Milwaukee Brewers vs Chicago Cubs Prediction, 9/2/2026 MLB Picks, Best Bets & Odds

Game: Milwaukee Brewers vs Chicago Cubs

Date: Wednesday, September 2, 2026

Location: Wrigley Field in Chicago, IL

TV: Marquee

Odds/Point Spread: Milwaukee (+126) Chicago (-152)

Wrigley Field is where the Chicago Cubs (78-60) will meet the Milwaukee Brewers (85-53) on Wednesday. The moneyline on this matchup has Milwaukee at +126 while Chicago is opening at -152. The total comes in at 8.5. The pitchers expected to start will be Jacob Misiorowski and David Peterson.

Milwaukee has a slugging rate of .398 and have struck out 1,152 times, while taking a walk on 568 occasions. They have accrued 647 RBI's and 1,194 base knocks on the year, while their average at the plate is at .255. The Brewers have tallied 241 doubles as a unit and have hit 127 baseballs out of the park. They have 686 runs and hold an on-base percentage of .338. As a squad, the Milwaukee Brewers are recording 5.0 runs per contest, which has them at 3rd in MLB.

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The Brewers have an ERA of 3.47 over the course of the season (2nd in the league), and their staff has rung up 1,323 hitters. Brewers pitchers have relinquished 146 long balls and also 523 runs (3rd in baseball). Their pitching staff has walked 437 opposing batters and their FIP is 3.68 as a team on the year. Milwaukee has conceded 1,014 base knocks (7.4 per 9 innings) as well as 476 earned runs. Their strikeout to walk ratio is 3.03 and their pitching staff holds a collective WHIP of 1.18.

The Brewers relief pitchers have recorded a save percentage of 71.0% and have come into the game in 133 save situations. They have tallied 44 saves this year and have missed out on 18 of their 62 save chances. The relief pitchers have inherited 150 base runners on the season and 40.7% of them earned a run for their team. Brewers bullpen pitchers have entered the game with opponents on base 106 times and also have had 131 appearances in high leverage situations. The Brewers have dispatched 418 relievers to the hill on the season. The relief pitchers have recorded 70 holds for the season (20th in MLB).

The Brewers have converted 71.1% of balls hit into play into outs out of their 11,103 innings, ranking them 7th in baseball. The Milwaukee Brewers have a total of 3,701 putouts on the year, in addition to 1,081 assists and 62 errors. Their fielding percentage is at .987 which has them sitting 9th in the majors, and have 104 double plays.

Misiorowski (19-8 mark in his career) sits with a FIP of 2.49 and he has gone up against 844 opposing hitters during his time in the majors. He has surrendered 130 base knocks (5.4 hits per 9 innings) and has 66 free passes. His earned run average is 2.53 (61 ER's allowed) and his career WHIP is 0.903. Misiorowski has taken the hill for 217 innings and has tallied 309 K's during his MLB career.

The Cubs have a team slugging % of .434 and they are recording 5.38 runs per contest (1st in the league). They have recorded 234 doubles, while walking 583 times as well as scoring 742 runs. Chicago has a total of 196 home runs for the year and 701 RBIs. They have been rung up on 1,171 occasions (12th in MLB) and have a total of 1,205 base knocks. The Chicago Cubs hold an OBP of .341 as well as a batting average of .253 on the season.

The Chicago pitching staff have relinquished 601 runs this year while having a team ERA of 4.14 (567 earned runs given up). They have conceded 209 dingers and they allow 4.39 runs per 9 innings (13th in MLB). The Cubs have a team WHIP of 1.255 in addition to having a FIP of 4.69 as a unit this season. They currently have a strikeout to walk ratio of 7.80 (1,068 strikeouts vs 412 walks). They are currently ranked 17th in the league as a pitching staff in total hits given up with 1,136.

Sitting with 107 save situations, the Cubs have accumulated 49 holds in addition to 23 blown saves. Chicago has called on relievers to take the mound in 52 save chances and they have tallied 29 saves. Chicago bullpen pitchers have an inherited score rate of 30.4% of 181 inherited base runners. Their relief pitchers have taken the field 129 times in high leverage situations and on 132 occasions with base runners. They sit at 26th in MLB with a save percentage of 55.8%, and they have sent 441 relievers onto the diamond this year.

The Chicago Cubs have gotten 105 double plays and hold a fielding percentage of .990 (1st in baseball). The Cubs have 1,301 assists, 51 errors and have a tally of 3,701 putouts over the course of the season. Out of their 11,103 innings on the diamond, the Cubs have earned a defensive efficiency of 72.0% (2nd in pro baseball).

So far in his career, Peterson has allowed 646 hits while he has totaled 660 punch outs in 677 frames. Peterson (41-31 career win-loss record) has earned a 4.11 earned run average and has allowed 8.6 hits per nine innings. He has conceded 309 earned runs while earning a WHIP of 1.373 and being the owner of a FIP of 4.0. He has a K/BB ratio of 2.32 and he has faced 2,908 batters so far in his career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Chicago (-152)

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