Pittsburgh Pirates vs Chicago White Sox Prediction, 9/8/2026 MLB Picks, Best Bets & Odds

Game: Pittsburgh Pirates vs Chicago White Sox

Date: Tuesday, September 8, 2026

Location: Rate Field in Chicago, IL

TV: Chicago Sports Network

Odds/Point Spread: Pittsburgh (-128) Chicago (+106)

The Chicago White Sox (74-68) will try to defeat the Pittsburgh Pirates (70-73) at Rate Field on Tuesday. The odds on this game have the Pirates at -128 while the White Sox are at +106. The over/under is set at 8. The starting pitchers will be Bubba Chandler and Sean Burke.

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Pittsburgh has a slugging percentage of .402 and have struck out 1,358 times, while taking a walk on 512 occasions. They have accounted for 660 RBI's and 1,242 hits on the season, and their average at the plate is sitting at .252. The Pirates have accounted for 215 two-baggers as a unit and have hit 164 baseballs out of the stadium. They have a total of 693 runs scored while having a team OBP of .331. As a unit, the Pittsburgh Pirates are earning 4.9 runs per game, which puts them at 5th in baseball.

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They have accrued a K/BB ratio of 2.52 and their pitching staff has earned a collective WHIP of 1.31. Pirates pitchers have conceded 139 home runs and 668 total runs (22nd in the league). Pittsburgh has allowed 1,148 base hits (8.1 per 9 innings) in addition to 597 earned runs. The Pirates have compiled a team earned run average of 4.21 on the campaign (18th in MLB), and their staff has rung up 1,318 batters. Their pitching staff has walked 524 players from the other team and their FIP is 3.86 as a squad over the course of the season.

The Pirates have sent 464 relief pitchers to the mound this year. The relief pitchers have inherited 175 runners on the year with 32.6% of those players earned a run for their team. The relief pitchers have accumulated 61 holds on the campaign (27th in MLB). Pirates relief pitchers have gone to the mound with runners on base 121 times as well as having 131 appearances in high leverage situations. They have earned 30 saves for the season and have blown 22 out of their 52 save opportunities. The Pirates relief pitchers have a save rate of 57.7% and have entered the game in 115 save situations.

The Pirates have converted 68.8% of balls in play into outs out of their 11,496 innings, which ranks them 26th in baseball. The Pittsburgh Pirates have accounted for 3,832 putouts on the campaign, as well as 1,128 assists and 90 errors. Their fielding percentage is holding steady at .982 which has them ranked 27th in pro baseball, and have accumulated 116 double plays.

Chandler (10-10 record in his career) holds a FIP of 4.19 and he has faced 716 hitters in the majors. He has allowed 140 hits (7.5 hits per nine innings) with 75 walks. His ERA is 4.25 (79 ER's allowed) and his career WHIP is 1.287. Chandler has taken the hill for 167 innings and is sitting with 152 K's in his career.

The Chicago White Sox have tallied an on-base percentage of .318 and a batting average of .236 this season. They have struck out on 1,291 occasions (6th in the league) and have a total of 1,124 base hits. Chicago has 186 long balls on the campaign as well as 639 runs batted in. The White Sox hold a team SLG% of .405 and they are scoring 4.72 runs per game (7th in MLB). They have recorded 222 doubles, while taking a walk 507 times as well as scoring 670 runs.

The Chicago pitching staff have given up 630 runs so far this season while holding an ERA of 4.13 (581 earned runs relinquished). They have given up 160 homers and they relinquish 4.48 runs per 9 innings (14th in baseball). The White Sox are sitting with a team WHIP of 1.308 in addition to having a FIP of 4.29 as a team this year. They currently have a strikeout to walk ratio of 8.40 (1,177 strikeouts vs 513 walks). They come in at 13th in the league as a staff in total hits relinquished with 1,142.

They are ranked 20th in the league with a save percentage of 58.7%, and they have dispatched 472 relievers to the mound this season. Their relief pitchers have stepped onto the hill 142 times in high leverage situations and on 156 occasions with runners on base. Sitting with 121 save situations, the White Sox have amassed 55 holds and also 26 blown saves. Chicago has called on relief pitchers to step onto the hill in 63 save chances and they have tallied 37 saves. Chicago bullpen pitchers have an inherited score percentage of 29.8% out of 228 inherited runners.

The Chicago White Sox have turned 94 double plays and own a fielding percentage of .985 (16th in baseball). The White Sox have racked up 1,154 assists, 73 errors and have 3,795 putouts so far this season. In their 11,385 innings played, the White Sox have accumulated a defensive efficiency of 70.6% (12th in MLB).

During his career, Burke has allowed 266 hits and he has 322 strikeouts in 307 frames. He has given up 121 ER's while earning a WHIP of 1.269 and a FIP of 3.5. He has a strikeout to walk ratio of 2.60 and he has gone up against 1,307 opposing hitters in his pro baseball career. Burke (14-17 career win-loss mark) is the owner of a 3.54 earned run average and has given up 7.8 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Pittsburgh (-128)

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