New York Yankees vs Arizona Diamondbacks Prediction, 9/18/2026 MLB Picks, Best Bets & Odds

Game: New York Yankees vs Arizona Diamondbacks

Date: Friday, September 18, 2026

Location: Chase Field in Phoenix, AZ

TV: DBACKS.TV

Odds/Point Spread: New York (-128) Arizona (+106)

Chase Field is the location where the Arizona Diamondbacks (80-73) will compete against the New York Yankees (88-64) on Friday. The odds on this game have New York at -128 while Arizona is sitting at +106. The over/under comes in at 9. The pitchers taking the mound will be Gerrit Cole and Eduardo Rodriguez.

New York has a slugging % of .409 and have been called out on strikes 1,394 times, while drawing a walk on 543 occasions. They have recorded 666 runs batted in in addition to 1,185 hits on the campaign, while their team batting average is sitting at .235. The Yankees have tallied 216 two-baggers as a team and have smacked 209 balls out of the park. They have earned 697 runs scored while having a team on-base percentage of .312. As a squad, the New York Yankees are notching 4.6 runs per contest, which puts them at 9th in the league.

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The Yankees have an ERA of 3.19 so far this season (1st in the league), and their staff has struck out 1,363 hitters. Yankees pitchers have yielded 156 home runs and also 561 runs in total (1st in baseball). Their pitching staff has walked 457 opposing players and their FIP sits at 3.71 as a squad on the campaign. New York has given up 1,126 base knocks (7.4 per 9 innings) and 483 earned runs. Their strikeout to walk ratio is 2.98 and the pitching staff holds a WHIP of 1.16.

The Yankees have dispatched 502 relievers to the hill on the season. The relief pitchers have inherited 257 runners for the year with 20.6% of them crossing home plate. The relief pitchers have racked up 86 holds so far this season (12th in the league). Yankees bullpen pitchers have entered the contest with runners on 181 times and also have had 170 appearances in high leverage situations. They have compiled 44 saves on the year and have not converted 28 of 72 save chances. The Yankees bullpen have recorded a save percentage of 61.1% and have stepped onto the mound in 161 save situations.

The Yankees have transformed 71.4% of balls hit into play into outs out of their 12,258 innings, which has them sitting 4th in the majors. The New York Yankees have amassed 4,086 putouts on the campaign, as well as 1,321 assists and 90 errors. Their fielding rate is at .984 which is 22nd in MLB, and they have turned 117 double plays.

Cole has taken the mound for 2,069 innings and has accounted for 2,368 punch outs in his MLB career. Cole (161-89 win-loss mark in his career) has earned a FIP of 3.16 and he has gone up against 8,336 opposing hitters in the major leagues. His ERA is 3.21 (737 ER's allowed) and he has a WHIP of 1.091. He has conceded 1,735 base hits (7.5 hits per 9 innings) and has had 522 walks.

The Arizona Diamondbacks have recorded an OBP of .316 and a batting average of .244 this year. They have been rung up on 1,128 occasions (28th in MLB) and have 1,251 hits. Arizona has recorded 154 long balls for the year to go along with 647 runs batted in. The Diamondbacks hold a slugging percentage of .397 and they average 4.43 runs per outing (18th in baseball). They have hit 256 doubles, while getting a free base 510 times and earning 678 runs.

The Diamondbacks hold a team WHIP of 1.277 in addition to having a FIP of 4.30 as a unit for the year. They sit at 21st in MLB as a pitching staff in total hits surrendered with 1,285. The Arizona pitching staff have allowed 678 runs over the course of the season while holding an ERA of 4.09 (619 earned runs yielded). Their K/BB ratio sits at 7.10 (1,073 strikeouts vs 456 walks). They have conceded 171 HR's and they surrender 4.48 runs per 9 innings (13th in MLB).

Arizona relievers have an inherited score rate of 26.8% out of 198 inherited runners. Their bullpen pitchers have stepped onto the hill 165 times in high leverage situations and also on 138 occasions with base runners. With 134 save situations, the Diamondbacks have accrued 79 holds and 17 blown saves. They rank 10th in MLB with a save rate of 68.5%, and they have sent 516 relievers onto the field this season.

In their 12,267 innings played, the Diamondbacks have accumulated a defensive efficiency of 71.2% (7th in pro baseball). The Arizona Diamondbacks have gotten 131 double plays and own a fielding percentage of .989 (2nd in baseball). The Diamondbacks have racked up 1,319 assists, 60 errors and are sitting with 4,089 putouts on the season.

Thus far in his career, Rodriguez has allowed 1,439 base hits and he has 1,432 strikeouts in 1,482 innings. He has given up a total of 659 ER's while earning a WHIP of 1.317 and having a FIP of 3.9. His K/BB ratio is 2.79 and he has gone up against 6,315 batters during his pro baseball career. Rodriguez (109-72 career record) has a 4.00 ERA while giving up 8.7 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Arizona (+106)

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