Pittsburgh Pirates vs Toronto Blue Jays Prediction, 5/22/2026 MLB Picks, Best Bets & Odds

Game: Pittsburgh Pirates vs Toronto Blue Jays

Date: Friday, May 22, 2026

Location: Rogers Centre in Toronto, ON

TV: Sportsnet

Odds/Point Spread: Pittsburgh (+110) Toronto (-132)

The Toronto Blue Jays (22-27) host the Pittsburgh Pirates (25-24) at Rogers Centre on Friday. The moneyline on this game has Pittsburgh at +110 while Toronto is at -132. The over/under has been set at 8.5. The pitchers who are expected to start will be Bubba Chandler and Kevin Gausman.

Pittsburgh has a slugging % of .389 and have struck out 450 times, while being walked on 194 occasions. They have accrued 231 RBI's in addition to 431 base knocks for the season, and their batting average comes in at .252. The Pirates have hit 71 doubles as a squad and have hit 50 balls out of the park. They have tallied 242 runs scored and hold an OBP of .335. As a unit, the Pittsburgh Pirates are putting up 4.9 runs per game, which has them sitting at 6th in the league.

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They have a strikeout to walk ratio of 2.49 and their pitching staff has recorded a WHIP of 1.23. Pirates pitchers have given up 43 home runs and 220 runs (16th in the league). Pittsburgh has allowed 374 base knocks (7.5 per 9 innings) and 193 earned runs. The Pirates have compiled a team earned run average of 3.89 over the course of the season (10th in MLB), and they have struck out 434 batters. Their pitching staff has walked 174 players from the other team and their FIP is 3.79 as a squad on the campaign.

The Pirates relief pitchers have earned a save percentage of 40.0% and have entered the game in 50 save situations. They have recorded 8 saves on the campaign and have not converted 12 of their 20 chances to save the game. The relief pitchers have inherited 59 base runners over the course of the season and 35.6% of those players crossing the plate. Pirates bullpen pitchers have entered the contest with runners on base 49 times in addition to having 54 appearances in high leverage situations. The Pirates have sent 168 relief pitchers to the mound on the year. The relief pitchers have a total of 29 holds so far this year (11th in MLB).

The Pirates have turned 71.1% of balls hit into play into outs out of 4,020 innings, which has them sitting 8th in pro baseball. The Pittsburgh Pirates are sitting with 1,340 putouts on the year, in addition to 414 assists and 25 errors. Their fielding rate is holding steady at .986 which has them ranked 20th in pro baseball, and they have turned 36 double plays.

Chandler has thrown 73 frames and has 67 punch outs so far in his career. Chandler (5-6 mark in his career) holds a FIP of 4.61 while he has gone up against 313 opposing hitters in the major leagues. His ERA is 4.68 (38 ER's allowed) and his career WHIP is 1.272. He has surrendered 58 base knocks (7.1 hits per 9 innings) and has 35 free passes.

The Blue Jays have a SLG% of .369 and they score 4.08 runs per game (24th in baseball). They have hit 72 doubles, while taking a walk 141 times and earning 200 runs. Toronto has accounted for 44 home runs this season to go along with 193 RBIs. They have been rung up on 342 occasions (30th in MLB) and have accounted for 401 hits. The Toronto Blue Jays have a team OBP of .306 and a batting average of .243 so far this season.

The Blue Jays have a team WHIP of 1.290 in addition to having a FIP of 3.69 as a staff on the campaign. Their strikeout to walk ratio is 9.20 (444 strikeouts against 153 walks). They rank 21st in the league as a staff in total hits conceded with 407. They have relinquished 49 HR's and they surrender 4.40 runs per 9 innings (11th in the league). The Toronto pitching staff have yielded 212 runs on the season while having a team ERA of 4.00 (193 earned runs relinquished).

Toronto bullpen pitchers hold an inherited score rate of 22.8% out of 79 inherited runners. Their relief pitchers have taken the field 60 times in high leverage situations and on 58 occasions with runners on base. With 52 save situations, the Blue Jays have tallied 30 holds and also 10 blown saves. They sit at 27th in baseball holding a save percentage of 50.0%, and they have dispatched 184 relievers to the hill so far this season.

In 3,909 innings on the field, the Blue Jays have a defensive efficiency of 68.0% (27th in baseball). The Toronto Blue Jays have gotten 36 double plays and have a fielding rate of .982 (27th in MLB). The Blue Jays have accrued 406 assists, 31 errors and have accumulated 1,303 putouts for the year.

Thus far in his career, Gausman has conceded 1,886 hits while tallying 2,007 K's in 1,968 innings pitched. He has conceded 832 ER's while earning a WHIP of 1.235 and a FIP of 3.7. His K/BB ratio is 3.69 and he has gone up against 8,217 hitters thus far in his career. Gausman (115-116 career record) has earned a 3.80 ERA and has given up 8.6 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Pittsburgh (+110)

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