Minnesota Twins vs Chicago White Sox Prediction, 9/5/2026 MLB Picks, Best Bets & Odds

Game: Minnesota Twins vs Chicago White Sox

Date: Saturday, September 5, 2026

Location: Rate Field in Chicago, IL

TV: Chicago Sports Network

Odds/Point Spread: Minnesota (+110) Chicago (-130)

The Minnesota Twins (67-73) are on their way to Rate Field on Saturday where they will attempt to beat the Chicago White Sox (73-67). The moneyline on this contest has the Twins at +110 and the White Sox are sitting at -130. The total is set at 8.5. The pitchers expected to start will be Taj Bradley and Anthony Kay.

Minnesota is slugging .409 and have been called out on strikes 1,114 times, while taking a walk on 454 occasions. They have compiled 628 RBI's in addition to 1,165 hits on the campaign, while their average at the plate is .246. The Twins have earned 231 doubles as a squad and have smacked 165 baseballs out of the park. They have 658 runs scored while holding a team OBP of .320. As a squad, the Minnesota Twins are compiling 4.7 runs/g, which ranks them 7th in the league.

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The Twins have compiled a team earned run average of 4.63 over the course of the season (25th in baseball), and they have struck out 1,164 hitters. Twins pitchers have conceded 158 long balls in addition to 696 runs (27th in the league). They have walked 506 opposing players and their FIP sits at 4.25 as a team for the year. Minnesota has yielded 1,196 base hits (8.7 per 9 innings) and 636 earned runs. Their strikeout to walk ratio sits at 2.30 and the pitching staff has earned a collective WHIP of 1.38.

The Twins bullpen have accumulated a save rate of 70.4% and stepped onto the hill in 145 save situations. They have earned 38 saves for the year and have missed out on 16 of 54 save opportunities. The bullpen pitchers have inherited 195 runners this season and 35.9% of them crossing home plate. Twins pitchers have stepped onto the hill with runners on 136 times as well as having 145 appearances in high leverage situations. The Twins have dispatched 461 relief pitchers to the mound over the course of the season. The relief pitchers have tallied 87 holds on the campaign (7th in baseball).

The Minnesota Twins are sitting with 3,710 putouts at this point in the season, in addition to 1,078 assists and 65 errors. Their fielding percentage is currently at .987 which has them ranked 12th in MLB, and have accumulated 97 double plays. The Twins have turned 69.1% of baseballs in play into outs in their 11,130 innings on the diamond, which has them ranked 24th in MLB.

Bradley has taken the ball for 539 innings and has accounted for 588 strikeouts in his pro baseball career. His earned run average is 4.57 (274 ER's allowed) and his WHIP is 1.291. He has allowed 488 hits (8.1 hits per 9 innings) and has 208 free passes. Bradley (29-33 win-loss mark in his career) holds a FIP of 4.50 while he has faced 2,297 batters during his time in the major leagues.

Chicago has accounted for 181 HRs so far this year to go along with 631 RBIs. They have 220 doubles, while walking 503 times and scoring 662 runs. The Chicago White Sox have tallied an OBP of .319 and a batting average of .236 for the season. The White Sox hold a team slugging percentage of .405 and they earn 4.73 runs per game (6th in baseball). They have been called out on strikes on 1,272 occasions (6th in the league) and have earned a total of 1,112 base hits.

The Chicago pitching staff have relinquished 623 runs so far this year while holding an ERA of 4.14 (574 earned runs conceded). They have given up 158 long balls and they relinquish 4.50 runs per 9 innings (14th in the league). The White Sox are sitting with a team WHIP of 1.310 and have a FIP of 4.29 as a team so far this year. Their K/BB ratio comes in at 8.40 (1,167 strikeouts against 508 bases on balls). They sit at 13th in baseball as a pitching staff in total hits relinquished with 1,126.

They are ranked 20th in the league with a save percentage of 58.7%, and they have dispatched 465 relievers to the hill so far this season. Their relief pitchers have taken the field 142 times in high leverage situations and also on 155 occasions with base runners. Sitting with 121 save situations, the White Sox have accrued 55 holds and also 26 blown saves. Chicago has called on relievers to step onto the mound in 63 save opportunities and they have tallied 37 saves. Chicago relievers hold an inherited score percentage of 30.0% out of their 227 inherited base runners.

In 11,223 innings on the field, the White Sox hold a defensive efficiency of 70.5% (12th in pro baseball). The Chicago White Sox have turned 92 double plays and have a fielding percentage of .986 (15th in professional baseball). The White Sox have racked up 1,136 assists, 71 errors and have earned a total of 3,741 putouts so far this year.

Kay (13-9 mark in his career) is the owner of a 4.80 ERA while giving up 9.2 hits per 9 innings. His K/BB ratio is 2.09 and he has faced 1,004 hitters in his pro baseball career. He has given up 118 ER's while earning a WHIP of 1.455 and being the owner of a FIP of 4.7. So far in his career, Kay has allowed 226 hits while totaling 201 K's in 221 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Chicago (-130)

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