Milwaukee Brewers vs Chicago Cubs Prediction, 5/20/2026 MLB Picks, Best Bets & Odds

Game: Milwaukee Brewers vs Chicago Cubs

Date: Wednesday, May 20, 2026

Location: Wrigley Field in Chicago, IL

TV: Marquee

Odds/Point Spread: Milwaukee (+150) Chicago (-182)

The Chicago Cubs (29-17) are welcoming the Milwaukee Brewers (26-17) at Wrigley Field on Wednesday. The line on this matchup has Milwaukee at +150 while Chicago is coming in at -182. The over/under is set at 8. The starting pitchers will be Kyle Harrison and Edward Cabrera.

Milwaukee is slugging .360 and have been called out on strikes 351 times, while taking a walk on 193 occasions. They have accounted for 208 runs batted in and 360 base knocks over the course of the season, while their team batting average comes in at .244. The Brewers have hit 74 doubles as a squad and have hit 30 baseballs out of the park. They have accumulated 218 runs while holding a team OBP of .333. As a team, the Milwaukee Brewers are putting up 5.0 runs per contest, which has them sitting at 6th in MLB.

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They have accrued a K/BB ratio of 2.80 and their pitching staff has recorded a WHIP of 1.21. Brewers pitchers have given up 34 home runs and also 157 total runs (3rd in MLB). Milwaukee has allowed 323 base hits (7.4 per 9 innings) in addition to 143 earned runs. The Brewers have compiled a team earned run average of 3.29 over the course of the season (3rd in the league), and the staff has rung up 426 hitters. Their pitching staff has walked 152 opposing batters and their FIP sits at 3.34 as a squad over the course of the season.

Brewers bullpen pitchers have gone to the mound with players on base 36 times as well as having 46 appearances in high leverage situations. The relief pitchers have accumulated 25 holds over the course of the season (15th in MLB). The Brewers relief pitchers have a save rate of 63.6% and stepped onto the hill in 48 save situations. They have accumulated 14 saves for the season and have missed out on 8 of 22 save opportunities. The relief pitchers have inherited 55 base runners on the campaign and 36.4% of those runners earned a run for their team. The Brewers have dispatched 142 relievers to the hill for the year.

The Milwaukee Brewers are sitting with 1,174 putouts at this point in the season, in addition to 343 assists and 20 errors. Their fielding percentage is currently at .987 which puts them in 14th in the majors, and they have turned 33 double plays. The Brewers have turned 69.7% of balls hit into play into outs out of 3,522 innings on the diamond, which has them ranked 19th in the majors.

Harrison has taken the hill for 232 frames and is sitting with 239 punch outs so far in his MLB career. His earned run average is 4.03 (104 ER's allowed) and he has a WHIP of 1.299. He has given up 222 base hits (8.6 hits per nine innings) and has 80 walks. Harrison (13-10 career win-loss record) holds a FIP of 3.97 and he has faced 995 hitters in the major leagues.

Chicago has 57 long balls on the year as well as 222 runs batted in. They have put up 72 doubles, while walking 221 times as well as notching 241 runs. The Chicago Cubs have compiled an on-base percentage of .343 as well as a batting average of .246 over the course of the season. The Cubs have a slugging percentage of .406 and they average 5.13 runs per outing (4th in MLB). They have struck out on 381 occasions (18th in MLB) and have totaled 394 base hits.

The Chicago pitching staff have yielded 199 runs for the year while holding an ERA of 3.99 (185 earned runs allowed). They have surrendered 64 homers and they relinquish 4.29 runs per 9 innings (12th in the league). The Cubs have a WHIP of 1.204 and are the owners of a FIP of 4.37 as a staff on the campaign. They currently have a K/BB ratio of 8.20 (382 strikeouts vs 141 walks). They are sitting at 11th in baseball as a staff in total hits allowed with 361.

Chicago relief pitchers hold an inherited score rate of 28.4% out of their 67 inherited base runners. Their bullpen pitchers have stepped onto the hill 50 times in high leverage situations and also on 48 occasions with runners on base. Sitting with 31 save situations, the Cubs have earned 11 holds and 7 blown saves. They are currently ranked 20th in the league holding a save percentage of 58.8%, and they have sent 140 bullpen pitchers to the mound for the season.

In 3,756 innings on the field, the Cubs hold a efficiency on defense of 72.5% (4th in MLB). The Chicago Cubs have turned 34 double plays and hold a fielding percentage of .988 (12th in baseball). The Cubs have accrued 435 assists, 21 errors and have notched a total of 1,252 putouts on the campaign.

Cabrera (28-30 record in his career) holds a 4.07 earned run average while giving up 7.4 hits per 9 innings. He has a strikeout to walk ratio of 2.24 and he has faced 2,055 batters during his career. He has allowed 218 ER's while earning a WHIP of 1.311 and being the owner of a FIP of 4.0. So far in his MLB career, Cabrera has conceded 398 base hits and he has 523 K's in 482 frames.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Chicago (-182)

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