Pittsburgh Pirates vs Detroit Tigers Prediction, 9/25/2026 MLB Picks, Best Bets & Odds

Game: Pittsburgh Pirates vs Detroit Tigers

Date: Friday, September 25, 2026

Location: Comerica Park in Detroit, MI

TV: Detroit SportsNet

Odds/Point Spread: Pittsburgh (+132) Detroit (-160)

Comerica Park is where the Detroit Tigers (74-84) will take on the Pittsburgh Pirates (80-77) on Friday. The odds on this game have Pittsburgh at +132 and Detroit is opening at -160. The over/under comes in at 8. The expected starting pitchers are Bubba Chandler and Jackson Jobe.

Pittsburgh is slugging .405 and have been called out on strikes 1,456 times, while drawing a walk on 554 occasions. They have 716 runs batted in as well as 1,368 hits for the year, while their team batting average is sitting at .254. The Pirates have tallied 240 two-baggers as a team and have hit 181 baseballs out of the stadium. They have racked up 750 runs and have an on-base percentage of .331. As a squad, the Pittsburgh Pirates are scoring 4.8 runs per outing, which has them at 5th in baseball.

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They have a K/BB ratio of 2.55 and their pitching staff holds a collective WHIP of 1.30. Pirates pitchers have conceded 150 home runs and 719 runs (19th in MLB). Pittsburgh has surrendered 1,253 hits (8.0 per 9 innings) in addition to 648 earned runs. The Pirates hold a team ERA of 4.16 so far this season (17th in the league), and their staff has rung up 1,443 hitters. Their pitching staff has walked 565 opposing hitters and their FIP comes in at 3.82 as a unit for the season.

The Pirates bullpen have a save percentage of 60.9% and have stepped onto the mound in 141 save situations. They have earned 39 saves this season and have blown 25 out of their 64 save opportunities. The relievers have inherited 192 base runners for the season and 32.8% of them ended up crossing the plate. Pirates bullpen pitchers have entered the contest with opponents on base 130 times in addition to having 154 appearances in high leverage situations. The Pirates have dispatched 512 relief pitchers to the mound this season. The relief pitchers have earned 75 holds for the season (24th in the league).

The Pittsburgh Pirates have a total of 4,204 putouts so far this season, as well as 1,241 assists and 95 errors. Their fielding rate is currently at .983 which has them sitting 25th in MLB, and have earned 126 double plays. The Pirates have turned 69.0% of balls in play into outs out of their 12,612 innings on the diamond, which has them sitting at 25th in baseball.

Chandler has taken the mound for 182 innings and has totaled 169 K's during his pro baseball career. His earned run average is 4.30 (87 earned runs allowed) and his WHIP is 1.301. He has conceded 157 hits (7.8 hits per 9 innings) with 80 free passes. Chandler (12-10 career record) is the owner of a FIP of 4.23 and he has faced 781 opposing batters during his time in the major leagues.

The Tigers have a team slugging percentage of .400 and they score 4.47 runs per game (14th in MLB). They have notched 253 two-baggers, while walking 568 times as well as earning 707 runs. Detroit has recorded 176 home runs this season as well as 670 runs batted in. They have been rung up on 1,372 instances (7th in MLB) and have earned a total of 1,284 hits. The Detroit Tigers have accumulated an OBP of .319 as well as a team batting average of .241 this season.

The Detroit pitching staff have conceded 634 runs so far this season while holding a team ERA of 3.64 (566 earned runs given up). They have allowed 162 HR's and they surrender 4.08 runs per 9 innings (7th in the league). The Tigers have a WHIP of 1.220 and have a FIP of 4.02 as a staff so far this season. They currently have a strikeout to walk ratio of 8.20 (1,272 strikeouts against 495 bases on balls). They are currently ranked 5th in MLB as a pitching staff in total hits given up with 1,211.

Detroit relievers hold an inherited score rate of 26.1% of 249 inherited runners. Their relief pitchers have come in 135 times in high leverage situations in addition to 168 occasions with runners on. With 136 save situations, the Tigers have compiled 71 holds and 32 blown saves. They rank 28th in the league holding a save rate of 49.2%, and they have sent 492 relief pitchers to the hill this year.

The Detroit Tigers have gotten 126 double plays and have earned a fielding percentage of .986 (12th in pro baseball). The Tigers have 1,411 assists, 77 errors and have notched a total of 4,194 putouts on the season. In their 12,582 innings on the field, the Tigers are sitting with a defensive efficiency of 71.5% (4th in professional baseball).

During his pro baseball career, Jobe has given up 82 base hits while he has totaled 84 strikeouts in 93 innings pitched. Jobe (6-4 career mark) has a 3.96 ERA while surrendering 7.9 hits per nine innings. He has given up a total of 41 earned runs while holding a WHIP of 1.330 and a FIP of 3.9. He has a strikeout to walk ratio of 2.00 and he has gone up against 406 hitters during his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Pittsburgh (+132)

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