Miami Marlins vs San Diego Padres Prediction, 9/20/2026 MLB Picks, Best Bets & Odds

Game: Miami Marlins vs San Diego Padres

Date: Sunday, September 20, 2026

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Miami (+110) San Diego (-130)

Petco Park is the site where the San Diego Padres (84-69) will attempt to beat the Miami Marlins (76-77) on Sunday. The moneyline on this game has Miami at +110 while San Diego is at -130. The total is 8. The expected starting pitchers will be Sandy Alcantara and Walker Buehler.

As a squad, the Miami Marlins are recording 4.5 runs per contest, which is 17th in the league. They have accumulated 681 runs and have an on-base percentage of .327. The Marlins have earned 234 doubles as a team and have hit 157 baseballs out of the stadium. They have accrued 651 RBI's in addition to 1,272 base knocks over the course of the season, and their team batting average is at .249. Miami is slugging .401 and have been rung up 1,269 times, while taking a walk on 524 occasions.

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The Marlins are sitting with a team earned run average of 4.10 on the year (14th in the league), and the staff has rung up 1,238 hitters. Marlins pitchers have conceded 160 home runs in addition to 673 runs in total (12th in the league). They have walked 532 opposing batters and their FIP sits at 4.16 as a unit so far this year. Miami has surrendered 1,196 hits (8.0 per 9 innings) and also 613 earned runs. They have accrued a K/BB ratio of 2.33 and the pitching staff holds a WHIP of 1.28.

The Marlins bullpen have compiled a save rate of 62.3% and have entered the game in 144 save situations. They have earned 33 saves on the campaign and have blown 20 of their 53 chances to save the game. The bullpen pitchers have inherited 194 runners so far this year and 27.8% of those runners crossing home plate. Marlins pitchers have entered the game with players on base 137 times and also have had 150 appearances in high leverage situations. The Marlins have sent 510 relief pitchers to the mound on the season. The relief pitchers have accumulated 88 holds this season (11th in the league).

The Miami Marlins have accounted for 4,041 putouts at this point in the season, in addition to 1,279 assists and 95 errors. Their fielding percentage sits at .982 which has them ranked 27th in pro baseball, and have a total of 108 double plays. The Marlins have turned 70.6% of baseballs in play into outs out of 12,123 innings, which has them sitting 11th in MLB.

Alcantara (65-77 mark in his career) has earned a FIP of 3.63 while he has faced 5,286 opposing batters during his time in the majors. He has allowed 1,129 base knocks (7.9 hits per nine innings) with 388 walks. His earned run average is 3.68 (524 ER's allowed) and he has a career WHIP of 1.184. Alcantara has taken the mound for 1,281 innings and has accumulated 1,080 strikeouts in his pro baseball career.

The Padres have a team slugging % of .397 and they score 4.37 runs per contest (20th in MLB). They have put up 223 two-baggers, while getting a free base 526 times and notching 668 runs. San Diego has compiled 172 home runs on the year to go along with 644 runs batted in. They have been called out on strikes on 1,230 occasions (22nd in MLB) and have notched a total of 1,228 base knocks. The San Diego Padres have earned a team OBP of .318 in addition to a batting average of .242 so far this season.

The San Diego pitching staff have allowed 638 runs so far this year while having a team ERA of 3.95 (594 earned runs surrendered). They have given up 170 long balls and they yield 4.24 runs per 9 innings (9th in the league). The Padres have a team WHIP of 1.286 in addition to having a FIP of 4.17 as a staff on the season. Their strikeout to walk ratio sits at 8.20 (1,240 strikeouts against 515 free passes). They have a ranking of 13th in the league as a pitching staff in total hits surrendered with 1,228.

With 167 save situations, the Padres have amassed 98 holds in addition to 18 blown saves. San Diego has had relief pitchers step onto the mound in 65 save chances and they have tallied 47 saves. San Diego bullpen pitchers have an inherited score rate of 31.9% out of 238 inherited runners. Their bullpen pitchers have stepped onto the mound 181 times in high leverage situations and on 146 occasions with runners on. They rank 6th in the league with a save rate of 72.3%, and they have dispatched 516 relievers to the hill for the year.

In their 12,198 innings played, the Padres are sitting with a defensive efficiency of 70.7% (10th in MLB). The San Diego Padres have turned 122 double plays and hold a fielding percentage of .989 (4th in MLB). The Padres have racked up 1,358 assists, 63 errors and have earned 4,066 putouts on the season.

Thus far in his career, Buehler has surrendered 860 base knocks while earning 968 K's in 982 innings pitched. Buehler (65-35 career record) holds a 3.67 ERA while allowing 7.9 hits per nine innings. He has allowed 401 earned runs while holding a WHIP of 1.186 and a FIP of 3.6. He has a K/BB ratio of 3.17 and he has gone up against 4,076 opposing hitters so far in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Miami (+110)

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