Pittsburgh Pirates vs Chicago Cubs Prediction, 9/13/2026 MLB Picks, Best Bets & Odds

Game: Pittsburgh Pirates vs Chicago Cubs

Date: Sunday, September 13, 2026

Location: Wrigley Field in Chicago, IL

TV: Marquee

Odds/Point Spread: Pittsburgh (+125) Chicago (-145)

The Pittsburgh Pirates (74-73) are on their way to Wrigley Field on Sunday where they will try to beat the Chicago Cubs (81-66). The odds on this game have the Pirates at +125 while the Cubs are priced at -145. The over/under is set at 8. The starting pitchers are Bubba Chandler and Matthew Boyd.

Pittsburgh has a slugging percentage of .403 and have been called out on strikes 1,376 times, while taking a walk on 520 occasions. They have recorded 676 runs batted in in addition to 1,280 hits on the year, while their average at the plate is at .253. The Pirates have tallied 222 two-baggers as a team and have hit 168 baseballs out of the park. They have earned 709 runs scored while holding a team on-base percentage of .331. As a team, the Pittsburgh Pirates are recording 4.8 runs per outing, which has them sitting at 5th in the league.

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They have a K/BB ratio of 2.55 and their pitching staff has recorded a WHIP of 1.30. Pirates pitchers have allowed 141 home runs in addition to 673 total runs (20th in the league). Pittsburgh has surrendered 1,169 base hits (8.0 per 9 innings) and 602 earned runs. The Pirates are sitting with a team earned run average of 4.13 for the season (15th in baseball), and they have struck out 1,357 batters. Their pitching staff has walked 532 opposing hitters and their FIP is 3.82 as a team this year.

The Pirates relievers have accumulated a save percentage of 60.0% and stepped onto the hill in 126 save situations. They have earned 33 saves over the course of the season and have blown 22 of 55 chances to get a save. The relief pitchers have inherited 180 runners this year with 31.7% of those players crossing home plate. Pirates relief pitchers have gone to the mound with runners on base 123 times as well as having 140 appearances in high leverage situations. The Pirates have sent 479 relief pitchers to the mound on the campaign. The relief pitchers have racked up 69 holds so far this year (25th in baseball).

The Pittsburgh Pirates have accumulated 3,940 putouts on the year, as well as 1,161 assists and 91 errors. Their fielding percentage is holding steady at .982 which has them sitting 26th in pro baseball, and they have turned 119 double plays. The Pirates have converted 69.0% of baseballs in play into outs in their 11,820 innings on the diamond, which has them ranked 26th in MLB.

Chandler has taken the hill for 173 innings and is sitting with 160 K's during his pro baseball career. Chandler (11-10 mark in his career) holds a FIP of 4.15 and he has faced 737 opposing batters in the major leagues. His earned run average is 4.21 (81 ER's allowed) and he has a career WHIP of 1.265. He has conceded 144 hits (7.5 hits per 9 innings) and has 75 walks.

The Chicago Cubs are sitting with an on-base percentage of .339 as well as a team batting average of .251 this year. They have been rung up on 1,243 occasions (12th in MLB) and have 1,267 base knocks. Chicago has compiled 203 home runs on the campaign as well as 736 RBIs. The Cubs hold a team SLG% of .429 and they are earning 5.31 runs per contest (1st in MLB). They have hit 248 doubles, while taking a walk 620 times and earning 780 runs.

The Cubs have a WHIP of 1.269 and are the owners of a FIP of 4.71 as a unit this season. They have earned a K/BB ratio of 7.80 (1,142 strikeouts against 449 walks). They come in at 18th in baseball as a pitching staff in total hits allowed with 1,216. They have conceded 221 homers and they surrender 4.47 runs per 9 innings (14th in baseball). The Chicago pitching staff have given up 652 runs on the campaign and come in with a team ERA of 4.22 (615 earned runs conceded).

They sit at 26th in MLB with a save percentage of 55.2%, and they have dispatched 471 relievers to the hill this season. Their relief pitchers have stepped onto the mound 142 times in high leverage situations and on 147 occasions with runners on. Sitting with 116 save situations, the Cubs have 51 holds and 26 blown saves. Chicago has had bullpen pitchers take the mound in 58 save opportunities and they have converted 32 saves. Chicago relief pitchers have an inherited score percentage of 32.7% out of 205 inherited base runners.

In their 11,808 innings on the diamond, the Cubs hold a efficiency on defense of 71.8% (3rd in baseball). The Chicago Cubs have turned 113 double plays and have accounted for a fielding rate of .990 (1st in pro baseball). The Cubs have accrued 1,387 assists, 54 errors and have amassed 3,936 putouts this season.

During his career, Boyd has allowed 1,153 base knocks while he has earned 1,131 punch outs in 1,197 innings pitched. He has surrendered 602 ER's while holding a WHIP of 1.271 and having a FIP of 4.5. He has a strikeout to walk ratio of 3.07 and he has faced 5,064 opposing hitters in his career. Boyd (68-81 win-loss mark in his career) is the owner of a 4.53 earned run average while allowing 8.7 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Chicago (-145)

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