Milwaukee Brewers vs Cincinnati Reds Prediction, 9/4/2026 MLB Picks, Best Bets & Odds

Game: Milwaukee Brewers vs Cincinnati Reds

Date: Friday, September 4, 2026

Location: Great American Ball Park in Cincinnati, OH

TV: Reds.TV

Odds/Point Spread: Milwaukee (-160) Cincinnati (+132)

Great American Ball Park is the site where the Cincinnati Reds (67-73) will go up against the Milwaukee Brewers (87-53) on Friday. The line on this contest has Milwaukee at -160 while Cincinnati is at +132. The total comes in at 8. The starting pitchers will be Shane Drohan and Rhett Lowder.

Milwaukee has a slugging percentage of .400 and have struck out 1,166 times, while being walked on 578 occasions. They have compiled 664 runs batted in as well as 1,221 base knocks on the year, and their batting average sits at .257. The Brewers have accrued 246 two-baggers as a unit and have hit 130 balls out of the park. They have notched a total of 704 runs scored while having a team OBP of .340. As a team, the Milwaukee Brewers are putting up 5.0 runs per contest, which ranks them 3rd in the league.

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The Brewers have a team ERA of 3.48 on the campaign (2nd in baseball), and they have struck out 1,340 batters. Brewers pitchers have conceded 147 home runs and 532 runs (2nd in baseball). Their pitching staff has walked 445 players from the other team and their FIP sits at 3.68 as a unit over the course of the season. Milwaukee has yielded 1,026 hits (7.4 per 9 innings) and 484 earned runs. Their strikeout to walk ratio is 3.01 and their pitching staff holds a WHIP of 1.18.

The Brewers relief pitchers have a save percentage of 71.0% and have come into the game in 138 save situations. They have accumulated 44 saves for the year and have not converted 18 of their 62 save opportunities. The relief pitchers have inherited 152 runners this season with 40.8% of them crossing the plate. Brewers bullpen pitchers have come into the game with runners on base 108 times and also have had 135 appearances in high leverage situations. The Brewers have dispatched 428 relief pitchers to the hill on the campaign. The relief pitchers are sitting with 75 holds so far this year (16th in the league).

The Milwaukee Brewers have earned a total of 3,755 putouts thus far, in addition to 1,102 assists and 64 errors. Their fielding percentage is holding at .987 which ranks 9th in baseball, and have accumulated 105 double plays. The Brewers have transformed 71.1% of baseballs in play into outs in their 11,265 innings on the diamond, ranking them 7th in MLB.

Drohan has pitched in 110 frames and has accumulated 110 K's thus far in his career. His earned run average is 3.76 (46 earned runs allowed) and he has a WHIP of 1.299. He has given up 106 base knocks (8.7 hits per 9 innings) and has had 37 walks. Drohan (7-5 win-loss mark in his career) has a FIP of 3.70 while he has gone up against 466 batters in the major leagues.

The Reds hold a team slugging % of .396 and they score 4.15 runs per game (24th in MLB). They have put up 197 doubles, while walking 499 times as well as scoring 581 runs. Cincinnati is sitting with 186 HRs this year and 557 runs batted in. They have struck out on 1,329 occasions (2nd in baseball) and have recorded 1,064 base hits. The Cincinnati Reds hold a team on-base percentage of .307 in addition to a team batting average of .228 on the season.

The Reds are sitting with a team WHIP of 1.424 and have a FIP of 4.71 as a team on the season. They sit at 24th in baseball as a staff in total hits allowed with 1,201. The Cincinnati pitching staff have allowed 689 runs over the course of the season while holding an ERA of 4.64 (641 earned runs relinquished). Their K/BB ratio is 8.20 (1,129 strikeouts vs 567 free passes). They have conceded 180 long balls and they relinquish 4.99 runs per 9 innings (25th in the league).

With 138 save situations, the Reds have compiled 77 holds and 21 blown saves. Cincinnati has had relief pitchers enter the game in 58 save chances and they have earned 37 saves. Cincinnati bullpen pitchers have an inherited score percentage of 27.5% out of their 218 inherited base runners. Their relief pitchers have come in 171 times in high leverage situations and on 149 occasions with runners on base. They rank 15th in baseball with a save rate of 63.8%, and they have sent 492 relievers onto the field for the year.

In 11,178 innings played, the Reds have accumulated a efficiency on defense of 69.7% (16th in MLB). The Cincinnati Reds have gotten 96 double plays and have a fielding rate of .984 (19th in professional baseball). The Reds have racked up 1,125 assists, 78 errors and have accumulated 3,726 putouts so far this year.

So far in his career, Lowder has surrendered 145 base hits and he has 110 strikeouts in 142 frames. He has given up a total of 68 ER's while earning a WHIP of 1.421 and a FIP of 4.2. His K/BB ratio is 1.93 and he has faced 627 batters during his career. Lowder (8-10 record in his career) holds a 4.30 earned run average while giving up 9.2 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Milwaukee (-160)

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