Milwaukee Brewers vs Minnesota Twins Prediction, 5/16/2026 MLB Picks, Best Bets & Odds

Game: Milwaukee Brewers vs Minnesota Twins

Date: Saturday, May 16, 2026

Location: Target Field in Minneapolis, MN

TV: Twins.TV

Odds/Point Spread: Milwaukee (-122) Minnesota (+102)

The Minnesota Twins (20-24) will try to beat the Milwaukee Brewers (24-17) at Target Field on Saturday. The moneyline on this matchup has the Brewers at -122 while the Twins are sitting at +102. The over/under is set at 8.5. The pitchers taking the mound are Logan Henderson and Connor Prielipp.

As a unit, the Milwaukee Brewers are scoring 5.1 runs per game, which is 3rd in the league. They have a total of 209 runs and hold an on-base percentage of .336. The Brewers have hit 68 two-baggers as a team and have hit 27 balls out of the park. They have 201 runs batted in as well as 336 hits on the campaign, while their average at the plate sits at .245. Milwaukee has a slugging % of .359 and have been called out on strikes 329 times, while drawing a walk on 184 occasions.

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The Brewers have an earned run average of 3.35 on the year (3rd in baseball), and their staff has struck out 402 hitters. Brewers pitchers have conceded 32 home runs in addition to 149 runs in total (2nd in MLB). They have walked 147 opposing batters and their FIP sits at 3.35 as a unit so far this season. Milwaukee has conceded 302 base hits (7.4 per 9 innings) and also 136 earned runs. Their strikeout to walk ratio is 2.73 and the pitching staff holds a collective WHIP of 1.23.

The Brewers have sent 135 relievers to the mound this season. The relievers have inherited 53 base runners on the campaign and 35.8% of those players crossing the plate. The relief pitchers have notched 24 holds on the campaign (14th in MLB). Brewers pitchers have entered the game with runners on 35 times in addition to having 42 appearances in high leverage situations. They have compiled 12 saves on the season and have blown 7 out of their 19 save chances. The Brewers bullpen have a save percentage of 63.2% and have stepped onto the mound in 44 save situations.

The Brewers have turned 69.6% of baseballs in play into outs out of their 3,288 innings, ranking them 21st in professional baseball. The Milwaukee Brewers have earned a total of 1,096 putouts this year, in addition to 324 assists and 18 errors. Their fielding percentage is holding steady at .987 which ranks 14th in MLB, and they have turned 31 double plays.

Henderson (3-1 mark in his career) has a FIP of 2.56 and he has gone up against 148 opposing hitters in the majors. He has given up 27 hits (6.4 hits per 9 innings) and has 10 walks. His ERA is 2.60 (11 earned runs allowed) and he has a career WHIP of 0.971. Henderson has thrown 38 frames and is sitting with 49 K's so far in his pro baseball career.

Minnesota is sitting with 49 home runs on the season as well as 200 RBIs. They have put up 67 doubles, while getting a free base 173 times and notching 211 runs. The Minnesota Twins have earned a team on-base percentage of .325 and a team batting average of .236 over the course of the season. The Twins hold a slugging percentage of .385 and they have an average of 4.80 runs per game (8th in baseball). They have struck out on 388 instances (8th in the league) and have a total of 347 hits.

The Minnesota pitching staff have surrendered 216 runs for the year while having an ERA of 4.49 (193 earned runs given up). They have yielded 40 homers and they give up 5.02 runs per 9 innings (25th in the league). The Twins have a WHIP of 1.357 in addition to having a FIP of 4.20 as a pitching staff so far this season. Their K/BB ratio sits at 7.70 (332 strikeouts against 162 walks). They are sitting at 20th in baseball as a pitching staff in total hits conceded with 363.

They sit at 18th in MLB holding a save percentage of 61.5%, and they have sent 144 relievers onto the field on the year. Their relievers have taken the field 38 times in high leverage situations and on 49 occasions with runners on base. With 39 save situations, the Twins have 26 holds and also 5 blown saves. Minnesota has called on relief pitchers to step onto the hill in 13 save chances and they have earned 8 saves. Minnesota bullpen pitchers have an inherited score percentage of 38.6% of 70 inherited base runners.

The Minnesota Twins have turned 34 double plays and hold a fielding percentage of .985 (20th in the majors). The Twins have accrued 334 assists, 22 errors and are sitting with 1,161 putouts for the season. Out of their 3,483 innings played, the Twins have accumulated a efficiency on defense of 69.9% (18th in MLB).

Prielipp (1-1 win-loss record in his career) has earned a 3.32 ERA and has given up 5.7 hits per 9 innings. He has a K/BB ratio of 3.00 and he has gone up against 79 opposing hitters during his MLB career. He has given up 7 earned runs while earning a WHIP of 1.000 and a FIP of 3.3. So far in his pro baseball career, Prielipp has surrendered 12 hits while totaling 21 strikeouts in 19 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Minnesota (+102)

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