Milwaukee Brewers vs San Diego Padres Prediction, 10/6/2026 MLB Picks, Best Bets & Odds

Game: Milwaukee Brewers vs San Diego Padres

Date: Tuesday, October 6, 2026

Location: Petco Park in San Diego, CA

TV: FS1

Odds/Point Spread: Milwaukee (+113) San Diego (-136)

The Milwaukee Brewers (103-59) are en route to Petco Park on Tuesday where they will attempt to beat the San Diego Padres (91-71) in Game 3 of the NLDS. Milwaukee leads 2-0. The moneyline on this contest has the Brewers at +113 and the Padres open at -136. The total comes in at 7. The starting pitchers will be Dustin May and Nick Pivetta.

Milwaukee is slugging .403 and have struck out 1,383 times, while drawing a walk on 668 occasions. They have 788 runs batted in and 1,422 hits this season, and their batting average sits at .258. The Brewers have accrued 279 doubles as a unit and have hit 154 balls out of the park. They have accumulated 832 runs scored while holding a team on-base percentage of .341. As a squad, the Milwaukee Brewers are notching 5.1 runs/g, which has them sitting at 2nd in baseball.

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The Brewers have compiled a team ERA of 3.51 over the course of the season (2nd in the league), and their staff has struck out 1,544 hitters. Brewers pitchers have surrendered 171 home runs and also 618 runs in total (4th in the league). They have walked 518 opposing batters and their FIP sits at 3.72 as a unit on the season. Milwaukee has conceded 1,186 base hits (7.4 per 9 innings) in addition to 565 earned runs. Their strikeout to walk ratio sits at 2.98 and their pitching staff holds a collective WHIP of 1.18.

The Brewers have sent 509 relievers to the hill on the year. The relievers have inherited 187 base runners over the course of the season and 37.4% of them ended up scoring. The bullpen have earned 86 holds on the campaign (14th in the league). Brewers relief pitchers have entered the game with runners on base 129 times and also have had 158 appearances in high leverage situations. They have earned 55 saves this season and have blown 21 out of their 76 save opportunities. The Brewers relief pitchers have a save percentage of 72.4% and have entered the game in 164 save situations.

The Milwaukee Brewers have earned a total of 4,340 putouts this season, in addition to 1,269 assists and 72 errors. Their fielding percentage is currently at .987 which is 7th in baseball, and have a total of 118 double plays. The Brewers have converted 71.2% of balls hit into play into outs in their 13,020 innings on the diamond, ranking them 6th in baseball.

May (21-22 win-loss record in his career) is the owner of a FIP of 3.99 while he has gone up against 1,518 opposing hitters during his time in the major leagues. He has given up 313 hits (7.8 hits per 9 innings) with 128 walks. His ERA is 4.05 (162 earned runs allowed) and he has a WHIP of 1.224. May has thrown 360 frames and has racked up 335 punch outs during his MLB career.

The Padres hold a slugging % of .398 and they have an average of 4.46 runs per outing (16th in baseball). They have put up 234 doubles, while walking 554 times and putting up 722 runs. San Diego has recorded 183 home runs this season to go along with 696 runs batted in. They have struck out on 1,310 occasions (22nd in baseball) and have tallied 1,314 base hits. The San Diego Padres are sitting with an OBP of .319 in addition to a batting average of .244 for the season.

The Padres have a team WHIP of 1.294 in addition to having a FIP of 4.20 as a squad so far this season. Their strikeout to walk ratio comes in at 8.20 (1,315 strikeouts against 554 walks). They are sitting at 13th in the league as a staff in total hits allowed with 1,304. They have allowed 180 homers and they give up 4.27 runs per 9 innings (9th in baseball). The San Diego pitching staff have allowed 681 runs so far this season and come in with a team ERA of 3.99 (636 earned runs relinquished).

San Diego relievers hold an inherited score percentage of 31.0% out of 248 inherited base runners. Their relief pitchers have stepped onto the hill 185 times in high leverage situations and also on 153 occasions with runners on. With 179 save situations, the Padres have accrued 106 holds and 20 blown saves. They are currently ranked 8th in baseball with a save percentage of 70.6%, and they have dispatched 550 relievers to the mound on the campaign.

Out of their 12,927 innings on the field, the Padres are sitting with a defensive efficiency of 70.6% (11th in baseball). The San Diego Padres have gotten 131 double plays and have earned a fielding percentage of .989 (2nd in the majors). The Padres have accrued 1,431 assists, 64 errors and have earned 4,309 putouts this year.

Pivetta (72-78 win-loss mark in his career) is the owner of a 4.43 earned run average while surrendering 8.2 hits per 9 innings. He has a K/BB ratio of 3.15 and he has faced 5,247 opposing hitters so far in his career. He has given up a total of 613 earned runs while earning a WHIP of 1.260 and a FIP of 4.4. So far in his pro baseball career, Pivetta has allowed 1,134 hits while tallying 1,371 strikeouts in 1,245 innings.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take San Diego (-136) and under 7 runs

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