New York Yankees vs San Diego Padres Prediction, 9/6/2026 MLB Picks, Best Bets & Odds

Game: New York Yankees vs San Diego Padres

Date: Sunday, September 6, 2026

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: New York (-122) San Diego (+102)

The San Diego Padres (73-67) will compete against the New York Yankees (80-60) at Petco Park on Sunday. The moneyline on this contest has the Yankees at -122 while the Padres open at +102. The over/under comes in at 8. The starting pitchers will be Gerrit Cole and Michael King.

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The Yankees have accrued 201 doubles as a unit and have smacked 192 balls out of the stadium. New York has a slugging percentage of .409 and have been rung up 1,288 times, while being walked on 502 occasions. As a squad, the New York Yankees are notching 4.5 runs per game, which has them sitting at 11th in baseball. They have accumulated 607 RBI's as well as 1,083 base knocks over the course of the season, while their team batting average is .234. They are sitting with 636 runs scored and have an OBP of .311.

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They have a strikeout to walk ratio of 2.98 and their pitching staff has earned a collective WHIP of 1.17. Yankees pitchers have conceded 137 long balls and 521 runs in total (1st in baseball). New York has relinquished 1,047 base hits (7.5 per 9 innings) as well as 451 earned runs. The Yankees have compiled a team earned run average of 3.24 this year (1st in MLB), and they have struck out 1,256 batters. They have walked 421 opposing hitters and their FIP comes in at 3.65 as a squad this year.

The Yankees relief pitchers have earned a save rate of 60.6% and have come into the game in 147 save situations. They have compiled 40 saves on the year and have blown 26 of 66 chances to get a save. The bullpen pitchers have inherited 237 runners for the season and 20.3% of them earned a run for their team. Yankees relief pitchers have stepped onto the hill with runners on base 166 times and also have had 161 appearances in high leverage situations. The Yankees have dispatched 465 relief pitchers to the mound so far this season. The relievers have racked up 79 holds on the campaign (11th in baseball).

The New York Yankees have amassed 3,755 putouts for the season, as well as 1,220 assists and 81 errors. Their fielding percentage is holding steady at .984 which is 21st in baseball, and they have turned 108 double plays. The Yankees have converted 71.0% of baseballs in play into outs out of 11,265 innings on the field, which has them ranked 8th in pro baseball.

Cole has pitched in 2,058 innings and has racked up 2,361 punch outs in his pro baseball career. Cole (161-87 career win-loss mark) sits with a FIP of 3.14 while facing 8,287 hitters in the major leagues. His earned run average is 3.18 (728 earned runs allowed) and he has a career WHIP of 1.089. He has surrendered 1,720 base knocks (7.5 hits per 9 innings) with 522 free passes.

The San Diego Padres have compiled an OBP of .315 and a team batting average of .237 over the course of the season. They have been called out on strikes on 1,139 occasions (20th in MLB) and have earned 1,096 base hits. San Diego has accounted for 153 HRs this year to go along with 572 RBIs. The Padres hold a team SLG% of .387 and they have an average of 4.24 runs per outing (22nd in baseball). They have notched 202 two-baggers, while walking 485 times as well as scoring 594 runs.

The Padres hold a team WHIP of 1.292 with a FIP of 4.19 as a unit this year. They sit at 12th in the league as a pitching staff in total hits allowed with 1,125. The San Diego pitching staff have given up 584 runs this season while having an ERA of 3.94 (542 earned runs allowed). They currently have a K/BB ratio of 8.20 (1,131 strikeouts against 475 bases on balls). They have surrendered 155 homers and they allow 4.25 runs per 9 innings (9th in MLB).

San Diego relief pitchers hold an inherited score rate of 31.8% out of 220 inherited runners. Their bullpen pitchers have come in 156 times in high leverage situations in addition to 136 occasions with runners on base. With 146 save situations, the Padres have earned 85 holds and 18 blown saves. They rank 11th in baseball with a save percentage of 69.0%, and they have dispatched 470 relief pitchers onto the diamond so far this season.

The San Diego Padres have gotten 112 double plays and have earned a fielding percentage of .988 (5th in professional baseball). The Padres have racked up 1,236 assists, 59 errors and have amassed 3,715 putouts on the campaign. In their 11,145 innings on the field, the Padres have a defensive efficiency of 70.6% (10th in the majors).

In his career, King has conceded 544 base knocks while he has accumulated 700 strikeouts in 656 innings. King (40-38 career win-loss mark) is the owner of a 3.21 ERA while conceding 7.5 hits per nine innings. He has surrendered a total of 234 ER's while earning a WHIP of 1.187 and having a FIP of 3.2. His strikeout to walk ratio is 2.98 and he has faced 2,731 hitters so far in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take New York (-122)

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