Pittsburgh Pirates vs New York Yankees Prediction, 7/21/2026 MLB Picks, Best Bets & Odds
Game: Pittsburgh Pirates vs New York Yankees
Date: Tuesday, July 21, 2026
Location: Yankee Stadium in Bronx, NY
TV: YES
Odds/Point Spread: Pittsburgh (+126) New York (-152)
The Pittsburgh Pirates (52-48) are traveling to Yankee Stadium on Tuesday where they will attempt to beat the New York Yankees (55-44). The moneyline on this contest has the Pirates at +126 while the Yankees are at -152. The over/under has been set at 9. The pitchers taking the mound will be Bubba Chandler and Will Warren.

Pittsburgh has a slugging percentage of .428 and have been rung up 946 times, while taking a walk on 373 occasions. They have accounted for 509 runs batted in as well as 914 base knocks for the year, while their batting average is .263. The Pirates have hit 162 doubles as a team and have hit 129 baseballs out of the park. They have earned a total of 533 runs and have an on-base percentage of .341. As a unit, the Pittsburgh Pirates are putting up 5.3 runs per outing, which is 2nd in the league.
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Their strikeout to walk ratio sits at 2.53 and the pitching staff has earned a collective WHIP of 1.31. Pirates pitchers have allowed 104 home runs in addition to 479 runs in total (23rd in baseball). Pittsburgh has yielded 811 hits (8.2 per 9 innings) as well as 423 earned runs. The Pirates hold a team ERA of 4.26 so far this year (19th in baseball), and their staff has rung up 917 hitters. Their pitching staff has walked 362 players from the other team and their FIP is 3.96 as a unit this season.
The Pirates relief pitchers have a save percentage of 51.4% and stepped onto the hill in 85 save situations. They have 19 saves over the course of the season and have blown 18 out of their 37 chances to save the game. The relief pitchers have inherited 129 base runners on the campaign and 31.0% of those runners ended up crossing the plate. Pirates bullpen pitchers have stepped onto the hill with runners on 90 times as well as having 92 appearances in high leverage situations. The Pirates have sent 319 relievers to the mound so far this year. The relief pitchers have accumulated 47 holds so far this year (21st in MLB).
The Pirates have turned 69.0% of balls hit into play into outs out of their 8,037 innings, which ranks them 24th in the majors. The Pittsburgh Pirates have accumulated 2,679 putouts thus far, as well as 790 assists and 58 errors. Their fielding percentage sits at .984 which has them ranked 21st in the majors, and they have turned 78 double plays.
Chandler (7-9 career mark) holds a FIP of 4.53 while going up against 545 batters during his time in the major leagues. He has surrendered 107 base knocks (7.7 hits per 9 innings) and has had 59 walks. His ERA is 4.60 (64 ER's allowed) and his career WHIP is 1.326. Chandler has taken the ball for 125 innings and has racked up 116 strikeouts in his pro baseball career.
The New York Yankees have an on-base percentage of .316 and a batting average of .236 this season. They have struck out on 891 instances (5th in baseball) and have accounted for 773 base hits. New York has a total of 144 home runs this year as well as 445 RBIs. The Yankees hold a slugging percentage of .422 and they tally 4.72 runs per contest (10th in the league). They have 149 two-baggers, while taking a walk 374 times as well as putting up 467 runs.
The New York pitching staff have given up 382 runs for the year while holding a team ERA of 3.40 (332 earned runs conceded). They have allowed 99 homers and they relinquish 3.91 runs per 9 innings (4th in the league). The Yankees are sitting with a team WHIP of 1.191 and have a FIP of 3.76 as a team so far this year. Their strikeout to walk ratio is 8.80 (863 strikeouts against 299 free passes). They come in at 4th in MLB as a staff in total hits allowed with 747.
They are ranked 20th in baseball holding a save percentage of 59.0%, and they have sent 328 relief pitchers onto the diamond on the year. Their relief pitchers have come in 107 times in high leverage situations in addition to 112 occasions with runners on. With 87 save situations, the Yankees have recorded 47 holds and also 16 blown saves. New York has had bullpen pitchers step onto the hill in 39 save chances and they have converted 23 saves. New York relief pitchers hold an inherited score rate of 25.7% of 167 inherited runners.
In 7,908 innings on the diamond, the Yankees are sitting with a defensive efficiency of 71.0% (7th in the majors). The New York Yankees have turned 70 double plays and own a fielding percentage of .984 (20th in professional baseball). The Yankees have 862 assists, 56 errors and have 2,636 putouts for the year.
In his MLB career, Warren has allowed 292 hits and he has 296 K's in 283 innings pitched. He has conceded a total of 150 ER's while earning a WHIP of 1.413 and a FIP of 4.7. His strikeout to walk ratio is 2.74 and he has gone up against 1,250 hitters so far in his MLB career. Warren (16-15 record in his career) has earned a 4.77 earned run average while giving up 9.3 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Pittsburgh (+126)
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Additional Resources:
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