Sacramento Athletics vs San Diego Padres Prediction, 5/22/2026 MLB Picks, Best Bets & Odds

Game: Sacramento Athletics vs San Diego Padres

Date: Friday, May 22, 2026

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Sacramento (+125) San Diego (-150)

The San Diego Padres (29-20) will go up against the Sacramento Athletics (25-24) at Petco Park on Friday. The odds on this game have the Athletics at +125 while the Padres are at -150. The betting total comes in at 9. The pitchers taking the mound are Jeffrey Springs and Walker Buehler.

The Athletics have tallied 77 doubles as a team and have hit 54 baseballs out of the park. Sacramento owns a slugging percentage of .401 and have been called out on strikes 422 times, while drawing a walk on 183 occasions. As a team, the Sacramento Athletics are recording 4.5 runs/g, which has them at 12th in MLB. They have accumulated 217 RBI's and 418 hits on the season, and their batting average is sitting at .251. They have racked up 221 runs scored and have an OBP of .329.

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The Athletics hold a team ERA of 4.32 for the season (23rd in the league), and the staff has struck out 384 batters. Athletics pitchers have surrendered 63 home runs and 226 runs in total (20th in the league). Their pitching staff has walked 198 players from the other team and their FIP is 4.75 as a squad on the campaign. Sacramento has surrendered 427 base knocks (8.8 per 9 innings) as well as 210 earned runs. They have a K/BB ratio of 1.94 and the pitching staff has a collective WHIP of 1.43.

The Athletics bullpen have recorded a save percentage of 56.0% and have come into the game in 64 save situations. They have recorded 14 saves on the year and have blown 11 out of their 25 chances to get a save. The relief pitchers have inherited 84 base runners for the season and 29.8% of those players crossing the plate. Athletics bullpen pitchers have entered the contest with runners on base 56 times in addition to having 61 appearances in high leverage situations. The Athletics have dispatched 168 relief pitchers to the mound on the year. The relief pitchers have notched 37 holds on the year (5th in MLB).

The Athletics have converted 70.2% of balls hit into play into outs out of 3,939 innings, which has them ranked 16th in the majors. The Sacramento Athletics have earned 1,313 putouts so far this season, in addition to 387 assists and 18 errors. Their fielding percentage is holding at .990 which puts them in 5th in pro baseball, and have 31 double plays.

Springs has taken the mound for 539 frames and has earned 544 strikeouts during his pro baseball career. His ERA is 3.67 (220 ER's allowed) and his WHIP is 1.231. He has surrendered 490 base knocks (8.2 hits per 9 innings) and has 174 walks. Springs (37-27 win-loss mark in his career) is the owner of a FIP of 3.62 while he has gone up against 2,263 hitters in the major leagues.

The San Diego Padres have an on-base percentage of .292 and a team batting average of .221 on the year. They have struck out on 414 occasions (15th in baseball) and have earned a total of 354 hits. San Diego has tallied 49 home runs on the year and 193 RBIs. The Padres hold a slugging percentage of .366 and they have an average of 4.08 runs per game (23rd in the league). They have recorded 72 two-baggers, while walking 155 times as well as scoring 200 runs.

The San Diego pitching staff have yielded 197 runs this season and come in with a team ERA of 3.93 (191 earned runs surrendered). They have surrendered 41 home runs and they surrender 4.06 runs per 9 innings (9th in the league). The Padres have a team WHIP of 1.247 and are the owners of a FIP of 3.66 as a staff over the course of the season. They currently have a K/BB ratio of 8.80 (426 strikeouts against 166 walks). They rank 9th in the league as a staff in total hits relinquished with 379.

They sit at 8th in the league with a save rate of 69.2%, and they have dispatched 163 relief pitchers to the hill on the year. Their relief pitchers have stepped onto the mound 54 times in high leverage situations and also on 44 occasions with base runners. Sitting with 61 save situations, the Padres have 33 holds in addition to 8 blown saves. San Diego has had bullpen pitchers step onto the mound in 26 save opportunities and they have walked away with 18 saves. San Diego relievers have an inherited score rate of 35.1% out of 77 inherited runners.

Out of their 3,933 innings played, the Padres hold a defensive efficiency of 70.4% (13th in professional baseball). The San Diego Padres have turned 37 double plays and have notched a fielding percentage of .991 (1st in pro baseball). The Padres have accrued 431 assists, 16 errors and have a total of 1,311 putouts so far this season.

Buehler (60-31 win-loss mark in his career) has a 3.59 ERA while surrendering 7.8 hits per 9 innings. His strikeout to walk ratio is 3.33 and he has faced 3,647 opposing batters during his pro baseball career. He has given up a total of 351 earned runs while holding a WHIP of 1.164 and having a FIP of 3.5. During his pro baseball career, Buehler has conceded 760 base knocks while he has accumulated 883 punch outs in 880 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take San Diego (-150)

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