Los Angeles Dodgers vs San Francisco Giants Prediction, 9/27/2026 MLB Picks, Best Bets & Odds

Game: Los Angeles Dodgers vs San Francisco Giants

Date: Sunday, September 27, 2026

Location: Oracle Park in San Francisco, CA

TV: NBC Bay Area

Odds/Point Spread: Los Angeles (-144) San Francisco (+120)

The San Francisco Giants (65-94) welcome the Los Angeles Dodgers (97-62) at Oracle Park on Sunday. The odds on this game have Los Angeles at -144 while San Francisco is sitting at +120. The betting total is set at 9. The pitchers who are expected to start are Justin Wrobleski and Anthony Molina.

The Dodgers have tallied 262 doubles as a team and have hit 199 balls out of the park. Los Angeles is slugging .425 and have struck out 1,243 times, while taking a walk on 618 occasions. As a unit, the Los Angeles Dodgers are scoring 5.0 runs per game, which has them sitting at 4th in MLB. They have compiled 745 runs batted in and 1,375 base knocks so far this year, while their average at the plate is sitting at .257. They have earned 790 runs while having a team on-base percentage of .339.

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They have accumulated a K/BB ratio of 3.10 and their pitching staff has earned a collective WHIP of 1.15. Dodgers pitchers have yielded 172 long balls and also 596 total runs (2nd in the league). Los Angeles has surrendered 1,142 hits (7.3 per 9 innings) and also 562 earned runs. The Dodgers hold a team ERA of 3.59 so far this year (4th in the league), and their staff has struck out 1,481 batters. They have walked 477 players from the other team and their FIP comes in at 3.74 as a team this year.

The Dodgers have sent 525 relief pitchers to the hill on the year. The bullpen pitchers have inherited 179 runners for the season with 35.8% of them ended up scoring. The relief pitchers have recorded 99 holds this season (7th in baseball). Dodgers relief pitchers have stepped onto the hill with runners on base 111 times in addition to having 167 appearances in high leverage situations. They have 44 saves so far this year and have not converted 22 out of their 66 save chances. The Dodgers relief pitchers have recorded a save rate of 66.7% and have stepped onto the mound in 166 save situations.

The Dodgers have converted 72.1% of balls in play into outs out of their 12,669 innings on the diamond, which has them ranked 2nd in pro baseball. The Los Angeles Dodgers are sitting with 4,223 putouts at this point in the season, in addition to 1,269 assists and 64 errors. Their fielding percentage sits at .988 which has them ranked 4th in pro baseball, and have a total of 88 double plays.

Wrobleski has taken the mound for 241 frames and has tallied 217 strikeouts during his pro baseball career. Wrobleski (18-12 mark in his career) holds a FIP of 4.12 while he has faced 1,005 opposing batters during his time in the majors. His earned run average is 4.18 (112 earned runs allowed) and his WHIP is 1.203. He has conceded 226 hits (8.4 hits per nine innings) and has 64 walks.

The San Francisco Giants are sitting with an OBP of .308 as well as a batting average of .246 on the campaign. They have struck out on 1,302 instances (19th in MLB) and are sitting with 1,324 base knocks. San Francisco has hit 178 HRs on the year as well as 642 RBIs. The Giants hold a slugging % of .403 and they score 4.18 runs per game (24th in the league). They have notched 258 two-baggers, while taking a walk 446 times as well as earning 665 runs.

The Giants have a WHIP of 1.360 with a FIP of 4.24 as a pitching staff so far this season. They currently have a K/BB ratio of 7.60 (1,180 strikeouts against 586 free passes). They are sitting at 18th in baseball as a staff in total hits given up with 1,321. They have surrendered 155 homers and they surrender 4.81 runs per 9 innings (23rd in baseball). The San Francisco pitching staff have conceded 749 runs on the season while having a team ERA of 4.36 (679 earned runs given up).

They sit at 27th in MLB with a save percentage of 53.6%, and they have sent 509 bullpen pitchers to the mound on the year. Their bullpen pitchers have taken the field 138 times in high leverage situations and on 182 occasions with runners on. With 139 save situations, the Giants have accrued 83 holds in addition to 26 blown saves. San Francisco has called on relievers to step onto the mound in 56 save opportunities and they have earned 30 saves. San Francisco relief pitchers have an inherited score percentage of 34.6% out of 283 inherited base runners.

Out of their 12,618 innings on the field, the Giants have a efficiency on defense of 69.6% (15th in pro baseball). The San Francisco Giants have turned 143 double plays and have earned a fielding percentage of .982 (30th in professional baseball). The Giants have recorded 1,489 assists, 106 errors and have a tally of 4,206 putouts so far this season.

Thus far in his career, Molina has given up 130 base knocks and he has 67 K's in 99 frames. Molina (2-2 career mark) holds a 6.90 earned run average while giving up 11.8 hits per nine innings. He has allowed 76 ER's while holding a WHIP of 1.604 and a FIP of 6.8. He has a K/BB ratio of 2.31 and he has faced 445 hitters in his career.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take San Francisco (+120) and under 9 runs

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