Minnesota Twins vs Los Angeles Angels Prediction, 9/18/2026 MLB Picks, Best Bets & Odds

Game: Minnesota Twins vs Los Angeles Angels

Date: Friday, September 18, 2026

Location: Angel Stadium in Anaheim, CA

TV: FanDuel Sports Network West

Odds/Point Spread: Minnesota (-132) Los Angeles (+110)

The Los Angeles Angels (58-94) welcome the Minnesota Twins (71-81) at Angel Stadium on Friday. The line on this contest has the Twins at -132 and the Angels are sitting at +110. The total is set at 9. The expected starting pitchers will be Connor Prielipp and Grayson Rodriguez.

As a squad, the Minnesota Twins are notching 4.6 runs per game, which has them sitting at 11th in baseball. They have a total of 692 runs scored while holding a team on-base percentage of .317. The Twins have accrued 245 two-baggers as a unit and have smacked 176 baseballs out of the park. They have accrued 662 runs batted in in addition to 1,246 base knocks so far this season, while their average at the plate comes in at .243. Minnesota is slugging .403 and have struck out 1,212 times, while drawing a walk on 486 occasions.

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Their K/BB ratio is 2.31 and the pitching staff has a collective WHIP of 1.38. Twins pitchers have allowed 178 home runs and also 765 runs in total (26th in the league). Minnesota has given up 1,298 base knocks (8.7 per 9 innings) and 698 earned runs. The Twins hold a team ERA of 4.67 on the season (26th in the league), and they have struck out 1,278 batters. They have walked 553 opposing hitters and their FIP sits at 4.30 as a squad so far this year.

Twins pitchers have come into the game with players on base 151 times in addition to having 163 appearances in high leverage situations. The relief pitchers have recorded 99 holds for the season (4th in the league). The Twins bullpen have compiled a save rate of 68.3% and have entered the game in 163 save situations. They have accumulated 41 saves so far this year and have blown 19 out of their 60 save opportunities. The relievers have inherited 217 runners over the course of the season with 37.3% of them ended up scoring. The Twins have dispatched 506 relief pitchers to the mound for the season.

The Twins have turned 69.2% of baseballs in play into outs out of their 12,102 innings, which ranks them 22nd in baseball. The Minnesota Twins have earned a total of 4,034 putouts for the season, in addition to 1,156 assists and 69 errors. Their fielding rate sits at .987 which has them sitting 11th in baseball, and they have turned 103 double plays.

Prielipp has taken the hill for 113 innings and has 117 strikeouts during his career. Prielipp (5-7 career win-loss mark) is the owner of a FIP of 5.17 while going up against 488 opposing hitters in the majors. His ERA is 5.25 (66 ER's allowed) and his WHIP is 1.344. He has conceded 112 hits (8.9 hits per 9 innings) and has had 40 walks.

The Los Angeles Angels have accounted for an on-base percentage of .309 and a team batting average of .234 for the year. They have struck out on 1,444 occasions (2nd in MLB) and have earned a total of 1,186 base hits. Los Angeles has tallied 146 long balls this season to go along with 587 RBIs. The Angels have a SLG% of .371 and they are scoring 4.04 runs per game (30th in the league). They have recorded 229 doubles, while getting a free base 470 times and scoring 614 runs.

The Angels have a WHIP of 1.341 and have a FIP of 4.09 as a staff on the campaign. They are currently ranked 7th in the league as a pitching staff in total hits given up with 1,190. The Los Angeles pitching staff have yielded 692 runs for the year and come in with a team ERA of 4.21 (627 earned runs given up). They have earned a strikeout to walk ratio of 9.10 (1,357 strikeouts vs 608 free passes). They have given up 154 home runs and they surrender 4.64 runs per 9 innings (19th in the league).

With 142 save situations, the Angels have 87 holds in addition to 28 blown saves. Los Angeles has had relievers take the mound in 52 save opportunities and they have come away with 24 saves. Los Angeles bullpen pitchers have an inherited score percentage of 38.5% out of their 226 inherited base runners. Their bullpen pitchers have taken the field 160 times in high leverage situations and also on 149 occasions with runners on. They rank 30th in baseball with a save rate of 46.2%, and they have dispatched 485 relievers onto the field on the year.

The Los Angeles Angels have gotten 104 double plays and own a fielding percentage of .984 (19th in baseball). The Angels have accrued 1,274 assists, 84 errors and have accumulated 4,024 putouts during this campaign. In their 12,072 innings on the diamond, the Angels have earned a defensive efficiency of 69.7% (16th in professional baseball).

So far in his MLB career, Rodriguez has conceded 328 base hits while he has tallied 338 punch outs in 325 innings. Rodriguez (24-15 record in his career) has earned a 4.65 ERA while giving up 9.1 hits per 9 innings. He has conceded 168 ER's while holding a WHIP of 1.365 and being the owner of a FIP of 4.6. He has a strikeout to walk ratio of 2.91 and he has faced 1,399 opposing batters so far in his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Los Angeles (+110)

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