Pittsburgh Pirates vs Milwaukee Brewers Prediction, 8/5/2026 MLB Picks, Best Bets & Odds

Game: Pittsburgh Pirates vs Milwaukee Brewers

Date: Wednesday, August 5, 2026

Location: American Family Field in Milwaukee, WI

TV: Brewers.TV

Odds/Point Spread: Pittsburgh (+125) Milwaukee (-150)

American Family Field is the site where the Milwaukee Brewers (69-43) will attempt to beat the Pittsburgh Pirates (57-57) on Wednesday. The moneyline on this contest has Pittsburgh at +125 and Milwaukee is coming in at -150. The betting total comes in at 9. The expected starting pitchers will be Paul Skenes and Kyle Harrison.

Pittsburgh has a slugging percentage of .414 and have been called out on strikes 1,076 times, while drawing a walk on 414 occasions. They have recorded 557 RBI's and 1,022 base knocks this year, and their team batting average is at .258. The Pirates have hit 179 doubles as a team and have smacked 139 baseballs out of the park. They have 582 runs scored while holding a team OBP of .335. As a unit, the Pittsburgh Pirates are scoring 5.1 runs per game, which puts them at 4th in baseball.

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The Pirates have an earned run average of 4.29 over the course of the season (20th in baseball), and they have rung up 1,059 hitters. Pirates pitchers have conceded 117 home runs and 551 runs (24th in the league). Their pitching staff has walked 416 opposing players and their FIP is 3.92 as a unit over the course of the season. Pittsburgh has surrendered 936 base knocks (8.3 per 9 innings) as well as 487 earned runs. They have accumulated a K/BB ratio of 2.55 and their pitching staff sits with a WHIP of 1.33.

The Pirates have sent 363 relief pitchers to the mound over the course of the season. The relievers have inherited 142 base runners for the year with 32.4% of those players crossing home plate. The bullpen are sitting with 50 holds on the campaign (24th in baseball). Pirates relief pitchers have entered the game with runners on 102 times as well as having 108 appearances in high leverage situations. They have compiled 23 saves for the season and have blown 20 of their 43 save opportunities. The Pirates bullpen have a save rate of 53.5% and have entered the game in 94 save situations.

The Pirates have converted 68.6% of balls in play into outs out of 9,186 innings, which ranks them 27th in professional baseball. The Pittsburgh Pirates have 3,062 putouts on the campaign, as well as 891 assists and 69 errors. Their fielding rate is holding at .983 which is 23rd in pro baseball, and have earned 90 double plays.

Skenes (30-22 mark in his career) has a FIP of 2.47 while he has faced 1,759 hitters in the major leagues. He has allowed 337 hits (6.8 hits per 9 innings) with 106 free passes. His ERA is 2.51 (124 earned runs allowed) and he has a WHIP of 0.997. Skenes has pitched in 444 innings and has totaled 542 K's in his MLB career.

The Milwaukee Brewers have a team on-base percentage of .337 as well as a team batting average of .253 for the season. They have been rung up on 916 occasions (22nd in baseball) and have tallied 959 base hits. Milwaukee has a total of 101 home runs over the course of the season to go along with 528 RBIs. The Brewers have a team SLG% of .397 and they are scoring 4.98 runs per outing (5th in the league). They have 203 two-baggers, while getting a free base 465 times and notching 558 runs.

The Milwaukee pitching staff have yielded 424 runs this year while holding an ERA of 3.48 (387 earned runs relinquished). They have allowed 110 HR's and they allow 3.82 runs per 9 innings (2nd in the league). The Brewers have a team WHIP of 1.164 with a FIP of 3.52 as a unit for the year. They have earned a strikeout to walk ratio of 9.80 (1,094 strikeouts against 351 bases on balls). They are sitting at 2nd in MLB as a pitching staff in total hits relinquished with 813.

Milwaukee relievers hold an inherited score percentage of 42.9% of 126 inherited runners. Their relief pitchers have come in 108 times in high leverage situations and also on 88 occasions with runners on base. Sitting with 102 save situations, the Brewers have recorded 52 holds and 15 blown saves. They rank 11th in MLB with a save percentage of 69.4%, and they have sent 341 bullpen pitchers to the mound on the year.

The Milwaukee Brewers have gotten 78 double plays and have accounted for a fielding rate of .987 (8th in pro baseball). The Brewers have racked up 867 assists, 49 errors and are sitting with 3,002 putouts on the season. In their 9,006 innings played, the Brewers have accumulated a defensive efficiency of 71.0% (8th in professional baseball).

During his career, Harrison has allowed 259 base knocks while he has totaled 292 K's in 277 frames. Harrison (17-11 career mark) has earned a 3.99 ERA and has conceded 8.4 hits per nine innings. He has given up a total of 123 ER's while holding a WHIP of 1.247 and having a FIP of 3.9. He has a strikeout to walk ratio of 3.36 and he has faced 1,176 batters during his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Pittsburgh (+125)

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