Los Angeles Dodgers have accumulated 870 putouts at this point in the season, as well as 265 assists and 12 errors. Their fielding percentage sits at .990 which is 5th in MLB, and have a total of 20 double plays. The Dodgers have turned 72.6% of balls hit into play into outs out of their 2,610 innings, which has them sitting at 3rd in MLB.

Yamamoto (21-12 win-loss mark in his career) holds a FIP of 2.66 and he has gone up against 1,199 opposing hitters during his time in the major leagues. He has allowed 220 base hits (6.6 hits per 9 innings) with 90 walks. His earned run average is 2.70 (90 earned runs allowed) and his career WHIP is 1.032. Yamamoto has taken the mound for 300 innings and is sitting with 338 strikeouts during his pro baseball career.

Houston has accounted for 43 home runs on the year as well as 166 runs batted in. They have put up 71 doubles, while taking a walk 132 times and scoring 175 runs. The Houston Astros have accumulated an OBP of .347 in addition to a team batting average of .269 over the course of the season. The Astros have a SLG% of .442 and they are recording 5.15 runs per contest (7th in the league). They have been called out on strikes on 260 instances (25th in the league) and have recorded 315 base knocks.

The Houston pitching staff have surrendered 200 runs this season while having an ERA of 5.92 (194 earned runs conceded). They have conceded 47 long balls and they relinquish 6.10 runs per 9 innings (30th in the league). The Astros hold a team WHIP of 1.633 and are the owners of a FIP of 5.24 as a squad on the season. Their K/BB ratio is 9.30 (304 strikeouts vs 183 bases on balls). They come in at 26th in baseball as a staff in total hits conceded with 299.

With 21 save situations, the Astros have earned 13 holds and 1 blown save. Houston has had bullpen pitchers enter the game in 8 save opportunities and they have come away with 7 saves. Houston relief pitchers have an inherited score percentage of 30.4% out of their 69 inherited base runners. Their relief pitchers have taken the field 24 times in high leverage situations and on 41 occasions with runners on. They are currently ranked 1st in baseball with a save rate of 87.5%, and they have dispatched 109 bullpen pitchers onto the diamond over the course of the season.

The Houston Astros have turned 35 double plays and have notched a fielding percentage of .990 (4th in pro baseball). The Astros have accrued 258 assists, 11 errors and have notched a total of 886 putouts for the season. Out of their 2,658 innings on the field, the Astros are sitting with a defensive efficiency of 67.4% (28th in MLB).

So far in his career, Gordon has surrendered 124 base hits while he has earned 83 strikeouts in 95 innings. He has surrendered 63 ER's while earning a WHIP of 1.535 and a FIP of 5.9. He has a strikeout to walk ratio of 3.77 and he has gone up against 429 batters so far in his pro baseball career. Gordon (6-4 career win-loss mark) has earned a 5.96 ERA and has allowed 11.7 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Houston (+132)

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