Minnesota Twins vs Cleveland Guardians Prediction, 5/10/2026 MLB Picks, Best Bets & Odds

Game: Minnesota Twins vs Cleveland Guardians

Date: Sunday, May 10, 2026

Location: Progressive Field in Cleveland, OH

TV: MLB.TV

Odds/Point Spread: Minnesota (+102) Cleveland (-122)

Progressive Field is the location where the Cleveland Guardians (20-19) will take on the Minnesota Twins (16-22) on Sunday. The line on this contest has the Twins at +102 while the Guardians are coming in at -122. The over/under is 8.5. The pitchers taking the mound will be Taj Bradley and Gavin Williams.

As a unit, the Minnesota Twins are notching 4.8 runs per outing, which is 9th in baseball. They have accounted for 183 runs scored while holding a team on-base percentage of .326. The Twins have accumulated 53 doubles as a squad and have knocked 43 balls out of the stadium. They have accrued 175 runs batted in as well as 298 base knocks so far this season, while their average at the plate is .235. Minnesota is slugging .384 and have struck out 322 times, while being walked on 151 occasions.

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The Twins hold a team ERA of 4.80 for the season (27th in baseball), and the staff has rung up 288 batters. Twins pitchers have surrendered 38 home runs in addition to 195 runs in total (27th in MLB). Their pitching staff has walked 136 opposing players and their FIP sits at 4.34 as a unit for the year. Minnesota has given up 324 hits (8.8 per 9 innings) and 177 earned runs. They have accumulated a K/BB ratio of 2.12 and the pitching staff has a collective WHIP of 1.39.

The Twins have dispatched 125 relief pitchers to the hill on the campaign. The bullpen pitchers have inherited 59 base runners this year and 40.7% of those players crossing home plate. The relievers have earned 24 holds for the year (12th in the league). Twins pitchers have entered the contest with opponents on base 41 times in addition to having 32 appearances in high leverage situations. They have compiled 6 saves so far this year and have not converted 5 of their 11 save chances. The Twins relievers have earned a save rate of 54.5% and have entered the game in 35 save situations.

The Minnesota Twins have 996 putouts at this point in the season, as well as 292 assists and 18 errors. Their fielding rate is at .986 which puts them in 17th in professional baseball, and have a total of 31 double plays. The Twins have turned 69.1% of balls in play into outs in their 2,988 innings on the diamond, which ranks them 23rd in the majors.

Bradley has pitched in 432 innings and has totaled 462 strikeouts so far in his MLB career. His ERA is 4.64 (223 earned runs allowed) and his WHIP is 1.289. He has given up 398 base hits (8.3 hits per 9 innings) and has 159 walks. Bradley (23-28 win-loss mark in his career) is the owner of a FIP of 4.58 and he has faced 1,842 opposing hitters in the major leagues.

Cleveland has accounted for 39 home runs on the year to go along with 155 runs batted in. They have recorded 67 two-baggers, while walking 156 times and earning 162 runs. The Cleveland Guardians have earned an on-base percentage of .319 and a team batting average of .231 so far this year. The Guardians hold a team slugging % of .377 and they score 4.15 runs per outing (21st in the league). They have struck out on 297 occasions (22nd in baseball) and have a total of 296 hits.

The Guardians are sitting with a team WHIP of 1.284 and have a FIP of 4.25 as a pitching staff over the course of the season. They currently have a K/BB ratio of 9.20 (349 strikeouts against 135 bases on balls). They rank 16th in baseball as a staff in total hits allowed with 303. They have allowed 49 homers and they surrender 4.38 runs per 9 innings (13th in the league). The Cleveland pitching staff have allowed 166 runs on the campaign while holding a team ERA of 4.01 (152 earned runs yielded).

They sit at 4th in MLB with a save rate of 75.0%, and they have dispatched 126 relievers to the hill for the season. Their relievers have stepped onto the mound 43 times in high leverage situations and also on 38 occasions with runners on base. Sitting with 46 save situations, the Guardians have earned 29 holds and 4 blown saves. Cleveland has called on bullpen pitchers to step onto the mound in 16 save chances and they have walked away with 12 saves. Cleveland bullpen pitchers have an inherited score percentage of 29.7% out of their 64 inherited runners.

In 3,072 innings on the diamond, the Guardians have accumulated a efficiency on defense of 70.6% (12th in professional baseball). The Cleveland Guardians have turned 27 double plays and have a fielding percentage of .987 (10th in the majors). The Guardians have racked up 297 assists, 17 errors and have amassed 1,024 putouts over the course of the season.

In his MLB career, Williams has surrendered 301 base knocks while he has tallied 393 K's in 374 frames. Williams (23-22 career mark) has earned a 3.51 earned run average and has conceded 7.2 hits per nine innings. He has conceded 146 earned runs while earning a WHIP of 1.266 and being the owner of a FIP of 3.5. He has a K/BB ratio of 2.27 and he has faced 1,579 batters in his career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Minnesota (+102)

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