Milwaukee Brewers vs St. Louis Cardinals Prediction, 5/4/2026 MLB Picks, Best Bets & Odds

Game: Milwaukee Brewers vs St. Louis Cardinals

Date: Monday, May 4, 2026

Location: Busch Stadium in St. Louis, MO

TV: Cardinals.TV

Odds/Point Spread: Milwaukee (-182) St. Louis (+150)

Busch Stadium is where the St. Louis Cardinals (20-13) will try to defeat the Milwaukee Brewers (18-14) on Monday. The odds on this game have Milwaukee at -182 and St. Louis is priced at +150. The total has been set at 8.5. The pitchers taking the mound will be Brandon Sproat and Kyle Leahy.

Milwaukee is slugging .359 and have been called out on strikes 256 times, while taking a walk on 153 occasions. They have accumulated 163 runs batted in and 260 hits so far this year, and their team batting average comes in at .242. The Brewers have tallied 52 two-baggers as a unit and have smacked 22 balls out of the stadium. They are sitting with 170 runs while having a team on-base percentage of .338. As a squad, the Milwaukee Brewers are notching 5.3 runs per game, which is 3rd in baseball.

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The Brewers hold a team earned run average of 3.56 for the year (5th in MLB), and the staff has rung up 300 batters. Brewers pitchers have surrendered 28 home runs and also 124 runs (5th in MLB). They have walked 117 opposing players and their FIP comes in at 3.67 as a unit so far this season. Milwaukee has given up 243 hits (7.7 per 9 innings) as well as 113 earned runs. Their strikeout to walk ratio is 2.56 and the pitching staff holds a collective WHIP of 1.26.

The Brewers relief pitchers have accumulated a save percentage of 66.7% and have stepped onto the mound in 36 save situations. They have tallied 10 saves this season and have not converted 5 out of their 15 chances to get a save. The bullpen pitchers have inherited 47 runners so far this year and 38.3% of those runners crossing the plate. Brewers relief pitchers have gone to the mound with runners on base 30 times as well as having 35 appearances in high leverage situations. The Brewers have sent 108 relief pitchers to the hill this season. The relief pitchers have a total of 20 holds on the season (15th in the league).

The Brewers have transformed 69.6% of balls hit into play into outs out of 2,568 innings on the diamond, which has them sitting 16th in MLB. The Milwaukee Brewers have earned a total of 856 putouts at this point in the season, in addition to 268 assists and 15 errors. Their fielding percentage is holding steady at .987 which has them sitting 9th in professional baseball, and they have turned 26 double plays.

Sproat has taken the ball for 46 innings and has tallied 42 punch outs in his pro baseball career. Sproat (0-4 career mark) is the owner of a FIP of 5.92 and he has faced 199 hitters during his time in the majors. His ERA is 6.01 (31 ER's allowed) and his WHIP is 1.466. He has surrendered 46 base hits (8.9 hits per 9 innings) with 22 walks.

The St. Louis Cardinals have recorded an on-base percentage of .327 in addition to a batting average of .242 so far this season. They have struck out on 281 occasions (14th in the league) and have earned 268 hits. St. Louis has accumulated 44 HRs so far this season as well as 161 runs batted in. The Cardinals have a team slugging percentage of .408 and they tally 5.00 runs per game (9th in the league). They have recorded 51 doubles, while walking 121 times as well as putting up 165 runs.

The Cardinals are sitting with a team WHIP of 1.416 and have a FIP of 4.64 as a pitching staff for the season. They currently have a strikeout to walk ratio of 7.00 (231 strikeouts against 126 bases on balls). They come in at 24th in the league as a staff in total hits relinquished with 296. They have allowed 37 home runs and they surrender 4.89 runs per 9 innings (22nd in the league). The St. Louis pitching staff have surrendered 162 runs on the season while holding a team ERA of 4.59 (152 earned runs surrendered).

With 48 save situations, the Cardinals have accumulated 28 holds and also 6 blown saves. St. Louis has called on relievers to step onto the hill in 18 save opportunities and they have earned 12 saves. St. Louis bullpen pitchers have an inherited score percentage of 39.3% out of their 56 inherited base runners. Their bullpen pitchers have taken the field 44 times in high leverage situations in addition to 37 occasions with runners on. They sit at 11th in baseball with a save percentage of 66.7%, and they have sent 122 bullpen pitchers onto the field for the season.

In 2,682 innings played, the Cardinals hold a efficiency on defense of 69.5% (17th in pro baseball). The St. Louis Cardinals have turned 31 double plays and have a fielding percentage of .986 (14th in MLB). The Cardinals have racked up 333 assists, 17 errors and have notched a total of 894 putouts this season.

Leahy (8-7 career win-loss mark) holds a 3.98 ERA and has surrendered 8.7 hits per nine innings. His strikeout to walk ratio is 2.54 and he has gone up against 703 opposing hitters during his career. He has surrendered a total of 74 earned runs while earning a WHIP of 1.292 and being the owner of a FIP of 3.9. So far in his pro baseball career, Leahy has allowed 162 hits while tallying 137 strikeouts in 167 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Milwaukee (-182)

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