New York Mets vs Chicago White Sox Prediction, 8/21/2026 MLB Picks, Best Bets & Odds

Game: New York Mets vs Chicago White Sox

Date: Friday, August 21, 2026

Location: Rate Field in Chicago, IL

TV: Chicago Sports Network

Odds/Point Spread: New York (-144) Chicago (+120)

The New York Mets (58-70) are on their way to Rate Field on Friday where they will try to defeat the Chicago White Sox (66-60). The moneyline on this contest has New York at -144 and Chicago is opening at +120. The total is set at 8.5. The starting pitchers are Sean Manaea and Sean Burke.

As a team, the New York Mets are compiling 4.2 runs per contest, which ranks them 23rd in the league. They have accumulated 531 runs scored while holding a team OBP of .307. The Mets have earned 159 doubles as a squad and have knocked 155 balls out of the park. They have amassed 508 RBI's in addition to 1,009 hits for the season, and their batting average is .235. New York has a slugging rate of .388 and have been rung up 1,087 times, while being walked on 414 occasions.

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The Mets have compiled a team ERA of 4.06 for the year (14th in baseball), and their staff has struck out 1,153 batters. Mets pitchers have yielded 138 home runs and also 573 total runs (18th in MLB). Their pitching staff has walked 455 opposing hitters and their FIP sits at 4.00 as a unit on the season. New York has relinquished 1,025 base knocks (8.1 per 9 innings) as well as 514 earned runs. They have a strikeout to walk ratio of 2.53 and their pitching staff has earned a collective WHIP of 1.30.

The Mets relief pitchers have accumulated a save percentage of 64.1% and have stepped onto the mound in 95 save situations. They have recorded 25 saves so far this season and have not converted 14 of their 39 save opportunities. The relief pitchers have inherited 166 base runners on the campaign with 28.3% of those players crossing the plate. Mets bullpen pitchers have come into the game with runners on 120 times as well as having 133 appearances in high leverage situations. The Mets have sent 391 relief pitchers to the mound for the season. The relievers have a total of 54 holds for the season (26th in MLB).

The Mets have turned 69.4% of balls in play into outs in their 10,257 innings on the field, which has them sitting at 21st in MLB. The New York Mets have notched a total of 3,419 putouts this season, as well as 1,009 assists and 82 errors. Their fielding percentage sits at .982 which ranks 27th in baseball, and they have turned 80 double plays.

Manaea has taken the mound for 1,356 innings and has accounted for 1,297 punch outs so far in his pro baseball career. Manaea (83-71 career win-loss mark) is the owner of a FIP of 4.03 while he has gone up against 5,677 opposing hitters in the major leagues. His earned run average is 4.10 (617 earned runs allowed) and his career WHIP is 1.212. He has allowed 1,259 hits (8.4 hits per nine innings) and has had 384 walks.

The Chicago White Sox have tallied a team on-base percentage of .319 and a team batting average of .239 this year. They have struck out on 1,147 occasions (6th in the league) and have recorded 1,016 hits. Chicago is sitting with 167 home runs for the season to go along with 578 RBIs. The White Sox have a team SLG% of .411 and they tally 4.80 runs per contest (7th in the league). They have recorded 203 doubles, while taking a walk 437 times and putting up 605 runs.

The White Sox are sitting with a team WHIP of 1.297 and are the owners of a FIP of 4.22 as a pitching staff for the year. They are currently ranked 9th in MLB as a pitching staff in total hits given up with 1,002. The Chicago pitching staff have conceded 558 runs so far this year while holding a team ERA of 4.08 (510 earned runs given up). They currently have a strikeout to walk ratio of 8.50 (1,063 strikeouts against 457 walks). They have relinquished 140 home runs and they surrender 4.46 runs per 9 innings (16th in the league).

Chicago relief pitchers have an inherited score percentage of 31.5% out of 200 inherited runners. Their bullpen pitchers have taken the field 130 times in high leverage situations and on 140 occasions with base runners. Sitting with 112 save situations, the White Sox have tallied 53 holds and 25 blown saves. They rank 24th in the league with a save percentage of 56.9%, and they have dispatched 426 bullpen pitchers to the hill for the season.

Out of their 10,125 innings on the field, the White Sox hold a defensive efficiency of 70.6% (11th in the majors). The Chicago White Sox have gotten 87 double plays and hold a fielding percentage of .985 (18th in the majors). The White Sox have 1,035 assists, 68 errors and are sitting with 3,375 putouts so far this season.

In his career, Burke has surrendered 256 base knocks while totaling 309 K's in 293 frames. Burke (13-17 career mark) is the owner of a 3.53 earned run average while surrendering 7.9 hits per 9 innings. He has conceded a total of 115 ER's while holding a WHIP of 1.256 and having a FIP of 3.5. His strikeout to walk ratio is 2.76 and he has faced 1,243 batters so far in his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take New York (-144)

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