Los Angeles Dodgers vs Houston Astros Prediction, 5/5/2026 MLB Picks, Best Bets & Odds

Game: Los Angeles Dodgers vs Houston Astros

Date: Tuesday, May 5, 2026

Location: Daikin Park in Houston, TX

TV: Space City Home Network

Odds/Point Spread: Los Angeles (-144) Houston (+120)

Daikin Park is the site where the Houston Astros (14-21) will try to beat the Los Angeles Dodgers (21-13) on Tuesday. The moneyline on this matchup has Los Angeles at -144 while Houston is at +120. The betting total comes in at 8. The pitchers who are expected to start will be Shohei Ohtani and Peter Lambert.

The Dodgers have earned 56 two-baggers as a team and have hit 45 balls out of the park. Los Angeles is slugging .440 and have struck out 268 times, while taking a walk on 134 occasions. As a team, the Los Angeles Dodgers are notching 5.2 runs per game, which has them at 5th in MLB. They have amassed 167 runs batted in in addition to 311 base knocks for the year, while their team batting average is .271. They have accounted for 175 runs and have an OBP of .350.

Get all of our MLB Picks

Their strikeout to walk ratio sits at 2.86 and their pitching staff has earned a collective WHIP of 1.13. Dodgers pitchers have given up 30 home runs in addition to 112 total runs (1st in the league). Los Angeles has yielded 235 hits (7.1 per 9 innings) and also 107 earned runs. The Dodgers hold a team earned run average of 3.22 on the season (3rd in the league), and they have rung up 295 hitters. They have walked 103 opposing batters and their FIP comes in at 3.65 as a team so far this year.

The Dodgers have sent 102 relievers to the hill on the season. The relief pitchers have inherited 34 base runners so far this season with 23.5% of those runners ended up crossing the plate. The bullpen have 18 holds so far this year (19th in MLB). Dodgers pitchers have entered the game with runners on base 20 times as well as having 30 appearances in high leverage situations. They have earned 8 saves this season and have missed out on 5 of their 13 save opportunities. The Dodgers relief pitchers have a save rate of 61.5% and have come into the game in 31 save situations.

The Dodgers have turned 72.7% of baseballs in play into outs in their 2,691 innings on the field, which has them sitting at 3rd in the majors. The Los Angeles Dodgers have notched a total of 897 putouts at this point in the season, in addition to 275 assists and 13 errors. Their fielding rate is currently at .989 which has them ranked 5th in MLB, and have accumulated 21 double plays.

Ohtani has taken the hill for 558 innings and has accounted for 704 K's thus far in his career. His earned run average is 2.87 (178 earned runs allowed) and his career WHIP is 1.068. He has given up 405 hits (6.5 hits per nine innings) with 191 walks. Ohtani (41-21 record in his career) sits with a FIP of 2.83 while he has faced 2,258 hitters during his time in the majors.

Houston has a total of 43 home runs for the season to go along with 169 RBIs. They have put up 73 two-baggers, while walking 137 times and scoring 178 runs. The Houston Astros have an on-base percentage of .348 as well as a team batting average of .269 so far this season. The Astros hold a slugging percentage of .440 and they earn 5.09 runs per outing (8th in MLB). They have struck out on 269 occasions (23rd in MLB) and have a total of 325 hits.

The Astros have a team WHIP of 1.622 in addition to having a FIP of 5.20 as a staff for the season. They currently have a strikeout to walk ratio of 9.30 (315 strikeouts against 187 walks). They come in at 26th in the league as a staff in total hits conceded with 308. They have allowed 48 homers and they allow 5.93 runs per 9 innings (30th in the league). The Houston pitching staff have allowed 201 runs this season while holding an ERA of 5.75 (195 earned runs relinquished).

Sitting with 21 save situations, the Astros have amassed 13 holds and 1 blown save. Houston has had bullpen pitchers step onto the hill in 8 save opportunities and they have earned 7 saves. Houston relievers have an inherited score percentage of 29.6% out of their 71 inherited runners. Their relievers have taken the field 28 times in high leverage situations and on 42 occasions with runners on. They are currently ranked 1st in the league holding a save percentage of 87.5%, and they have dispatched 113 relief pitchers to the mound so far this season.

In their 2,748 innings played, the Astros hold a efficiency on defense of 67.3% (28th in the majors). The Houston Astros have gotten 36 double plays and have a fielding percentage of .990 (4th in baseball). The Astros have recorded 265 assists, 12 errors and have amassed 916 putouts on the season.

So far in his career, Lambert has conceded 309 hits and he has 200 punch outs in 258 frames. Lambert (9-21 career win-loss record) has a 6.13 ERA and has conceded 10.8 hits per nine innings. He has given up 176 earned runs while earning a WHIP of 1.591 and having a FIP of 6.0. He has a strikeout to walk ratio of 1.96 and he has faced 1,171 batters in his career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Houston (+120)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here

Get MLB picks on every single game, or if you want our very best bets by the experts, sign up for your free $60 account with a guarantee.