New York Yankees vs Arizona Diamondbacks Prediction, 9/20/2026 MLB Picks, Best Bets & Odds

Game: New York Yankees vs Arizona Diamondbacks

Date: Sunday, September 20, 2026

Location: Chase Field in Phoenix, AZ

TV: DBACKS.TV

Odds/Point Spread: New York (-132) Arizona (+110)

Chase Field is the location where the Arizona Diamondbacks (80-73) will try to beat the New York Yankees (88-64) on Sunday. The line on this matchup has the Yankees at -132 and the Diamondbacks are priced at +110. The total is 8.5. The expected starting pitchers are Will Warren and Corbin Burnes.

New York has a slugging percentage of .409 and have struck out 1,394 times, while taking a walk on 543 occasions. They have accounted for 666 RBI's and 1,185 hits this season, and their team batting average is .235. The Yankees have tallied 216 two-baggers as a unit and have hit 209 balls out of the park. They have notched a total of 697 runs scored and have an on-base percentage of .312. As a squad, the New York Yankees are putting up 4.6 runs per contest, which puts them at 9th in the league.

Get all of our MLB Expert Picks

Their strikeout to walk ratio sits at 2.98 and the pitching staff has a team WHIP of 1.16. Yankees pitchers have relinquished 156 home runs and 561 runs in total (1st in the league). New York has given up 1,126 base knocks (7.4 per 9 innings) as well as 483 earned runs. The Yankees have compiled a team ERA of 3.19 for the season (1st in the league), and they have rung up 1,363 hitters. They have walked 457 opposing hitters and their FIP is 3.71 as a team for the season.

The Yankees bullpen have recorded a save rate of 61.1% and have entered the game in 161 save situations. They have tallied 44 saves so far this year and have blown 28 of 72 save chances. The relievers have inherited 257 runners for the year with 20.6% of them crossing home plate. Yankees relief pitchers have stepped onto the hill with players on base 181 times and also have had 170 appearances in high leverage situations. The Yankees have sent 502 relief pitchers to the hill so far this year. The relievers have a total of 86 holds this year (12th in baseball).

The New York Yankees have earned a total of 4,086 putouts at this point in the season, in addition to 1,321 assists and 90 errors. Their fielding rate is holding at .984 which puts them in 21st in the majors, and they have turned 117 double plays. The Yankees have turned 71.4% of balls hit into play into outs out of their 12,258 innings on the field, which has them ranked 5th in baseball.

Warren has taken the hill for 333 innings and has accounted for 347 punch outs during his pro baseball career. His earned run average is 4.59 (170 ER's allowed) and his WHIP is 1.402. He has given up 341 hits (9.2 hits per nine innings) and has had 126 walks. Warren (19-17 career record) sits with a FIP of 4.53 while he has gone up against 1,462 opposing hitters in the majors.

The Arizona Diamondbacks have accounted for an OBP of .316 and a batting average of .244 on the year. They have been called out on strikes on 1,128 instances (28th in the league) and have tallied 1,251 base hits. Arizona has compiled 154 home runs on the season to go along with 647 RBIs. The Diamondbacks hold a team SLG% of .397 and they are scoring 4.43 runs per game (18th in the league). They have put up 256 two-baggers, while taking a walk 510 times as well as putting up 678 runs.

The Arizona pitching staff have conceded 678 runs for the year while having an ERA of 4.09 (619 earned runs allowed). They have given up 171 home runs and they concede 4.48 runs per 9 innings (13th in baseball). The Diamondbacks are sitting with a team WHIP of 1.277 and are the owners of a FIP of 4.29 as a staff on the season. Their K/BB ratio is 7.10 (1,073 strikeouts against 456 free passes). They come in at 21st in the league as a pitching staff in total hits given up with 1,285.

Sitting with 134 save situations, the Diamondbacks have accumulated 79 holds in addition to 17 blown saves. Arizona has had bullpen pitchers enter the game in 54 save opportunities and they have earned 37 saves. Arizona bullpen pitchers have an inherited score percentage of 26.8% of 198 inherited base runners. Their relievers have taken the field 165 times in high leverage situations in addition to 138 occasions with runners on. They rank 10th in MLB with a save rate of 68.5%, and they have sent 516 relief pitchers onto the diamond so far this year.

The Arizona Diamondbacks have turned 131 double plays and have a fielding percentage of .989 (2nd in professional baseball). The Diamondbacks have accrued 1,319 assists, 60 errors and have 4,089 putouts so far this year. In their 12,267 innings played, the Diamondbacks have earned a defensive efficiency of 71.2% (7th in MLB).

During his career, Burnes has given up 763 hits while he has totaled 1,120 punch outs in 975 innings pitched. Burnes (63-38 career mark) is the owner of a 3.17 earned run average while conceding 7.0 hits per nine innings. He has given up 344 earned runs while earning a WHIP of 1.072 and a FIP of 3.1. He has a strikeout to walk ratio of 3.97 and he has gone up against 3,946 opposing hitters in his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Arizona (+110)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here

Get MLB picks on every single game, or if you want our very best bets by the experts, sign up for your free $60 account with a guarantee.