Milwaukee Brewers vs Cincinnati Reds Prediction, 6/22/2026 MLB Picks, Best Bets & Odds

Game: Milwaukee Brewers vs Cincinnati Reds

Date: Monday, June 22, 2026

Location: Great American Ball Park in Cincinnati, OH

TV: Reds.TV

Odds/Point Spread: Milwaukee (-150) Cincinnati (+125)

The Cincinnati Reds (35-39) will play the Milwaukee Brewers (45-28) at Great American Ball Park on Monday. The moneyline on this contest has the Brewers at -150 and the Reds are priced at +125. The over/under is 8.5. The pitchers who are expected to start will be Brandon Woodruff and Brady Singer.

The Brewers have hit 129 doubles as a team and have knocked 67 baseballs out of the park. Milwaukee has a slugging % of .395 and have been rung up 591 times, while being walked on 314 occasions. As a team, the Milwaukee Brewers are scoring 5.3 runs per contest, which ranks them 3rd in the league. They have amassed 364 RBI's and 632 hits this season, while their batting average sits at .255. They have earned a total of 385 runs scored and hold an OBP of .341.

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Their K/BB ratio is 2.91 and the pitching staff holds a WHIP of 1.20. Brewers pitchers have surrendered 69 long balls in addition to 270 runs (4th in the league). Milwaukee has given up 539 hits (7.4 per 9 innings) in addition to 249 earned runs. The Brewers have a team ERA of 3.43 this season (4th in baseball), and the staff has rung up 718 hitters. Their pitching staff has walked 247 hitters and their FIP sits at 3.53 as a team this season.

The Brewers have dispatched 221 relief pitchers to the hill over the course of the season. The relievers have inherited 87 base runners so far this season with 41.4% of them earned a run for their team. The relievers have a total of 33 holds on the season (23rd in baseball). Brewers pitchers have entered the game with opponents on base 59 times and also have had 66 appearances in high leverage situations. They have recorded 21 saves so far this season and have blown 12 of their 33 save opportunities. The Brewers relievers have compiled a save rate of 63.6% and have come into the game in 67 save situations.

The Milwaukee Brewers have a total of 1,960 putouts so far this season, in addition to 553 assists and 30 errors. Their fielding rate sits at .988 which has them ranked 7th in the majors, and they have turned 57 double plays. The Brewers have converted 70.4% of balls in play into outs in their 5,880 innings on the field, which has them sitting at 11th in professional baseball.

Woodruff has pitched in 775 innings and has 896 punch outs so far in his MLB career. His earned run average is 3.12 (269 earned runs allowed) and he has a career WHIP of 1.034. He has surrendered 604 base hits (7.0 hits per 9 innings) and has had 197 free passes. Woodruff (55-29 win-loss record in his career) holds a FIP of 3.08 while he has gone up against 3,105 opposing hitters in the major leagues.

The Cincinnati Reds have tallied an on-base percentage of .310 in addition to a team batting average of .227 so far this year. They have been called out on strikes on 696 occasions (3rd in MLB) and have totaled 562 base hits. Cincinnati has accounted for 94 home runs this year to go along with 293 runs batted in. The Reds hold a team SLG% of .392 and they are recording 4.20 runs per outing (19th in the league). They have put up 115 doubles, while getting a free base 285 times as well as recording 311 runs.

The Reds are sitting with a team WHIP of 1.471 with a FIP of 5.04 as a pitching staff for the season. Their strikeout to walk ratio is 7.90 (579 strikeouts against 338 free passes). They are sitting at 21st in the league as a pitching staff in total hits relinquished with 633. They have allowed 101 home runs and they concede 5.02 runs per 9 innings (23rd in baseball). The Cincinnati pitching staff have conceded 368 runs this season and come in with a team ERA of 4.66 (342 earned runs yielded).

They are currently ranked 26th in baseball with a save percentage of 53.1%, and they have dispatched 269 relievers to the hill on the year. Their relievers have taken the field 91 times in high leverage situations in addition to 83 occasions with base runners. Sitting with 79 save situations, the Reds have recorded 46 holds and 15 blown saves. Cincinnati has had relievers step onto the mound in 32 save opportunities and they have tallied 17 saves. Cincinnati relief pitchers have an inherited score percentage of 26.7% out of 116 inherited runners.

The Cincinnati Reds have turned 58 double plays and have accounted for a fielding rate of .986 (19th in MLB). The Reds have 616 assists, 37 errors and have amassed 1,980 putouts for the season. In their 5,940 innings on the diamond, the Reds have accumulated a defensive efficiency of 70.4% (13th in professional baseball).

Singer (53-62 win-loss record in his career) has a 4.31 earned run average while allowing 9.1 hits per 9 innings. His strikeout to walk ratio is 2.90 and he has gone up against 3,954 opposing hitters so far in his career. He has allowed 441 earned runs while earning a WHIP of 1.330 and being the owner of a FIP of 4.2. In his pro baseball career, Singer has surrendered 928 base hits while he has accumulated 860 punch outs in 921 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Milwaukee (-150)

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