Milwaukee Brewers vs Baltimore Orioles Prediction, 9/20/2026 MLB Picks, Best Bets & Odds

Game: Milwaukee Brewers vs Baltimore Orioles

Date: Sunday, September 20, 2026

Location: Oriole Park at Camden Yards in Baltimore, MD

TV: MASN

Odds/Point Spread: Milwaukee (-150) Baltimore (+125)

Oriole Park at Camden Yards is the site where the Baltimore Orioles (75-78) will attempt to beat the Milwaukee Brewers (95-58) on Sunday. The odds on this game have Milwaukee at -150 while Baltimore is sitting at +125. The total is 8.5. The expected starting pitchers will be Jacob Misiorowski and Brandon Young.

The Brewers have recorded 268 two-baggers as a unit and have hit 147 baseballs out of the park. Milwaukee is slugging .405 and have struck out 1,288 times, while drawing a walk on 635 occasions. As a team, the Milwaukee Brewers are notching 5.2 runs/g, which has them at 2nd in MLB. They have 748 runs batted in as well as 1,350 hits so far this year, while their team batting average sits at .259. They have a total of 792 runs while holding a team on-base percentage of .342.

Get all of our MLB Parlay Picks

The Brewers have compiled a team ERA of 3.58 over the course of the season (2nd in the league), and the staff has struck out 1,467 batters. Brewers pitchers have allowed 164 home runs in addition to 595 total runs (5th in baseball). Their pitching staff has walked 491 players from the other team and their FIP is 3.72 as a team for the season. Milwaukee has conceded 1,135 base knocks (7.5 per 9 innings) as well as 543 earned runs. Their strikeout to walk ratio is 2.99 and their pitching staff sits with a WHIP of 1.19.

The Brewers relievers have accumulated a save rate of 71.6% and have come into the game in 146 save situations. They have recorded 48 saves for the year and have blown 19 of their 67 save opportunities. The relief pitchers have inherited 179 base runners on the year and 39.1% of those players ended up scoring. Brewers pitchers have gone to the mound with players on base 123 times in addition to having 148 appearances in high leverage situations. The Brewers have dispatched 476 relievers to the mound on the year. The relief pitchers have earned 78 holds on the campaign (21st in the league).

The Brewers have converted 70.9% of balls in play into outs out of 12,291 innings, which has them sitting at 8th in MLB. The Milwaukee Brewers have a total of 4,097 putouts so far this season, in addition to 1,198 assists and 68 errors. Their fielding rate is holding at .987 which puts them in 9th in pro baseball, and have a total of 114 double plays.

Misiorowski has taken the hill for 232 innings and has totaled 330 K's in his career. His earned run average is 2.60 (67 earned runs allowed) and his career WHIP is 0.935. He has allowed 144 hits (5.6 hits per nine innings) and has 73 free passes. Misiorowski (20-8 career mark) has a FIP of 2.56 while he has faced 909 batters during his time in the majors.

The Orioles have a slugging percentage of .396 and they have an average of 4.50 runs per contest (13th in MLB). They have recorded 224 doubles, while getting a free base 560 times and putting up 688 runs. Baltimore has knocked in 188 home runs over the course of the season as well as 663 RBIs. They have struck out on 1,439 instances (3rd in the league) and have earned 1,198 hits. The Baltimore Orioles are sitting with an OBP of .315 in addition to a batting average of .234 on the campaign.

The Baltimore pitching staff have relinquished 714 runs on the year and come in with a team ERA of 4.14 (628 earned runs yielded). They have allowed 166 home runs and they allow 4.71 runs per 9 innings (22nd in MLB). The Orioles hold a team WHIP of 1.347 and have a FIP of 4.10 as a pitching staff on the year. They have earned a K/BB ratio of 8.10 (1,229 strikeouts vs 509 bases on balls). They rank 28th in MLB as a staff in total hits surrendered with 1,328.

Baltimore relievers have an inherited score percentage of 26.8% out of their 213 inherited runners. Their relievers have stepped onto the mound 164 times in high leverage situations and on 156 occasions with base runners. With 149 save situations, the Orioles have 80 holds in addition to 22 blown saves. They are ranked 12th in baseball holding a save rate of 66.7%, and they have dispatched 515 relievers to the mound over the course of the season.

In 12,279 innings on the diamond, the Orioles have accumulated a defensive efficiency of 68.8% (27th in professional baseball). The Baltimore Orioles have gotten 114 double plays and own a fielding percentage of .983 (23rd in professional baseball). The Orioles have racked up 1,304 assists, 92 errors and have accounted for 4,093 putouts on the campaign.

Young (10-11 win-loss record in his career) has a 4.40 earned run average while allowing 9.4 hits per 9 innings. He has a K/BB ratio of 2.14 and he has faced 885 batters during his pro baseball career. He has surrendered 99 earned runs while earning a WHIP of 1.428 and having a FIP of 4.3. In his pro baseball career, Young has surrendered 212 hits while he has accumulated 165 punch outs in 202 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Milwaukee (-150)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here

Get MLB picks on every single game, or if you want our very best bets by the experts, sign up for your free $60 account with a guarantee.